Definition Vibrio vulnificus YJ016 chromosome I, complete sequence.
Accession NC_005139
Length 3,354,505

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The map label for this gene is hsdR [H]

Identifier: 37680384

GI number: 37680384

Start: 2204823

End: 2207615

Strand: Direct

Name: hsdR [H]

Synonym: VV2200

Alternate gene names: 37680384

Gene position: 2204823-2207615 (Clockwise)

Preceding gene: 37680383

Following gene: 37680399

Centisome position: 65.73

GC content: 46.37

Gene sequence:

>2793_bases
GTGTCCTTTATTCAACCCTCTGGCCTAGATTTGCTTCTGCCAAGCATTCACGAGGCGATTGAACGTAAAAAGTCACACCA
GCGCCCCTTAAAGTTGCGCATCCTAACGTCAGATTACCTGCACATCACTCATCCTATTGCGTTGCGCTCTCTGATTGAAC
TAGAAGGAGATGAGATAGAAATTAAGATTTTTGAAGCCAATAACCGCAGTTTTCACCTCAAATCGTACATCTTTGTTCGC
AGCGATGAAGCTCGTTCCATTTACCAAGGAGCTGCTTTTGTTGGCTCTAACAACATCAGTAAAACCGCACTCACCGATGC
CCATGAATGGTGCCTACGTTTAGATTACCAGCAACCAGACAACTCCCCTCAAGCGGCGCAGTTTCACAATATCCGAACAC
AGTTTGACAAACTGTTTCATCATCCATCTGCCATATTGCTGACGGATGAATGGATTGACAGCTACATCAGAAGAAGAACA
CCACCCAAGCTTTCAGCAGTCGGTGATACGACGCTATTGGATAACGAAGAATATTCACCCAACTCGGCACAGTTAGACGC
ATTGCAACGACTCAGCGAGACTCGTCAAAAAGGCAATGTTCGTGGATTGGTTGTGATGGGCACTGGCATGGGAAAAACAT
GGTTATCTGCGTTTGATGCGAAACAACTGGAAGCAAAGCGAGTTCTGTTCGTTGCTCACCGCGAAGAAATTCTGACCCAA
GCACTGATGACTTTCGCTAAACTTTGGCCCCAAAAATCCGCAGGCTACTATCACGGTAAGAGCAAACAAAAAAACAAAGA
GATGCTGTTTGCCTCAGTGCAGAGTTTAGGTAAAACAGCACAACTCAAACACTTTTCGCCCGACTACTTTGATTACATCG
TGGTTGATGAATTTCATCATGCGAGCGCCAAAACGTATCTTAATATCCTCAATCACTTTGAACCTAAATTTTTACTCGGG
CTAACTGCTACTCCAGAACGGACAGACCAAGCGAACATCCTCTCGCTTTGCCACGACAACTTAGTGTTTGAACGTAACTT
AGTGCATGGTATCAATGATGAAATTCTGGTGCCTTTTCACTACCACGGCATCTGGGATGACTCGGTCGATTATCAAGAGA
TCCCATGGCGAAATGGTAAATTTGACCCCACCGCCCTTGACGCCCAGTTTGCAACCACACGACGTGCCAAACATATTTTT
AAACATTGGCAAAACAGGCAACAAACTCGCACCTTGGCGTTTTGTGTATCCAAAAAGCACGCTGATTTTATGGCGCAGCA
CTTCAATCAAACTTTTGCAGATAAAGGCTTGAGGGCGCTTTCTGTACACAGTGATTCCTCCATTCGTCGTAATGAAGCGT
TAAGCATGCTGGATAAAGGAGAAATTCAAATTCTCTTCTCGGTTGATCTGTTCAACGAAGGGACTGATTTACCCTCAATC
GATACCGTGCTAATGCTGCGCCCGACTGAATCCAACATCGTTTTCATTCAACAATTGGGCCGAGGACTTCGTCGTCACAC
GGACAAATCACACTTGGTGGTATTGGATTTCATTGGGAACCATCGCTCGTTTTTGAACAAGAAAGAAATTTTAGGGATCA
GCACATCAAGCTCACTCGAACAGTTGAGTGATAAGTCACAAACACGGCCCGAATTAGGCAAAGGTTGCTTTACCAACATC
GATCCGAAAATCATCGATTTTTGGCAAACGCTGACAAAGCAGCTTCGCTATTCTGCTCAAGAAGAATTTGAACATTTGAC
CAACCATTTGGGCCATCGACCTCGTGCAGTCGAGTATTACCGAGCAGGTTACGACCTGGCCAAAGTGAACAAGCAGCACG
GTAGTTGGCTAGAGCTGGTCGCAAGTATGGACAAGGATCCGGAGTTAGATTACCTAGTTCGCGAACATCGTGACTTCTTT
GCCAATGCCATCCAAAAAGCAAGCATGACCAAGAGTTTTAAAGCGATATTGCTTGAAGCCTACCTCGAGCTGGATGGGTT
CAGAGATGCCCCGAGTATCGAAGTGCTCGCGAGTAAAAGTTGGCATGTGCTCTCTCGTTATCCCAAGCTAAAGGCATCCG
ACCTGTCAGAGATCAACCAACGCTTAACCGCAGACTCTCAGGCATGGTTGAAATATTGGCTTAGTAACCCTATCAACGCA
TTTGTAGGTGGAAACAAAACCAAGAACCGCGTTTGGTTTAAGCTTGTCGACGGAAAGCTCAAAGCTGACTTTGATGTCGC
CCCACTCCAGCAGCAAACATTCCATGACTTTGTCAAAGAGCTCGTGGACCTACAACTTGCTCAGTATTCAGACAGGCCAC
CTAAACAGACTCATCAAACAGTGGCACAACCGACCACTCCAGCAGAGGCAGCCAATGAAGGAACCTTGTTGCCCTACTAC
CCAAACCTTAAGATCGCTTGTGGTCATTTTAAGACCGGATCTCACGAGGAGGTTGAACACATCCCCGTTGATATGGCTAA
CCTCAATCCTCAAAAACATTTCTTGGCCAGAGCCTCTGGCAATTCGATGAACGGAGGCAAGACACCCATTTTAGATGGCG
ATTTGCTGTTACTCGAGTTTGTGACGCCGATATCCGCTGGCTCCATCACCGGCAACACCATGGCGATCGAAATCCAAGAT
AACTCGGGCGAGAATCAGTACCTACTACGTGTCGTGCAGAAGGATGCACAAGGGCGCTACTGGCTAAAAGCGAACAACCC
AGATTACGAGCTAATGCCTGCCAATGACTCGATGAAGACATTTGCGAGGCTGAAAAAGGTTATTACGCAGTAA

Upstream 100 bases:

>100_bases
CAAATCAGTCGCTTACTCTCAATTAACCACTGGTGGTGAAGACCCTCTGCTGCCGCAGCTGATCCACGCGATTAACCATG
CGACCGAGATAGAGATTGCA

Downstream 100 bases:

>100_bases
CATTATTCATTATCGTATGCATCAGAAAAACAGCGTTGGCATTACTTTGGATATTACTTGAAACAGTGGATTTGGTTGGA
CAAACTCGGCAAAATCACAA

Product: DNA or RNA helicase

Products: NA

Alternate protein names: R.EcoAI [H]

Number of amino acids: Translated: 930; Mature: 929

Protein sequence:

>930_residues
MSFIQPSGLDLLLPSIHEAIERKKSHQRPLKLRILTSDYLHITHPIALRSLIELEGDEIEIKIFEANNRSFHLKSYIFVR
SDEARSIYQGAAFVGSNNISKTALTDAHEWCLRLDYQQPDNSPQAAQFHNIRTQFDKLFHHPSAILLTDEWIDSYIRRRT
PPKLSAVGDTTLLDNEEYSPNSAQLDALQRLSETRQKGNVRGLVVMGTGMGKTWLSAFDAKQLEAKRVLFVAHREEILTQ
ALMTFAKLWPQKSAGYYHGKSKQKNKEMLFASVQSLGKTAQLKHFSPDYFDYIVVDEFHHASAKTYLNILNHFEPKFLLG
LTATPERTDQANILSLCHDNLVFERNLVHGINDEILVPFHYHGIWDDSVDYQEIPWRNGKFDPTALDAQFATTRRAKHIF
KHWQNRQQTRTLAFCVSKKHADFMAQHFNQTFADKGLRALSVHSDSSIRRNEALSMLDKGEIQILFSVDLFNEGTDLPSI
DTVLMLRPTESNIVFIQQLGRGLRRHTDKSHLVVLDFIGNHRSFLNKKEILGISTSSSLEQLSDKSQTRPELGKGCFTNI
DPKIIDFWQTLTKQLRYSAQEEFEHLTNHLGHRPRAVEYYRAGYDLAKVNKQHGSWLELVASMDKDPELDYLVREHRDFF
ANAIQKASMTKSFKAILLEAYLELDGFRDAPSIEVLASKSWHVLSRYPKLKASDLSEINQRLTADSQAWLKYWLSNPINA
FVGGNKTKNRVWFKLVDGKLKADFDVAPLQQQTFHDFVKELVDLQLAQYSDRPPKQTHQTVAQPTTPAEAANEGTLLPYY
PNLKIACGHFKTGSHEEVEHIPVDMANLNPQKHFLARASGNSMNGGKTPILDGDLLLLEFVTPISAGSITGNTMAIEIQD
NSGENQYLLRVVQKDAQGRYWLKANNPDYELMPANDSMKTFARLKKVITQ

Sequences:

>Translated_930_residues
MSFIQPSGLDLLLPSIHEAIERKKSHQRPLKLRILTSDYLHITHPIALRSLIELEGDEIEIKIFEANNRSFHLKSYIFVR
SDEARSIYQGAAFVGSNNISKTALTDAHEWCLRLDYQQPDNSPQAAQFHNIRTQFDKLFHHPSAILLTDEWIDSYIRRRT
PPKLSAVGDTTLLDNEEYSPNSAQLDALQRLSETRQKGNVRGLVVMGTGMGKTWLSAFDAKQLEAKRVLFVAHREEILTQ
ALMTFAKLWPQKSAGYYHGKSKQKNKEMLFASVQSLGKTAQLKHFSPDYFDYIVVDEFHHASAKTYLNILNHFEPKFLLG
LTATPERTDQANILSLCHDNLVFERNLVHGINDEILVPFHYHGIWDDSVDYQEIPWRNGKFDPTALDAQFATTRRAKHIF
KHWQNRQQTRTLAFCVSKKHADFMAQHFNQTFADKGLRALSVHSDSSIRRNEALSMLDKGEIQILFSVDLFNEGTDLPSI
DTVLMLRPTESNIVFIQQLGRGLRRHTDKSHLVVLDFIGNHRSFLNKKEILGISTSSSLEQLSDKSQTRPELGKGCFTNI
DPKIIDFWQTLTKQLRYSAQEEFEHLTNHLGHRPRAVEYYRAGYDLAKVNKQHGSWLELVASMDKDPELDYLVREHRDFF
ANAIQKASMTKSFKAILLEAYLELDGFRDAPSIEVLASKSWHVLSRYPKLKASDLSEINQRLTADSQAWLKYWLSNPINA
FVGGNKTKNRVWFKLVDGKLKADFDVAPLQQQTFHDFVKELVDLQLAQYSDRPPKQTHQTVAQPTTPAEAANEGTLLPYY
PNLKIACGHFKTGSHEEVEHIPVDMANLNPQKHFLARASGNSMNGGKTPILDGDLLLLEFVTPISAGSITGNTMAIEIQD
NSGENQYLLRVVQKDAQGRYWLKANNPDYELMPANDSMKTFARLKKVITQ
>Mature_929_residues
SFIQPSGLDLLLPSIHEAIERKKSHQRPLKLRILTSDYLHITHPIALRSLIELEGDEIEIKIFEANNRSFHLKSYIFVRS
DEARSIYQGAAFVGSNNISKTALTDAHEWCLRLDYQQPDNSPQAAQFHNIRTQFDKLFHHPSAILLTDEWIDSYIRRRTP
PKLSAVGDTTLLDNEEYSPNSAQLDALQRLSETRQKGNVRGLVVMGTGMGKTWLSAFDAKQLEAKRVLFVAHREEILTQA
LMTFAKLWPQKSAGYYHGKSKQKNKEMLFASVQSLGKTAQLKHFSPDYFDYIVVDEFHHASAKTYLNILNHFEPKFLLGL
TATPERTDQANILSLCHDNLVFERNLVHGINDEILVPFHYHGIWDDSVDYQEIPWRNGKFDPTALDAQFATTRRAKHIFK
HWQNRQQTRTLAFCVSKKHADFMAQHFNQTFADKGLRALSVHSDSSIRRNEALSMLDKGEIQILFSVDLFNEGTDLPSID
TVLMLRPTESNIVFIQQLGRGLRRHTDKSHLVVLDFIGNHRSFLNKKEILGISTSSSLEQLSDKSQTRPELGKGCFTNID
PKIIDFWQTLTKQLRYSAQEEFEHLTNHLGHRPRAVEYYRAGYDLAKVNKQHGSWLELVASMDKDPELDYLVREHRDFFA
NAIQKASMTKSFKAILLEAYLELDGFRDAPSIEVLASKSWHVLSRYPKLKASDLSEINQRLTADSQAWLKYWLSNPINAF
VGGNKTKNRVWFKLVDGKLKADFDVAPLQQQTFHDFVKELVDLQLAQYSDRPPKQTHQTVAQPTTPAEAANEGTLLPYYP
NLKIACGHFKTGSHEEVEHIPVDMANLNPQKHFLARASGNSMNGGKTPILDGDLLLLEFVTPISAGSITGNTMAIEIQDN
SGENQYLLRVVQKDAQGRYWLKANNPDYELMPANDSMKTFARLKKVITQ

Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788511, Length=342, Percent_Identity=26.3157894736842, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320539, Length=358, Percent_Identity=30.4469273743017, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR013670
- InterPro:   IPR007409 [H]

Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 106164; Mature: 106032

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIQPSGLDLLLPSIHEAIERKKSHQRPLKLRILTSDYLHITHPIALRSLIELEGDEIE
CCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCHHHHHHHHHCCCCEEE
IKIFEANNRSFHLKSYIFVRSDEARSIYQGAAFVGSNNISKTALTDAHEWCLRLDYQQPD
EEEEECCCCEEEEEEEEEEECCCHHHHHHCCCEECCCCCCHHHHHHHHHHHHEECCCCCC
NSPQAAQFHNIRTQFDKLFHHPSAILLTDEWIDSYIRRRTPPKLSAVGDTTLLDNEEYSP
CCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
NSAQLDALQRLSETRQKGNVRGLVVMGTGMGKTWLSAFDAKQLEAKRVLFVAHREEILTQ
CHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHH
ALMTFAKLWPQKSAGYYHGKSKQKNKEMLFASVQSLGKTAQLKHFSPDYFDYIVVDEFHH
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHH
ASAKTYLNILNHFEPKFLLGLTATPERTDQANILSLCHDNLVFERNLVHGINDEILVPFH
HHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEHHHHCCCCCCEEEEEE
YHGIWDDSVDYQEIPWRNGKFDPTALDAQFATTRRAKHIFKHWQNRQQTRTLAFCVSKKH
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ADFMAQHFNQTFADKGLRALSVHSDSSIRRNEALSMLDKGEIQILFSVDLFNEGTDLPSI
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCC
DTVLMLRPTESNIVFIQQLGRGLRRHTDKSHLVVLDFIGNHRSFLNKKEILGISTSSSLE
CEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCHHHEEEECCCHHHH
QLSDKSQTRPELGKGCFTNIDPKIIDFWQTLTKQLRYSAQEEFEHLTNHLGHRPRAVEYY
HHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RAGYDLAKVNKQHGSWLELVASMDKDPELDYLVREHRDFFANAIQKASMTKSFKAILLEA
HCCCCHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLELDGFRDAPSIEVLASKSWHVLSRYPKLKASDLSEINQRLTADSQAWLKYWLSNPINA
HHHHCCCCCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
FVGGNKTKNRVWFKLVDGKLKADFDVAPLQQQTFHDFVKELVDLQLAQYSDRPPKQTHQT
HCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VAQPTTPAEAANEGTLLPYYPNLKIACGHFKTGSHEEVEHIPVDMANLNPQKHFLARASG
HCCCCCCHHCCCCCCEEEECCCCEEEECCCCCCCCCCHHHCCCCHHCCCHHHHHEEECCC
NSMNGGKTPILDGDLLLLEFVTPISAGSITGNTMAIEIQDNSGENQYLLRVVQKDAQGRY
CCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCE
WLKANNPDYELMPANDSMKTFARLKKVITQ
EEEECCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFIQPSGLDLLLPSIHEAIERKKSHQRPLKLRILTSDYLHITHPIALRSLIELEGDEIE
CCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCHHHHHHHHHCCCCEEE
IKIFEANNRSFHLKSYIFVRSDEARSIYQGAAFVGSNNISKTALTDAHEWCLRLDYQQPD
EEEEECCCCEEEEEEEEEEECCCHHHHHHCCCEECCCCCCHHHHHHHHHHHHEECCCCCC
NSPQAAQFHNIRTQFDKLFHHPSAILLTDEWIDSYIRRRTPPKLSAVGDTTLLDNEEYSP
CCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCC
NSAQLDALQRLSETRQKGNVRGLVVMGTGMGKTWLSAFDAKQLEAKRVLFVAHREEILTQ
CHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEHHHHHHHHH
ALMTFAKLWPQKSAGYYHGKSKQKNKEMLFASVQSLGKTAQLKHFSPDYFDYIVVDEFHH
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHH
ASAKTYLNILNHFEPKFLLGLTATPERTDQANILSLCHDNLVFERNLVHGINDEILVPFH
HHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEHHHHCCCCCCEEEEEE
YHGIWDDSVDYQEIPWRNGKFDPTALDAQFATTRRAKHIFKHWQNRQQTRTLAFCVSKKH
ECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
ADFMAQHFNQTFADKGLRALSVHSDSSIRRNEALSMLDKGEIQILFSVDLFNEGTDLPSI
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCC
DTVLMLRPTESNIVFIQQLGRGLRRHTDKSHLVVLDFIGNHRSFLNKKEILGISTSSSLE
CEEEEEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHCCHHHEEEECCCHHHH
QLSDKSQTRPELGKGCFTNIDPKIIDFWQTLTKQLRYSAQEEFEHLTNHLGHRPRAVEYY
HHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RAGYDLAKVNKQHGSWLELVASMDKDPELDYLVREHRDFFANAIQKASMTKSFKAILLEA
HCCCCHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLELDGFRDAPSIEVLASKSWHVLSRYPKLKASDLSEINQRLTADSQAWLKYWLSNPINA
HHHHCCCCCCCCEEEEECCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEE
FVGGNKTKNRVWFKLVDGKLKADFDVAPLQQQTFHDFVKELVDLQLAQYSDRPPKQTHQT
HCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VAQPTTPAEAANEGTLLPYYPNLKIACGHFKTGSHEEVEHIPVDMANLNPQKHFLARASG
HCCCCCCHHCCCCCCEEEECCCCEEEECCCCCCCCCCHHHCCCCHHCCCHHHHHEEECCC
NSMNGGKTPILDGDLLLLEFVTPISAGSITGNTMAIEIQDNSGENQYLLRVVQKDAQGRY
CCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCE
WLKANNPDYELMPANDSMKTFARLKKVITQ
EEEECCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412658 [H]