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The map label for this gene is tsr [C]

Identifier: 37680367

GI number: 37680367

Start: 2192869

End: 2194509

Strand: Direct

Name: tsr [C]

Synonym: VV2183

Alternate gene names: 37680367

Gene position: 2192869-2194509 (Clockwise)

Preceding gene: 37680356

Following gene: 37680375

Centisome position: 65.37

GC content: 48.81

Gene sequence:

>1641_bases
ATGCAATACCTTGCACAGTTAAAAGTAAGGACGCGTTTGGCGCTCGGTTTTGGTACGTTAGTGGCACTTATGGCATTACT
GACCATCGTCGGAATTCAAAAAGTTAACTTTATCGACATGAGCCTTGCTGAGGTGACGGACATTAACTCGGTAAAACAAC
GATACGCGATCAACTTTCGCGGCAGTGTTCATGATCGAGCTATCGCCATTCGCGATGTTGCAATGGCTCGAACCCCACAA
GAGCTTGCTCGTTTTGAAGATGAAATCCGTCGATTAGAAAAATTCTATCAACAATCGGAACAAAACATGCAAAGCATGAT
GGCTGATGGCATTCCCTTTTCAGCGCAAGAGCGAGCCATTTTGCAGCGCATTGGTGATATACAAACAAAAACGCTGCCTC
TTGTGAGAGAAGTGATAGCAAAGAAAAAGAGTGGCGAAGACGTTACCCCTATGCTGCTTGAGCAAGTTCGTCCAAGCTTC
GCCAACTGGTTAAAGGTGATCAATGAGTTTATTGATTATCAAGAGTCGCTCAACCAGCAACTGACGCCCATCGCTCGTGC
GGAGGCCAACGGATTTCAGAGCTTAATGCTGGTGCTAAGTGGTATCGCCGTGCTGATTTCGGCGATGGTTGGTTTCATTA
TTGAGCGCAGTTTTCGCCTCTCATTGGGGAGTGAACCTTATGTGGCTCAACATGCGATTCAGTTGATGGCCAATGGCGAG
TTAACTCAACAATATCAGAGCAGTGACCAAGGCAGTATTCTGCACTCACTTTCGTTGATGTCCGATAAACTCAGCTCTAT
CGTGCACAATATCCGAAACGCATCAGAGCAACTGGCCACCCAAGTGGAAGCCGTTTCAAGCGGTTCCAGTTCGGTCTTTG
ACTCCGCTCAGCAACAAGCATCGCTGACACAAAACATGGCCACAAAATTAGAAAGCATGCACGCCAGCATTGATGAGATT
GCCAAAGTGGTGAGCCTTACTGAGCAAAACTCAGTCAATACCTCGGATAATGCCCGTGATGGCCGCGTGCTTGTGGCGGC
AGTAGCGGAGCAAATGCTGTCTGTGACAGTCGCCGTCAATGAAACGGTTGCTCAGGTCAAACAGCTAGAAGCCAAAACGC
GCGATATTGGCGGAATCGTCAATATGATCAGCAGTATCTCAGAGCAAACCAACTTGCTCGCGCTGAATGCTGCGATAGAA
GCGGCGCGAGCGGGTGAATCTGGGCGCGGCTTTGCCGTTGTGGCAGATGAGGTACGAAGCCTAGCCAAACGTACAGGCGA
AGCAACAACGCAGATCGAGGCGATGCTCAAAGAAGTGCAAGCTCAAACCGTTGCCAGCGTGAGCGCAATGGAAAACACAC
AGCCTAAAGTAGAGAGTTGTCAGAAAAATACCGCACAAGCGAGCCAACTGCTGGTAAGCATTGAGCAGCAGTCTCAAGAT
TCTCTCAACCGAGTGCGTGACGTTGTCATCGCAACGGATGAACAAGTGGAAGTGGTCCGTGAGCTCGTCGTGGCCATGGA
ACAGATATCCTGCATGTCGAAGGAGTCCATTCGATCAATGGAGAATAACCAGGTGGCCAGTCAGAACTTGAACGCGCTTT
CTGATCATCTCAAACAAGAAGTTGCCTTCTTTAAAGTGTAA

Upstream 100 bases:

>100_bases
TTGCTCGAATAAAGCGGTCTCACTCTTTCCACAAAAACTAAAAAATAGGCGTTGTTGGCGACATTGCCTCAACGGTTACG
TTTGCTATCAGGAGTATGGA

Downstream 100 bases:

>100_bases
CGGTCAACGAATACTTGGCCGACAAAAAGTAAAAACTCAATCTGTCACCAGGTTGAGTTTTTAAAGCATTAGGCGTTGTT
TCAAATGCACCGCATTGCCC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MQYLAQLKVRTRLALGFGTLVALMALLTIVGIQKVNFIDMSLAEVTDINSVKQRYAINFRGSVHDRAIAIRDVAMARTPQ
ELARFEDEIRRLEKFYQQSEQNMQSMMADGIPFSAQERAILQRIGDIQTKTLPLVREVIAKKKSGEDVTPMLLEQVRPSF
ANWLKVINEFIDYQESLNQQLTPIARAEANGFQSLMLVLSGIAVLISAMVGFIIERSFRLSLGSEPYVAQHAIQLMANGE
LTQQYQSSDQGSILHSLSLMSDKLSSIVHNIRNASEQLATQVEAVSSGSSSVFDSAQQQASLTQNMATKLESMHASIDEI
AKVVSLTEQNSVNTSDNARDGRVLVAAVAEQMLSVTVAVNETVAQVKQLEAKTRDIGGIVNMISSISEQTNLLALNAAIE
AARAGESGRGFAVVADEVRSLAKRTGEATTQIEAMLKEVQAQTVASVSAMENTQPKVESCQKNTAQASQLLVSIEQQSQD
SLNRVRDVVIATDEQVEVVRELVVAMEQISCMSKESIRSMENNQVASQNLNALSDHLKQEVAFFKV

Sequences:

>Translated_546_residues
MQYLAQLKVRTRLALGFGTLVALMALLTIVGIQKVNFIDMSLAEVTDINSVKQRYAINFRGSVHDRAIAIRDVAMARTPQ
ELARFEDEIRRLEKFYQQSEQNMQSMMADGIPFSAQERAILQRIGDIQTKTLPLVREVIAKKKSGEDVTPMLLEQVRPSF
ANWLKVINEFIDYQESLNQQLTPIARAEANGFQSLMLVLSGIAVLISAMVGFIIERSFRLSLGSEPYVAQHAIQLMANGE
LTQQYQSSDQGSILHSLSLMSDKLSSIVHNIRNASEQLATQVEAVSSGSSSVFDSAQQQASLTQNMATKLESMHASIDEI
AKVVSLTEQNSVNTSDNARDGRVLVAAVAEQMLSVTVAVNETVAQVKQLEAKTRDIGGIVNMISSISEQTNLLALNAAIE
AARAGESGRGFAVVADEVRSLAKRTGEATTQIEAMLKEVQAQTVASVSAMENTQPKVESCQKNTAQASQLLVSIEQQSQD
SLNRVRDVVIATDEQVEVVRELVVAMEQISCMSKESIRSMENNQVASQNLNALSDHLKQEVAFFKV
>Mature_546_residues
MQYLAQLKVRTRLALGFGTLVALMALLTIVGIQKVNFIDMSLAEVTDINSVKQRYAINFRGSVHDRAIAIRDVAMARTPQ
ELARFEDEIRRLEKFYQQSEQNMQSMMADGIPFSAQERAILQRIGDIQTKTLPLVREVIAKKKSGEDVTPMLLEQVRPSF
ANWLKVINEFIDYQESLNQQLTPIARAEANGFQSLMLVLSGIAVLISAMVGFIIERSFRLSLGSEPYVAQHAIQLMANGE
LTQQYQSSDQGSILHSLSLMSDKLSSIVHNIRNASEQLATQVEAVSSGSSSVFDSAQQQASLTQNMATKLESMHASIDEI
AKVVSLTEQNSVNTSDNARDGRVLVAAVAEQMLSVTVAVNETVAQVKQLEAKTRDIGGIVNMISSISEQTNLLALNAAIE
AARAGESGRGFAVVADEVRSLAKRTGEATTQIEAMLKEVQAQTVASVSAMENTQPKVESCQKNTAQASQLLVSIEQQSQD
SLNRVRDVVIATDEQVEVVRELVVAMEQISCMSKESIRSMENNQVASQNLNALSDHLKQEVAFFKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=403, Percent_Identity=27.7915632754342, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787690, Length=360, Percent_Identity=26.3888888888889, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788194, Length=306, Percent_Identity=28.4313725490196, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788195, Length=191, Percent_Identity=32.9842931937173, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789453, Length=368, Percent_Identity=29.6195652173913, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59897; Mature: 59897

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLAQLKVRTRLALGFGTLVALMALLTIVGIQKVNFIDMSLAEVTDINSVKQRYAINFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCC
GSVHDRAIAIRDVAMARTPQELARFEDEIRRLEKFYQQSEQNMQSMMADGIPFSAQERAI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LQRIGDIQTKTLPLVREVIAKKKSGEDVTPMLLEQVRPSFANWLKVINEFIDYQESLNQQ
HHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LTPIARAEANGFQSLMLVLSGIAVLISAMVGFIIERSFRLSLGSEPYVAQHAIQLMANGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
LTQQYQSSDQGSILHSLSLMSDKLSSIVHNIRNASEQLATQVEAVSSGSSSVFDSAQQQA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SLTQNMATKLESMHASIDEIAKVVSLTEQNSVNTSDNARDGRVLVAAVAEQMLSVTVAVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ETVAQVKQLEAKTRDIGGIVNMISSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LAKRTGEATTQIEAMLKEVQAQTVASVSAMENTQPKVESCQKNTAQASQLLVSIEQQSQD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNRVRDVVIATDEQVEVVRELVVAMEQISCMSKESIRSMENNQVASQNLNALSDHLKQE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VAFFKV
HHHHCC
>Mature Secondary Structure
MQYLAQLKVRTRLALGFGTLVALMALLTIVGIQKVNFIDMSLAEVTDINSVKQRYAINFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCC
GSVHDRAIAIRDVAMARTPQELARFEDEIRRLEKFYQQSEQNMQSMMADGIPFSAQERAI
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LQRIGDIQTKTLPLVREVIAKKKSGEDVTPMLLEQVRPSFANWLKVINEFIDYQESLNQQ
HHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LTPIARAEANGFQSLMLVLSGIAVLISAMVGFIIERSFRLSLGSEPYVAQHAIQLMANGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCH
LTQQYQSSDQGSILHSLSLMSDKLSSIVHNIRNASEQLATQVEAVSSGSSSVFDSAQQQA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SLTQNMATKLESMHASIDEIAKVVSLTEQNSVNTSDNARDGRVLVAAVAEQMLSVTVAVN
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ETVAQVKQLEAKTRDIGGIVNMISSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LAKRTGEATTQIEAMLKEVQAQTVASVSAMENTQPKVESCQKNTAQASQLLVSIEQQSQD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLNRVRDVVIATDEQVEVVRELVVAMEQISCMSKESIRSMENNQVASQNLNALSDHLKQE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VAFFKV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA