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The map label for this gene is 37521533

Identifier: 37521533

GI number: 37521533

Start: 2107088

End: 2108548

Strand: Reverse

Name: 37521533

Synonym: gll1964

Alternate gene names: NA

Gene position: 2108548-2107088 (Counterclockwise)

Preceding gene: 37521535

Following gene: 37521532

Centisome position: 45.26

GC content: 59.27

Gene sequence:

>1461_bases
GTGAAGCGCTGCAAGGTCGCTGTCATCGGCGGTGGAATAAGTGGGATCGTGACGGCTAAGTGTCTGCGGGATGACGGCCA
TCAAGTGACGCTGTATGAGAGCACCGACCAAGTCGGCGGCATTTGGGTGTATCGCAAAACCAGCGGCGGCACTTTCGAAT
CGGTTCGCTTTCAAAATTCCAAATATCTCTCGGCTTTCTCGGATTATCCGATGCCTGAGCAGATGTCCGATTTCCCCCAC
CACACCGAGATTCTCGCGTACTTGAACAGCTATGTAGACCATTTTCGACTGCGCGAGTGTATACGCCTAAATTGCCAAGT
CGAGAAGGTTTCGCGAAGCCGCGATCACTGGAAGGTGACGGTGAGTACGCCCGAGGGTGCGGCGAGCGAATCGTTCGACG
CCCTCGCCATTTGCAGCGGTGTATTTCGGGAGCCGCGCTGGCCAAATATACCGGGTGAGGCAGATTTCAAAGGCACCCTT
CTGCACGCGAAAGATTACAAAGAGCCGTCCATGTTCGCCAATAAGCGCGTCGTAGTGATGGGCAACGGTGCGAGCGGCGT
CGACATTGCCGTGCGGGCCACGGACTTTGCCCAGAAGGTGATCTGGAGCTTTCGGCGCAACAGCTGGTTGGTCCCGCGCT
ATTTTGCCGGCCGCCCCCTCGACTGCAATCTCAGCCGTCTCTATGCGCTCATTCCGGCCGGTGTGCGCAAATCGTTGTAC
AGCCGCAAGTTCGCCCCGATTTGGGAGGCGCATCGGCAGTGCAACCTGGAGCCTGCGTTTGGCCTGTTTGCTTCGATTCC
GAGTGCCAACGAGTTCGTCATCGACCTGGTCGCCAAAGGGGCGATCGAGACCAGGCCCACCATTGCCGGATTTAGCGGGC
AGCGGGTGCTCTTTACCGACGGCAGCAGCACCGAGGCGGACATTGTGATCTATGCCACCGGCTACGGGGTCAGCTTCCCG
TTTTTCGATGCGTCGGTGGTGCCGGTGCACAACGAAGGCACCGACCTCTACAAGCATGTCTTTCATCCGGATCTGCCCAA
TTGCGGTTTTATCGGGATCATCCGGGTGATCGGCGCGCTTTTGCCCTGCGCCGAGATGCAGGCGCGCTGGTTTTCGAAGG
TGCTGAGCGAACAGGTGCACCTGCCCGACACCGAGTCGATGCGCGCTGAAATCCAGCGGATGCGCGCCCAACAACAAAAA
GATTGGGTCGCAAGCGGTTATCGGTCCTTCCAGGTGCGGCAGGTGGAGTACACCGAGGAAATCGCCCGGCTCATCGACGC
TGTCCCCAAAGTCTGGAGGCACTGGCAGATCGCCTGGCAGTTGCTTACCGGGCCGATGCTGCCCACGCACTACCGGTTGG
ATGGTCCCAATCCCTGGAAGGGGGCCGAGGAATGGATCCGGCAGGTGCCCGATCTGATCAAAATTCCCCGTAACGCTTCC
GGGGTGGGAGTCGGGCGGTGA

Upstream 100 bases:

>100_bases
CAAAGTTGTTATAGCCAGGAAAGCTGAATGCTTTCTGAGGAGAGAGCCCATGGCGATTGATACAGGTTCGATGTTGATAT
CTTCGGCTCCCAAGGTCGCG

Downstream 100 bases:

>100_bases
GAAGGCGCAACGTCCTGGGGTTGTCGCTGCTGCTGCTGGTGGGAGGAGCCGGTAAACTCGCCGCCGTCGGGGCGACCAAA
ATCGCGTACAAGCCCTACAT

Product: dimethylaniline monoxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MKRCKVAVIGGGISGIVTAKCLRDDGHQVTLYESTDQVGGIWVYRKTSGGTFESVRFQNSKYLSAFSDYPMPEQMSDFPH
HTEILAYLNSYVDHFRLRECIRLNCQVEKVSRSRDHWKVTVSTPEGAASESFDALAICSGVFREPRWPNIPGEADFKGTL
LHAKDYKEPSMFANKRVVVMGNGASGVDIAVRATDFAQKVIWSFRRNSWLVPRYFAGRPLDCNLSRLYALIPAGVRKSLY
SRKFAPIWEAHRQCNLEPAFGLFASIPSANEFVIDLVAKGAIETRPTIAGFSGQRVLFTDGSSTEADIVIYATGYGVSFP
FFDASVVPVHNEGTDLYKHVFHPDLPNCGFIGIIRVIGALLPCAEMQARWFSKVLSEQVHLPDTESMRAEIQRMRAQQQK
DWVASGYRSFQVRQVEYTEEIARLIDAVPKVWRHWQIAWQLLTGPMLPTHYRLDGPNPWKGAEEWIRQVPDLIKIPRNAS
GVGVGR

Sequences:

>Translated_486_residues
MKRCKVAVIGGGISGIVTAKCLRDDGHQVTLYESTDQVGGIWVYRKTSGGTFESVRFQNSKYLSAFSDYPMPEQMSDFPH
HTEILAYLNSYVDHFRLRECIRLNCQVEKVSRSRDHWKVTVSTPEGAASESFDALAICSGVFREPRWPNIPGEADFKGTL
LHAKDYKEPSMFANKRVVVMGNGASGVDIAVRATDFAQKVIWSFRRNSWLVPRYFAGRPLDCNLSRLYALIPAGVRKSLY
SRKFAPIWEAHRQCNLEPAFGLFASIPSANEFVIDLVAKGAIETRPTIAGFSGQRVLFTDGSSTEADIVIYATGYGVSFP
FFDASVVPVHNEGTDLYKHVFHPDLPNCGFIGIIRVIGALLPCAEMQARWFSKVLSEQVHLPDTESMRAEIQRMRAQQQK
DWVASGYRSFQVRQVEYTEEIARLIDAVPKVWRHWQIAWQLLTGPMLPTHYRLDGPNPWKGAEEWIRQVPDLIKIPRNAS
GVGVGR
>Mature_486_residues
MKRCKVAVIGGGISGIVTAKCLRDDGHQVTLYESTDQVGGIWVYRKTSGGTFESVRFQNSKYLSAFSDYPMPEQMSDFPH
HTEILAYLNSYVDHFRLRECIRLNCQVEKVSRSRDHWKVTVSTPEGAASESFDALAICSGVFREPRWPNIPGEADFKGTL
LHAKDYKEPSMFANKRVVVMGNGASGVDIAVRATDFAQKVIWSFRRNSWLVPRYFAGRPLDCNLSRLYALIPAGVRKSLY
SRKFAPIWEAHRQCNLEPAFGLFASIPSANEFVIDLVAKGAIETRPTIAGFSGQRVLFTDGSSTEADIVIYATGYGVSFP
FFDASVVPVHNEGTDLYKHVFHPDLPNCGFIGIIRVIGALLPCAEMQARWFSKVLSEQVHLPDTESMRAEIQRMRAQQQK
DWVASGYRSFQVRQVEYTEEIARLIDAVPKVWRHWQIAWQLLTGPMLPTHYRLDGPNPWKGAEEWIRQVPDLIKIPRNAS
GVGVGR

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI221316672, Length=499, Percent_Identity=32.6653306613226, Blast_Score=259, Evalue=3e-69,
Organism=Homo sapiens, GI4503755, Length=492, Percent_Identity=31.9105691056911, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI4503757, Length=465, Percent_Identity=32.6881720430108, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI4503759, Length=489, Percent_Identity=30.0613496932515, Blast_Score=225, Evalue=8e-59,
Organism=Homo sapiens, GI50541965, Length=486, Percent_Identity=29.8353909465021, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI50541961, Length=486, Percent_Identity=29.8353909465021, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI221316674, Length=420, Percent_Identity=33.0952380952381, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI221316678, Length=224, Percent_Identity=33.4821428571429, Blast_Score=136, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI25145785, Length=487, Percent_Identity=33.6755646817248, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI25150462, Length=500, Percent_Identity=30, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17541300, Length=500, Percent_Identity=30.8, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17555726, Length=492, Percent_Identity=32.3170731707317, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17561948, Length=493, Percent_Identity=31.0344827586207, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI193202226, Length=210, Percent_Identity=31.9047619047619, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17506045, Length=210, Percent_Identity=31.4285714285714, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321970, Length=189, Percent_Identity=29.1005291005291, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921694, Length=438, Percent_Identity=23.5159817351598, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI19922866, Length=209, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 54740; Mature: 54740

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCKVAVIGGGISGIVTAKCLRDDGHQVTLYESTDQVGGIWVYRKTSGGTFESVRFQNS
CCCEEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCC
KYLSAFSDYPMPEQMSDFPHHTEILAYLNSYVDHFRLRECIRLNCQVEKVSRSRDHWKVT
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCEEEE
VSTPEGAASESFDALAICSGVFREPRWPNIPGEADFKGTLLHAKDYKEPSMFANKRVVVM
EECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCEEEEE
GNGASGVDIAVRATDFAQKVIWSFRRNSWLVPRYFAGRPLDCNLSRLYALIPAGVRKSLY
ECCCCCCEEEEEHHHHHHHHHHHHHCCCEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SRKFAPIWEAHRQCNLEPAFGLFASIPSANEFVIDLVAKGAIETRPTIAGFSGQRVLFTD
HCCCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEECCCCCEEEEEC
GSSTEADIVIYATGYGVSFPFFDASVVPVHNEGTDLYKHVFHPDLPNCGFIGIIRVIGAL
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LPCAEMQARWFSKVLSEQVHLPDTESMRAEIQRMRAQQQKDWVASGYRSFQVRQVEYTEE
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
IARLIDAVPKVWRHWQIAWQLLTGPMLPTHYRLDGPNPWKGAEEWIRQVPDLIKIPRNAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCHHHHCCCCCCC
GVGVGR
CCCCCC
>Mature Secondary Structure
MKRCKVAVIGGGISGIVTAKCLRDDGHQVTLYESTDQVGGIWVYRKTSGGTFESVRFQNS
CCCEEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCC
KYLSAFSDYPMPEQMSDFPHHTEILAYLNSYVDHFRLRECIRLNCQVEKVSRSRDHWKVT
HHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCEEEE
VSTPEGAASESFDALAICSGVFREPRWPNIPGEADFKGTLLHAKDYKEPSMFANKRVVVM
EECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCEEEEE
GNGASGVDIAVRATDFAQKVIWSFRRNSWLVPRYFAGRPLDCNLSRLYALIPAGVRKSLY
ECCCCCCEEEEEHHHHHHHHHHHHHCCCEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHH
SRKFAPIWEAHRQCNLEPAFGLFASIPSANEFVIDLVAKGAIETRPTIAGFSGQRVLFTD
HCCCCHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEECCCCCEEEEEC
GSSTEADIVIYATGYGVSFPFFDASVVPVHNEGTDLYKHVFHPDLPNCGFIGIIRVIGAL
CCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LPCAEMQARWFSKVLSEQVHLPDTESMRAEIQRMRAQQQKDWVASGYRSFQVRQVEYTEE
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
IARLIDAVPKVWRHWQIAWQLLTGPMLPTHYRLDGPNPWKGAEEWIRQVPDLIKIPRNAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHCHHHHCCCCCCC
GVGVGR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]