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The map label for this gene is pksE [H]

Identifier: 37521525

GI number: 37521525

Start: 2088488

End: 2090131

Strand: Reverse

Name: pksE [H]

Synonym: gll1956

Alternate gene names: 37521525

Gene position: 2090131-2088488 (Counterclockwise)

Preceding gene: 37521526

Following gene: 37521524

Centisome position: 44.86

GC content: 63.32

Gene sequence:

>1644_bases
ATGCCGATCTCTACAACGGTTTGTGACACCGATGTGCGCCATGCAGGCAGCGCGCCGAAGACCGGGCAGGTCTGGAGCGG
TCCTGCCGATGCGGTTGCCTTCGATGAACCCGGTATCCGCTCGATTTTGCGCGATAGCGACGTGCCCTGTTATGCCGTCC
GCCAACAAGGCCGGATCGGTCTGGCAAGAGGCGGGTCGTGGCTGAGGGCCGCCGACGAAGCCGATCTGCCGGAGGTGCTG
GCCTTTGTGCCGGCGATGTCTTTGCACTCCCTGGGCGATCCCGCTTTTCTGGCCGCCCATCGGGTCCGTTGTGCGTACAT
GACCGGGGCAATGGCCAACGCCATCGCCTCGGAGGAACTGGTGATCGCCGTGGGCCGGGCCGGTATGCTCGGCAGTTTCG
GGGCGGCCGGTCTGGTGCCGGATCGGATCGCTGCGGCGATCGGACGCATTCAGGCGGCGCTGCCGGAGGGACCCTACGCC
TTCAATTTGATCCACAGCCCCAGCGAACCGGCCCTGGAGGCGGGGGCGGTGCGGGTGTACCTCGAAGGTGGCGTGCGCAC
CGTCGAGGCGAGCGCCTACATCGATCTCACAGCCCAGATCGTTCACTACCGCGCGGCGGGGTTGGGGCTCGATCCGGCTG
GGTGCATCACGATTGCCAACCGGGTGATTGCGAAGGTTTCCCGCCGGGAAGTGGCGGGCCGCTTTCTGCAGCCGGCACCT
GAAGCTCTGCTGCGGCAACTGGTCGAGGCGGGTCGGATCTCGCCTTTGCAGGCGACCCTGGCGGGCAAAGTGCCGATGGC
GGACGACATCACCGTCGAGGCGGATTCCGGCGGCCACACCGACAACCGTGCCCTGGTGTGCCTGCTGCCTTCGATCCTGG
CGCAACGCGACGAGATCCAGGCACAACAGCGCTTTGCCCAGCCGACGCGCATCGGGGCAGCAGGCGGGATCGGCACGCCG
CAGGCCGTTCTGGCGGCCTTCGTGATGGGGGCGGCGTACGTCGTGACCGGCTCGGTCAACCAGGCCTGCGTCGAGGCGGG
TACCTCCGCCCACACCCGTGCCCTGCTGGCCAGGGCGGAGACGACCGATGTGACGATGGCCCCGGCGGCGGACATGTTCG
AGGTGGGGGTCAGACTGCAGGTGCTCAAACGCGAAACCTTGTTTGCGATGCGCGCCCAGAAACTCTACGAGTTGTACAAG
ACCTACGGCGCTCTCGAAGAAATCCCGGCCGCCGAAATTCAAAAACTCGAATCCCAAATTTTCAAAAAAAGCCTCGAACA
GATCTGGCAGGAAACCATTGCTTACTTCAGCCATCGCGATCCACAGCAAATCGAAAAAGCCGAGGGCAACCCCAGGCGCA
AAATGGCCCTGATCTTTCGCTGGTATCTGGGTCTTTCTTCGCGCTGGTCTAACCTCGGCGAAAAGGGTCGGGAGATGGAT
TACCAGATCTGGTGCGGGCCAGCGATGGGTGCCTTTAACGATTGGGTCAAAGGCACCTACCTGGGCGTGCCTGAAAATCG
CACAGTTGTCGATGTGGCTGGACAGTTGATGCTGGGAGCTGCTTTTTTGTACCGGGTGCAGCATTTAAGAAGCCAGGGTC
TTCAACTGCCGCCCGCTTACTGCCGGTACTTTCCTACGCGTTAG

Upstream 100 bases:

>100_bases
TCAGGCAATGGGGCGAAATTCTCCAGCTGCAGCTTGCCGCCGCTCAGCAGGTGCTCGACGCACCCGTCCAGGCCACGGAG
CACTCGTCAGGGAGCCGATA

Downstream 100 bases:

>100_bases
AGAAAGCAAACTATCTATTTTCTTGAGGTAGACTGCATGAACGCTCCACCGTATTCATTGGCTGCAAAAGAGCTGGCAAA
CGCGGAAGCATTGCAGGAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MPISTTVCDTDVRHAGSAPKTGQVWSGPADAVAFDEPGIRSILRDSDVPCYAVRQQGRIGLARGGSWLRAADEADLPEVL
AFVPAMSLHSLGDPAFLAAHRVRCAYMTGAMANAIASEELVIAVGRAGMLGSFGAAGLVPDRIAAAIGRIQAALPEGPYA
FNLIHSPSEPALEAGAVRVYLEGGVRTVEASAYIDLTAQIVHYRAAGLGLDPAGCITIANRVIAKVSRREVAGRFLQPAP
EALLRQLVEAGRISPLQATLAGKVPMADDITVEADSGGHTDNRALVCLLPSILAQRDEIQAQQRFAQPTRIGAAGGIGTP
QAVLAAFVMGAAYVVTGSVNQACVEAGTSAHTRALLARAETTDVTMAPAADMFEVGVRLQVLKRETLFAMRAQKLYELYK
TYGALEEIPAAEIQKLESQIFKKSLEQIWQETIAYFSHRDPQQIEKAEGNPRRKMALIFRWYLGLSSRWSNLGEKGREMD
YQIWCGPAMGAFNDWVKGTYLGVPENRTVVDVAGQLMLGAAFLYRVQHLRSQGLQLPPAYCRYFPTR

Sequences:

>Translated_547_residues
MPISTTVCDTDVRHAGSAPKTGQVWSGPADAVAFDEPGIRSILRDSDVPCYAVRQQGRIGLARGGSWLRAADEADLPEVL
AFVPAMSLHSLGDPAFLAAHRVRCAYMTGAMANAIASEELVIAVGRAGMLGSFGAAGLVPDRIAAAIGRIQAALPEGPYA
FNLIHSPSEPALEAGAVRVYLEGGVRTVEASAYIDLTAQIVHYRAAGLGLDPAGCITIANRVIAKVSRREVAGRFLQPAP
EALLRQLVEAGRISPLQATLAGKVPMADDITVEADSGGHTDNRALVCLLPSILAQRDEIQAQQRFAQPTRIGAAGGIGTP
QAVLAAFVMGAAYVVTGSVNQACVEAGTSAHTRALLARAETTDVTMAPAADMFEVGVRLQVLKRETLFAMRAQKLYELYK
TYGALEEIPAAEIQKLESQIFKKSLEQIWQETIAYFSHRDPQQIEKAEGNPRRKMALIFRWYLGLSSRWSNLGEKGREMD
YQIWCGPAMGAFNDWVKGTYLGVPENRTVVDVAGQLMLGAAFLYRVQHLRSQGLQLPPAYCRYFPTR
>Mature_546_residues
PISTTVCDTDVRHAGSAPKTGQVWSGPADAVAFDEPGIRSILRDSDVPCYAVRQQGRIGLARGGSWLRAADEADLPEVLA
FVPAMSLHSLGDPAFLAAHRVRCAYMTGAMANAIASEELVIAVGRAGMLGSFGAAGLVPDRIAAAIGRIQAALPEGPYAF
NLIHSPSEPALEAGAVRVYLEGGVRTVEASAYIDLTAQIVHYRAAGLGLDPAGCITIANRVIAKVSRREVAGRFLQPAPE
ALLRQLVEAGRISPLQATLAGKVPMADDITVEADSGGHTDNRALVCLLPSILAQRDEIQAQQRFAQPTRIGAAGGIGTPQ
AVLAAFVMGAAYVVTGSVNQACVEAGTSAHTRALLARAETTDVTMAPAADMFEVGVRLQVLKRETLFAMRAQKLYELYKT
YGALEEIPAAEIQKLESQIFKKSLEQIWQETIAYFSHRDPQQIEKAEGNPRRKMALIFRWYLGLSSRWSNLGEKGREMDY
QIWCGPAMGAFNDWVKGTYLGVPENRTVVDVAGQLMLGAAFLYRVQHLRSQGLQLPPAYCRYFPTR

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 58929; Mature: 58798

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPISTTVCDTDVRHAGSAPKTGQVWSGPADAVAFDEPGIRSILRDSDVPCYAVRQQGRIG
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHCCCCCEEEECCCCCEE
LARGGSWLRAADEADLPEVLAFVPAMSLHSLGDPAFLAAHRVRCAYMTGAMANAIASEEL
EECCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
VIAVGRAGMLGSFGAAGLVPDRIAAAIGRIQAALPEGPYAFNLIHSPSEPALEAGAVRVY
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEE
LEGGVRTVEASAYIDLTAQIVHYRAAGLGLDPAGCITIANRVIAKVSRREVAGRFLQPAP
EECCCEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EALLRQLVEAGRISPLQATLAGKVPMADDITVEADSGGHTDNRALVCLLPSILAQRDEIQ
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHEEHHHHHHHHHHHH
AQQRFAQPTRIGAAGGIGTPQAVLAAFVMGAAYVVTGSVNQACVEAGTSAHTRALLARAE
HHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHCCCCHHHHHHHHHCC
TTDVTMAPAADMFEVGVRLQVLKRETLFAMRAQKLYELYKTYGALEEIPAAEIQKLESQI
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FKKSLEQIWQETIAYFSHRDPQQIEKAEGNPRRKMALIFRWYLGLSSRWSNLGEKGREMD
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YQIWCGPAMGAFNDWVKGTYLGVPENRTVVDVAGQLMLGAAFLYRVQHLRSQGLQLPPAY
EEEEECCCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
CRYFPTR
HHCCCCC
>Mature Secondary Structure 
PISTTVCDTDVRHAGSAPKTGQVWSGPADAVAFDEPGIRSILRDSDVPCYAVRQQGRIG
CCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHHHHCCCCCEEEECCCCCEE
LARGGSWLRAADEADLPEVLAFVPAMSLHSLGDPAFLAAHRVRCAYMTGAMANAIASEEL
EECCCCHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
VIAVGRAGMLGSFGAAGLVPDRIAAAIGRIQAALPEGPYAFNLIHSPSEPALEAGAVRVY
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEE
LEGGVRTVEASAYIDLTAQIVHYRAAGLGLDPAGCITIANRVIAKVSRREVAGRFLQPAP
EECCCEEEECHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EALLRQLVEAGRISPLQATLAGKVPMADDITVEADSGGHTDNRALVCLLPSILAQRDEIQ
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHEEHHHHHHHHHHHH
AQQRFAQPTRIGAAGGIGTPQAVLAAFVMGAAYVVTGSVNQACVEAGTSAHTRALLARAE
HHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHEEECCCHHHHHHCCCCHHHHHHHHHCC
TTDVTMAPAADMFEVGVRLQVLKRETLFAMRAQKLYELYKTYGALEEIPAAEIQKLESQI
CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FKKSLEQIWQETIAYFSHRDPQQIEKAEGNPRRKMALIFRWYLGLSSRWSNLGEKGREMD
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YQIWCGPAMGAFNDWVKGTYLGVPENRTVVDVAGQLMLGAAFLYRVQHLRSQGLQLPPAY
EEEEECCCCCHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
CRYFPTR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]