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The map label for this gene is neuA [H]

Identifier: 37680825

GI number: 37680825

Start: 2671865

End: 2672740

Strand: Direct

Name: neuA [H]

Synonym: VV2641

Alternate gene names: 37680825

Gene position: 2671865-2672740 (Clockwise)

Preceding gene: 37680824

Following gene: 37680826

Centisome position: 79.65

GC content: 50.57

Gene sequence:

>876_bases
ATGAACCACGAGCAACTTCTTAAGGAGCTGGAAGAAAACGCCTGTCTTGATCTGCATAAACTCTATTACGCCAACCCAGA
TAAGCGCTTTTACGCTCTGCTGGCGGAGCTTTACCAGTTACGCAAACAACATGGGCTGACAACACGCTTATCTCCTTACG
TCACGGAAATTGAATCTCTGACCAAAGCGCTCACTCTGACCAAAGAACGAAGTCTCACCGATGAGCAAAAGGGTCACACC
GTGACACCAGAGCAATTAGACCACTTAGTTGAAACGCTCGACTTTAACCAAAGGGCCCACCGCATGAGTCGTTTTATTTT
AACCAAAGATAACCACAAAGCGTTTAGTAAACCGGTTGAGCTGGTGATGTACGGCGATTCCATTACCGAGTGGGGCCCTT
GGCACGATGCTTTTTCTGGTTTTCAAGTCGCGAATCGCGGGCTCGCAGGGGACACCACCGCAGGCATGCTTGAACGCATT
GACACCACGTTGGTGTGTCAGCCGAAACTGGTGTGTATCATGGCGGGGATTAACGATTTAGCGCAGGGCTACTCGGTGCA
GCAAGTCGTGGAAAATTACTGTCGAATGCTGGCCATTTGGCAAGAACAGGGCATTGAAGTGTGGGTGCAGTCCACGCTGT
ATGTGGGCGAGCGAATGTCATCATTGAACCCACTGGTCAGCGAGTTAAATCGTCAATTAGGGCAAATATGTCAGGCGCAA
TCACTGCGTTTTATCGATCTCAACGCCACGCTCTGCCCAGAGCAGACACTGCCTCTTGATTGCAGTTGCGATGACTTACA
CCTCAACTCGCACGCTTACGCGCAATGGCTTTCTGTGCTCACGCCAATGCTGGACGCTCGTTTCGCTACGGCATAA

Upstream 100 bases:

>100_bases
TATTGGTGGAAAAAGCGCGTGATGGCCGAGCACTGCCGCTTAAAGTGTATGTGCCAAGCAAGCTCAAGCTAAGAGGAACG
ACTCAGGAGAGGAGCCAAGC

Downstream 100 bases:

>100_bases
AGCAGTGACACCATTTTTATCCAAAGCACGCTGAGCGTGCTTTCTTTTTATCTCTATTTTTCAATAGTTAAAGTTCAAAC
CCTTTCTCATTCACTGCTGT

Product: lysophospholipase L1

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNHEQLLKELEENACLDLHKLYYANPDKRFYALLAELYQLRKQHGLTTRLSPYVTEIESLTKALTLTKERSLTDEQKGHT
VTPEQLDHLVETLDFNQRAHRMSRFILTKDNHKAFSKPVELVMYGDSITEWGPWHDAFSGFQVANRGLAGDTTAGMLERI
DTTLVCQPKLVCIMAGINDLAQGYSVQQVVENYCRMLAIWQEQGIEVWVQSTLYVGERMSSLNPLVSELNRQLGQICQAQ
SLRFIDLNATLCPEQTLPLDCSCDDLHLNSHAYAQWLSVLTPMLDARFATA

Sequences:

>Translated_291_residues
MNHEQLLKELEENACLDLHKLYYANPDKRFYALLAELYQLRKQHGLTTRLSPYVTEIESLTKALTLTKERSLTDEQKGHT
VTPEQLDHLVETLDFNQRAHRMSRFILTKDNHKAFSKPVELVMYGDSITEWGPWHDAFSGFQVANRGLAGDTTAGMLERI
DTTLVCQPKLVCIMAGINDLAQGYSVQQVVENYCRMLAIWQEQGIEVWVQSTLYVGERMSSLNPLVSELNRQLGQICQAQ
SLRFIDLNATLCPEQTLPLDCSCDDLHLNSHAYAQWLSVLTPMLDARFATA
>Mature_291_residues
MNHEQLLKELEENACLDLHKLYYANPDKRFYALLAELYQLRKQHGLTTRLSPYVTEIESLTKALTLTKERSLTDEQKGHT
VTPEQLDHLVETLDFNQRAHRMSRFILTKDNHKAFSKPVELVMYGDSITEWGPWHDAFSGFQVANRGLAGDTTAGMLERI
DTTLVCQPKLVCIMAGINDLAQGYSVQQVVENYCRMLAIWQEQGIEVWVQSTLYVGERMSSLNPLVSELNRQLGQICQAQ
SLRFIDLNATLCPEQTLPLDCSCDDLHLNSHAYAQWLSVLTPMLDARFATA

Specific function: Unknown

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087 [H]

Pfam domain/function: PF02348 CTP_transf_3; PF00657 Lipase_GDSL [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 33149; Mature: 33149

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHEQLLKELEENACLDLHKLYYANPDKRFYALLAELYQLRKQHGLTTRLSPYVTEIESL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TKALTLTKERSLTDEQKGHTVTPEQLDHLVETLDFNQRAHRMSRFILTKDNHKAFSKPVE
HHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCCEE
LVMYGDSITEWGPWHDAFSGFQVANRGLAGDTTAGMLERIDTTLVCQPKLVCIMAGINDL
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHCHHHH
AQGYSVQQVVENYCRMLAIWQEQGIEVWVQSTLYVGERMSSLNPLVSELNRQLGQICQAQ
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLRFIDLNATLCPEQTLPLDCSCDDLHLNSHAYAQWLSVLTPMLDARFATA
CCEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHEQLLKELEENACLDLHKLYYANPDKRFYALLAELYQLRKQHGLTTRLSPYVTEIESL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
TKALTLTKERSLTDEQKGHTVTPEQLDHLVETLDFNQRAHRMSRFILTKDNHKAFSKPVE
HHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCCEE
LVMYGDSITEWGPWHDAFSGFQVANRGLAGDTTAGMLERIDTTLVCQPKLVCIMAGINDL
EEEECCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCHHHHHHHCHHHH
AQGYSVQQVVENYCRMLAIWQEQGIEVWVQSTLYVGERMSSLNPLVSELNRQLGQICQAQ
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLRFIDLNATLCPEQTLPLDCSCDDLHLNSHAYAQWLSVLTPMLDARFATA
CCEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464185 [H]