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The map label for this gene is argA

Identifier: 37680795

GI number: 37680795

Start: 2634195

End: 2635532

Strand: Direct

Name: argA

Synonym: VV2611

Alternate gene names: 37680795

Gene position: 2634195-2635532 (Clockwise)

Preceding gene: 37680794

Following gene: 37680796

Centisome position: 78.53

GC content: 47.83

Gene sequence:

>1338_bases
GTGAAAATTCGCAGCACTGCATTAGTTAAAGGTTTCAGACAATCCACTCCGTACGTAAACGCGCACCGCGGCAAAACTAT
GGTTATTCTCCTTGGTGGTGAAGCGATCGCTGACAAAAACTTCAGCAATATTATTAATGATATAGCTCTAATGCACAGCC
TTGGCGTTAAAGTGGTTCTGGTCTATGGTGCCAGACCGCAAATCAATCAATTACTTGACAAGCAATCAAGCCAAACCCCT
TATCACAAACACATTCGTGTGACTGACGAAAACTCACTTTCGATAGTTATGCAAGCCGCCGGACAGTTGCAATTGGCGAT
CACAGCCAGCCTCTCCATGAGCTTGAATAATACGCCGATGGCCGGAACGCACCTCAACGTGGTCAGTGGAAATTTTGTCA
TCGCTCAACCATTAGGTATAGATGAAGGTGTCGATTACTGCCACAGTGGTCGCATTCGTCGCATTGATACCGAGGCCATC
AATCGCTCCTTGGATCAAGGTTCCATCGTACTGCTGGGGCCGATTGCCAGCTCGGTGACTGGTGAATGCTTTAACTTGCT
TTCTGAAGAAGTAGCAACACAAGTGGCGATCAAACTTAAAGCCGACAAACTGATTGGCTTTTGTTCTGAGCAAGGCGTGA
TTGATGAAGAGGGCAATGCCGTCGCCGAGTTGTTTCCAAGCGATGCGGAGAAATTCATTCAAAAGCTCTCGGTCGATGTC
GATCCCGATAGTGACTTCCATTCCGGCACATTGCGTTTTCTCAAAGGGGCAGTGGCAGCTTGCCGCGCTGGCGTTCCCCG
TAGCCATTTAATCAGTTACAAAATTGATGGGGCTTTAATCCAAGAACTGTTTTCATTTGACGGTATCGGCACGCAAGTGG
TCATGGCCAGTGCTGAACAAGTTCGTCAGGCTTGCATTGATGATATTGGCGGCATTCTTGAACTGATTCGCCCTCTGGAA
GAGCAAGGCATTCTAGTAAGGCGCTCTCGCGAGCAACTTGAGCAAGAGGTTGAACGCTTTACCATCATTGAGAAAGATGG
CCTGATCATTGGCTGCGCCGCCTTGTACCCTTATATCGATGAGCATATGGCGGAGATGGCGTGTGTGGCCATTCATCCTG
ATTATCGCGATGGTAACCGTGGCCTGTTGCTGCTCAATTACATGAAGCATCGCTCGAAATCCATCGGCATTGAGCAAATT
TTTGTTCTCACCACGCACAGCGTTCATTGGTTTAGAGAGCAAGGTTTCTACGAAATTGGCGTCGACTCACTGCCAATGGC
GAAGAAAAGTTTGTACAACTATCAGCGTCGTTCAAAAATTTTGGCACTGCCACTTTGA

Upstream 100 bases:

>100_bases
TCACTCAGATCAAACGTGGTTAAATTAATAAAAAACCGCTTGCCAACAAGGGAATAAAAAGACAATATTTCAGCATAAAT
AGTCACAAGGAAGTCATATT

Downstream 100 bases:

>100_bases
CCTAAGATTAGTATTTCCTGCTGATGAACAGGGTTAACACCATATTCAATGCTTTACATCTTGTCTGTTCAAAGTTTGTG
CTTTTTTTCGTTCGGTGACT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVLVYGARPQINQLLDKQSSQTP
YHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPMAGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAI
NRSLDQGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDV
DPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQVRQACIDDIGGILELIRPLE
EQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYIDEHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQI
FVLTTHSVHWFREQGFYEIGVDSLPMAKKSLYNYQRRSKILALPL

Sequences:

>Translated_445_residues
MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVLVYGARPQINQLLDKQSSQTP
YHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPMAGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAI
NRSLDQGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDV
DPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQVRQACIDDIGGILELIRPLE
EQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYIDEHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQI
FVLTTHSVHWFREQGFYEIGVDSLPMAKKSLYNYQRRSKILALPL
>Mature_445_residues
MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVLVYGARPQINQLLDKQSSQTP
YHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPMAGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAI
NRSLDQGSIVLLGPIASSVTGECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDV
DPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQVRQACIDDIGGILELIRPLE
EQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYIDEHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQI
FVLTTHSVHWFREQGFYEIGVDSLPMAKKSLYNYQRRSKILALPL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain

Homologues:

Organism=Escherichia coli, GI1789181, Length=445, Percent_Identity=63.5955056179775, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGA_VIBVU (P59294)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_760680.1
- ProteinModelPortal:   P59294
- SMR:   P59294
- GeneID:   1178706
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_1799
- HOGENOM:   HBG545264
- OMA:   APYIHAF
- ProtClustDB:   PRK05279
- BioCyc:   VVUL216895:VV1_1799-MONOMER
- BRENDA:   2.3.1.1
- GO:   GO:0005737
- HAMAP:   MF_01105
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167
- Gene3D:   G3DSA:3.40.1160.10
- Gene3D:   G3DSA:3.40.630.30
- PIRSF:   PIRSF000423
- TIGRFAMs:   TIGR01890

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1; SSF53633 Aa_kinase; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.1

Molecular weight: Translated: 49034; Mature: 49034

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS51186 GNAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVL
CCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCCEEEE
VYGARPQINQLLDKQSSQTPYHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPM
EECCCCHHHHHHHCCCCCCCCHHEEEEECCCCEEEEEECCCCEEEEEEEEEEEEECCCCC
AGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAINRSLDQGSIVLLGPIASSVT
CCCEEEEEECCEEEEECCCCCCCCHHHHCCCEEEECHHHHHCCCCCCCEEEEECCHHHHH
GECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDV
HHHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCCCCCCEEEHHCCCHHHHHHHHHCCCC
DPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQ
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECHHHHHHHHHCCCCCHHHHHHHHHH
VRQACIDDIGGILELIRPLEEQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYID
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHH
EHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQIFVLTTHSVHWFREQGFYEIG
HHHHHEEEEEECCCCCCCCCCEEEEHHHHHHCCCCCCEEEEEEEECCCHHHHHCCCEEEC
VDSLPMAKKSLYNYQRRSKILALPL
CCCCCHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MKIRSTALVKGFRQSTPYVNAHRGKTMVILLGGEAIADKNFSNIINDIALMHSLGVKVVL
CCCCHHHHHHHHHHCCCCEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCCEEEE
VYGARPQINQLLDKQSSQTPYHKHIRVTDENSLSIVMQAAGQLQLAITASLSMSLNNTPM
EECCCCHHHHHHHCCCCCCCCHHEEEEECCCCEEEEEECCCCEEEEEEEEEEEEECCCCC
AGTHLNVVSGNFVIAQPLGIDEGVDYCHSGRIRRIDTEAINRSLDQGSIVLLGPIASSVT
CCCEEEEEECCEEEEECCCCCCCCHHHHCCCEEEECHHHHHCCCCCCCEEEEECCHHHHH
GECFNLLSEEVATQVAIKLKADKLIGFCSEQGVIDEEGNAVAELFPSDAEKFIQKLSVDV
HHHHHHHHHHHHHHHHEEEEHHHHHEECCCCCCCCCCCCEEEHHCCCHHHHHHHHHCCCC
DPDSDFHSGTLRFLKGAVAACRAGVPRSHLISYKIDGALIQELFSFDGIGTQVVMASAEQ
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEEEEECHHHHHHHHHCCCCCHHHHHHHHHH
VRQACIDDIGGILELIRPLEEQGILVRRSREQLEQEVERFTIIEKDGLIIGCAALYPYID
HHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHH
EHMAEMACVAIHPDYRDGNRGLLLLNYMKHRSKSIGIEQIFVLTTHSVHWFREQGFYEIG
HHHHHEEEEEECCCCCCCCCCEEEEHHHHHHCCCCCCEEEEEEEECCCHHHHHCCCEEEC
VDSLPMAKKSLYNYQRRSKILALPL
CCCCCHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA