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The map label for this gene is ppsA [H]

Identifier: 37521554

GI number: 37521554

Start: 2131300

End: 2133741

Strand: Reverse

Name: ppsA [H]

Synonym: gll1985

Alternate gene names: 37521554

Gene position: 2133741-2131300 (Counterclockwise)

Preceding gene: 37521558

Following gene: 37521553

Centisome position: 45.8

GC content: 65.48

Gene sequence:

>2442_bases
ATGCTGCAGGTTGAGCGACACGATTCCCAGCGCCGGTTGCATCGCGATCGGGCTCTGGTGTTGCGCTTGGGTGAGGTGGG
CCTTGCCGACATCGACAAAGTCGGGGGCAAGAACGCCTCTTTGGGTGAGCTGCTCCGCCAGTTGAGCGCCGAGGGCATTC
GTGTGCCGGAAGGATTTGCCGTCACCGCCTTTGCCTATCGCGAATTTATTGCCCACAACGGCCTGGAAGCCAAGTTGCGC
GCCCTGTTTGCGGGTCTGGACACGGAGGATATCGAACAGTTGCGCCGTGTGGGCGAGCAGGCGCGCGGGCTGGTGCTCGC
CTCGTCTCTGCCGGAGCGTTTGCAGGAGCGCATCCGGGAAGGCTATGGCGAGCTGTGCGGGCGTTACGGGGCGGACACCG
ACGTGGCGGTGCGCTCCAGCGCCACCGCCGAGGATTTGCCCGAGGCGAGTTTTGCCGGTCAGCAGGAGACCTATCTGGGA
GTGCAGGGCGAGGAGGCAGTACTCGAAGCCTGCAAGCGCTGTTACGCATCGCTGTTTACCGACCGGGCCATCTCCTACCG
GCAGTTGATGGGATTCGATCACTTCGAAGTGGCCCTTTCGGTGTGCATCCAGAAGATGGTCCGATCGGACCTGGCGGGTG
CCGGGGTGATGTTTTCAATTGACCCGGAGACGGGGTTTGCGAACGTTGTGCACATCGCCGCCGGTTGGGGCCTGGGCGAA
CTGGTGGTGCAGGGTGCTGTCAACCCGGATGAGTACGTCGTCTTCAAGCCGACGCTGGAGCGAGGATTTTTTCCCATCCT
CGCCAAGCGCCCCGGCAGCAAGGAGCGCAAGCTCGTCTACAGCGAGACCGGTCCGATCACCGTCGAGACCTCCCCCGCCG
AGCGGTCGGGTTTTGTGCTCGAAGAGGCCGAAATTCTCGAACTGGCCCGGTGGGCGGTGCTCATTGAGCGGCACTACAGC
CGGGTGCGCGGGGTGAACACCCCGATGGATATCGAATGGGCCAAAGATGGCCGCACGGGGGAGCTGTTCATCGTGCAGGC
CCGTCCCGAGACGGTGCAGTCGCACAAAAGCGCCCAGACCCTGGTGCACTGGCGCCTGAAGGGCAGTGCCCCGGTGCTCG
CCACGGGCCGCGCGGTCGGGGAGGGCGTCGGCCAGGGCCGCGCCCGGGTGATCCGCGATCCGAGTCAGCTCGAAGCTTTC
GAAAAAGGCGAAGTGCTGGTCACCGACCGCACCGACCCGGACTGGGAACCGATCATGAAAAAGGCGGGCGCCATCGTCAC
CAACCAGGGCGGACGCACCTGCCACGCCGCGATCATCGCCCGCGAACTGGGCATCCCGGCCATCGTCGGCACCGGGGAGG
CCACCCGCCGCATCGAGACCGGCGACCCGGTCACCGTCGCCTGCTGCGAGGGCGAGGAGGGTCGGGTCTACGCCGGGGAA
GTACCCTACGAGCGCACGGAGGTCGCCATCGACGCCCTGCCCCGGCCGCACACCCGGATACTGCTCAACGTCGGCAACCC
GGCGGAAGCCTTTCGCCTCGCCGCCATTCCCAACGACGGCGTCGGTCTGGCACGGCTGGAATTTATCATCGCCAACCACA
TCCAGGTGCATCCGTTGGCGCTGTTGCACTTCGAGCAACTCCCCGAGGGCGACGAAAAAGCGCGCCTGAGCGCCCTCACC
GAGGGCTATCCCGACCGGGCCGAGTACTTCGTCGAACACCTGGCGCGGGGGGTGGCGACCATCGCCGCCGCCTTTTATCC
CCAGCCGGTGATCGTGCGTCTGTCGGATTTTAAGTCCAACGAGTACGCGAACTTGTTGGGCGGGCGGCACTTCGAGCCGC
TCGAAGAAAACCCGATGCTGGGCTGGCGGGGCGCCTCGCGCTACTACGACGAGCGCTACCGCGCCGCCTTTGCCCTCGAA
TGCCGCGCCCTGAGATGGGTGCGCGACCAGATGGGGTTTACCAACGTCGTGGTGATGGTGCCTTTTTGCCGTACCCCCGA
AGAAGGCCGCCGGGTGATTGCCGAGATGGCGAGCCACGGCCTGGTGCGCGGTGAAAACGGCCTGGAAGTCTACGTGATGT
GCGAATTGCCGAGCAACGTCGTCCTTGCGGGCGAATTTGCCCAGGTCTTCGACGGATTTTCGATCGGCTCGAACGACCTC
ACGCAACTCACCCTTGGTCTCGACCGCGACTCGGCCGGGGTGGCGGGCCTGTTCGACGAGCGCCACCCGGCGGTCAGGAA
GATGGTGGCGATGGCCATCGAGGGCGCCCATGCCGCCAGGCGCAAAATCGGCATCTGCGGCCAGGCTCCGAGCGACTACC
CCGAATTTGCCCGTTTCTTAGTGGAACGGGGCATCGACTCGCTGAGCCTCAATCCCGACGCCGCCCTCAAGACGCGGCTT
CTGGTGGCCCGTGTCGAGGAGGAACTCTCCCGGCCGTCCTGA

Upstream 100 bases:

>100_bases
TTTCAGTTGTTTTTGCGACTGCAGTACAAAGATTTTGCTGTTCGATTCGGTGGTTCGGTGGAGTGGCCGTCGCGCCTTGG
GTCAATTTGGGAGGATTTTC

Downstream 100 bases:

>100_bases
CCGGGTGCGCAACCGCGCTCCCGGGAGGATACTGGCGCCTGGAACCGCCCTTTGTCGTTACAGGATGGATCCTATGCAAA
AAATCCTGGCTGCCTTCGAT

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 813; Mature: 813

Protein sequence:

>813_residues
MLQVERHDSQRRLHRDRALVLRLGEVGLADIDKVGGKNASLGELLRQLSAEGIRVPEGFAVTAFAYREFIAHNGLEAKLR
ALFAGLDTEDIEQLRRVGEQARGLVLASSLPERLQERIREGYGELCGRYGADTDVAVRSSATAEDLPEASFAGQQETYLG
VQGEEAVLEACKRCYASLFTDRAISYRQLMGFDHFEVALSVCIQKMVRSDLAGAGVMFSIDPETGFANVVHIAAGWGLGE
LVVQGAVNPDEYVVFKPTLERGFFPILAKRPGSKERKLVYSETGPITVETSPAERSGFVLEEAEILELARWAVLIERHYS
RVRGVNTPMDIEWAKDGRTGELFIVQARPETVQSHKSAQTLVHWRLKGSAPVLATGRAVGEGVGQGRARVIRDPSQLEAF
EKGEVLVTDRTDPDWEPIMKKAGAIVTNQGGRTCHAAIIARELGIPAIVGTGEATRRIETGDPVTVACCEGEEGRVYAGE
VPYERTEVAIDALPRPHTRILLNVGNPAEAFRLAAIPNDGVGLARLEFIIANHIQVHPLALLHFEQLPEGDEKARLSALT
EGYPDRAEYFVEHLARGVATIAAAFYPQPVIVRLSDFKSNEYANLLGGRHFEPLEENPMLGWRGASRYYDERYRAAFALE
CRALRWVRDQMGFTNVVVMVPFCRTPEEGRRVIAEMASHGLVRGENGLEVYVMCELPSNVVLAGEFAQVFDGFSIGSNDL
TQLTLGLDRDSAGVAGLFDERHPAVRKMVAMAIEGAHAARRKIGICGQAPSDYPEFARFLVERGIDSLSLNPDAALKTRL
LVARVEEELSRPS

Sequences:

>Translated_813_residues
MLQVERHDSQRRLHRDRALVLRLGEVGLADIDKVGGKNASLGELLRQLSAEGIRVPEGFAVTAFAYREFIAHNGLEAKLR
ALFAGLDTEDIEQLRRVGEQARGLVLASSLPERLQERIREGYGELCGRYGADTDVAVRSSATAEDLPEASFAGQQETYLG
VQGEEAVLEACKRCYASLFTDRAISYRQLMGFDHFEVALSVCIQKMVRSDLAGAGVMFSIDPETGFANVVHIAAGWGLGE
LVVQGAVNPDEYVVFKPTLERGFFPILAKRPGSKERKLVYSETGPITVETSPAERSGFVLEEAEILELARWAVLIERHYS
RVRGVNTPMDIEWAKDGRTGELFIVQARPETVQSHKSAQTLVHWRLKGSAPVLATGRAVGEGVGQGRARVIRDPSQLEAF
EKGEVLVTDRTDPDWEPIMKKAGAIVTNQGGRTCHAAIIARELGIPAIVGTGEATRRIETGDPVTVACCEGEEGRVYAGE
VPYERTEVAIDALPRPHTRILLNVGNPAEAFRLAAIPNDGVGLARLEFIIANHIQVHPLALLHFEQLPEGDEKARLSALT
EGYPDRAEYFVEHLARGVATIAAAFYPQPVIVRLSDFKSNEYANLLGGRHFEPLEENPMLGWRGASRYYDERYRAAFALE
CRALRWVRDQMGFTNVVVMVPFCRTPEEGRRVIAEMASHGLVRGENGLEVYVMCELPSNVVLAGEFAQVFDGFSIGSNDL
TQLTLGLDRDSAGVAGLFDERHPAVRKMVAMAIEGAHAARRKIGICGQAPSDYPEFARFLVERGIDSLSLNPDAALKTRL
LVARVEEELSRPS
>Mature_813_residues
MLQVERHDSQRRLHRDRALVLRLGEVGLADIDKVGGKNASLGELLRQLSAEGIRVPEGFAVTAFAYREFIAHNGLEAKLR
ALFAGLDTEDIEQLRRVGEQARGLVLASSLPERLQERIREGYGELCGRYGADTDVAVRSSATAEDLPEASFAGQQETYLG
VQGEEAVLEACKRCYASLFTDRAISYRQLMGFDHFEVALSVCIQKMVRSDLAGAGVMFSIDPETGFANVVHIAAGWGLGE
LVVQGAVNPDEYVVFKPTLERGFFPILAKRPGSKERKLVYSETGPITVETSPAERSGFVLEEAEILELARWAVLIERHYS
RVRGVNTPMDIEWAKDGRTGELFIVQARPETVQSHKSAQTLVHWRLKGSAPVLATGRAVGEGVGQGRARVIRDPSQLEAF
EKGEVLVTDRTDPDWEPIMKKAGAIVTNQGGRTCHAAIIARELGIPAIVGTGEATRRIETGDPVTVACCEGEEGRVYAGE
VPYERTEVAIDALPRPHTRILLNVGNPAEAFRLAAIPNDGVGLARLEFIIANHIQVHPLALLHFEQLPEGDEKARLSALT
EGYPDRAEYFVEHLARGVATIAAAFYPQPVIVRLSDFKSNEYANLLGGRHFEPLEENPMLGWRGASRYYDERYRAAFALE
CRALRWVRDQMGFTNVVVMVPFCRTPEEGRRVIAEMASHGLVRGENGLEVYVMCELPSNVVLAGEFAQVFDGFSIGSNDL
TQLTLGLDRDSAGVAGLFDERHPAVRKMVAMAIEGAHAARRKIGICGQAPSDYPEFARFLVERGIDSLSLNPDAALKTRL
LVARVEEELSRPS

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=795, Percent_Identity=53.3333333333333, Blast_Score=838, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=399, Percent_Identity=26.8170426065163, Blast_Score=123, Evalue=5e-29,
Organism=Escherichia coli, GI1789193, Length=411, Percent_Identity=25.7907542579075, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1788726, Length=404, Percent_Identity=25.7425742574257, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994992, Length=373, Percent_Identity=26.8096514745308, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564524, Length=222, Percent_Identity=32.8828828828829, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 89372; Mature: 89372

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVERHDSQRRLHRDRALVLRLGEVGLADIDKVGGKNASLGELLRQLSAEGIRVPEGFA
CCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCE
VTAFAYREFIAHNGLEAKLRALFAGLDTEDIEQLRRVGEQARGLVLASSLPERLQERIRE
EHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
GYGELCGRYGADTDVAVRSSATAEDLPEASFAGQQETYLGVQGEEAVLEACKRCYASLFT
HHHHHHHCCCCCCCEEEECCCCHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
DRAISYRQLMGFDHFEVALSVCIQKMVRSDLAGAGVMFSIDPETGFANVVHIAAGWGLGE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHH
LVVQGAVNPDEYVVFKPTLERGFFPILAKRPGSKERKLVYSETGPITVETSPAERSGFVL
HHHCCCCCCCCEEEECCCHHCCCEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCEE
EEAEILELARWAVLIERHYSRVRGVNTPMDIEWAKDGRTGELFIVQARPETVQSHKSAQT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHEE
LVHWRLKGSAPVLATGRAVGEGVGQGRARVIRDPSQLEAFEKGEVLVTDRTDPDWEPIMK
EEEEEECCCCCEEECCCHHHCCCCCCCCEEECCHHHHHHHCCCCEEEECCCCCCHHHHHH
KAGAIVTNQGGRTCHAAIIARELGIPAIVGTGEATRRIETGDPVTVACCEGEEGRVYAGE
HCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCHHCEECCCCCEEEEEECCCCCCEEECC
VPYERTEVAIDALPRPHTRILLNVGNPAEAFRLAAIPNDGVGLARLEFIIANHIQVHPLA
CCCCHHHHHEECCCCCCEEEEEECCCCHHHEEEEECCCCCCCHHHHHHHHHCCCEECHHH
LLHFEQLPEGDEKARLSALTEGYPDRAEYFVEHLARGVATIAAAFYPQPVIVRLSDFKSN
HHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
EYANLLGGRHFEPLEENPMLGWRGASRYYDERYRAAFALECRALRWVRDQMGFTNVVVMV
CHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PFCRTPEEGRRVIAEMASHGLVRGENGLEVYVMCELPSNVVLAGEFAQVFDGFSIGSNDL
ECCCCCHHHHHHHHHHHHCCCEECCCCCEEEEEEECCCCEEEECCHHHHHCCCCCCCCCC
TQLTLGLDRDSAGVAGLFDERHPAVRKMVAMAIEGAHAARRKIGICGQAPSDYPEFARFL
EEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHH
VERGIDSLSLNPDAALKTRLLVARVEEELSRPS
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQVERHDSQRRLHRDRALVLRLGEVGLADIDKVGGKNASLGELLRQLSAEGIRVPEGFA
CCCCCCCCHHHHHHHHHEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCE
VTAFAYREFIAHNGLEAKLRALFAGLDTEDIEQLRRVGEQARGLVLASSLPERLQERIRE
EHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHH
GYGELCGRYGADTDVAVRSSATAEDLPEASFAGQQETYLGVQGEEAVLEACKRCYASLFT
HHHHHHHCCCCCCCEEEECCCCHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHH
DRAISYRQLMGFDHFEVALSVCIQKMVRSDLAGAGVMFSIDPETGFANVVHIAAGWGLGE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCHHH
LVVQGAVNPDEYVVFKPTLERGFFPILAKRPGSKERKLVYSETGPITVETSPAERSGFVL
HHHCCCCCCCCEEEECCCHHCCCEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCEE
EEAEILELARWAVLIERHYSRVRGVNTPMDIEWAKDGRTGELFIVQARPETVQSHKSAQT
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHEE
LVHWRLKGSAPVLATGRAVGEGVGQGRARVIRDPSQLEAFEKGEVLVTDRTDPDWEPIMK
EEEEEECCCCCEEECCCHHHCCCCCCCCEEECCHHHHHHHCCCCEEEECCCCCCHHHHHH
KAGAIVTNQGGRTCHAAIIARELGIPAIVGTGEATRRIETGDPVTVACCEGEEGRVYAGE
HCCCEEECCCCCCHHHHHHHHHCCCCEEEECCCHHCEECCCCCEEEEEECCCCCCEEECC
VPYERTEVAIDALPRPHTRILLNVGNPAEAFRLAAIPNDGVGLARLEFIIANHIQVHPLA
CCCCHHHHHEECCCCCCEEEEEECCCCHHHEEEEECCCCCCCHHHHHHHHHCCCEECHHH
LLHFEQLPEGDEKARLSALTEGYPDRAEYFVEHLARGVATIAAAFYPQPVIVRLSDFKSN
HHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
EYANLLGGRHFEPLEENPMLGWRGASRYYDERYRAAFALECRALRWVRDQMGFTNVVVMV
CHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
PFCRTPEEGRRVIAEMASHGLVRGENGLEVYVMCELPSNVVLAGEFAQVFDGFSIGSNDL
ECCCCCHHHHHHHHHHHHCCCEECCCCCEEEEEEECCCCEEEECCHHHHHCCCCCCCCCC
TQLTLGLDRDSAGVAGLFDERHPAVRKMVAMAIEGAHAARRKIGICGQAPSDYPEFARFL
EEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHH
VERGIDSLSLNPDAALKTRLLVARVEEELSRPS
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]