Click here to switch to the map view.

The map label for this gene is hetI [H]

Identifier: 37521520

GI number: 37521520

Start: 2077916

End: 2078683

Strand: Reverse

Name: hetI [H]

Synonym: gll1951

Alternate gene names: 37521520

Gene position: 2078683-2077916 (Counterclockwise)

Preceding gene: 37521521

Following gene: 37521519

Centisome position: 44.62

GC content: 65.62

Gene sequence:

>768_bases
ATGGTCGCTATTGAAGCCCCGTGGCGGCCGACTGCCGCCCCGCCGGTGCTGACCCCGGCTGCGGTACACATCTGGCAGGC
GGATCTCGATTGGCCCGCCGCTCCGCTGCCGGTGCTGGAGCGCACCCTGTGCCCGCAGGAACGGAGCCGGGCGGAACGCT
TCTGCTTCGAGCAGCACCGCCGGCGCTTTATCGTCGGCCGCGCCACACTGCGGATGCTGCTGGGACTGTATCTGCAGAGC
GAACCGGCTTGCGTGCCAATCAGCTACGGAGCGCACGGCAAACCGCTGCTGGCCGACGGGGCGCACCCCTTGCGCTTCAA
TTTGTCCCACAGCCAGGGAAAGGCCGTCTACGCCTTCAGCTGCGGGCGGGAGGTCGGCGTCGATCTCGAATGGGATCGAC
CGCTCGCCAATTTCGATCAGCTTGCGCGTGTCGCTTTCTCCGAGGACGAAAACCGGGTATTCAAAGCCCTCGCGCCCTAC
CAGCGCCGCGCCGCTTTTTTTCGTTGCTGGACGCGCAAAGAGGCCTACGCCAAAGCCAGGGGATATGGCTTCGCACTCGC
TCCCGACCGCTACACAGTTTCGCTCGCACCGGACGCACCGGCAGCACTCCTGCAAAGTCGGGAGGAATCTGGAGAAGCCG
GGCGCTGGGTGCTGTTGGACCTGTTGCCCTGGCCGGATTATCCGGCAGCTCTGGCTGTGGAAGGTTCGAGCGGGCAGGTG
CACTGCTGGCACAGCCCGGAGCCGATTTCAAGGAGATCGCCGCGATGA

Upstream 100 bases:

>100_bases
TTCCGCAGGCAGCCCGCCGACAGCCCGTCCCCACCGGGCGGTTTCTCCACCCCGATGCGCACCGGCGACCCTTCGGCGCT
GGCTGGACCAGCCTCCCCCG

Downstream 100 bases:

>100_bases
ATCTTGCCTACATCCTGGACGAGGGGCTCGAAAATACGCCCCGCAAAACCCTCTTCACCGGCGACGGCCGCTCCTATACC
TACAACCAGGTGGTGCGCGC

Product: phosphopantetheinyltransferase family protein

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVAIEAPWRPTAAPPVLTPAAVHIWQADLDWPAAPLPVLERTLCPQERSRAERFCFEQHRRRFIVGRATLRMLLGLYLQS
EPACVPISYGAHGKPLLADGAHPLRFNLSHSQGKAVYAFSCGREVGVDLEWDRPLANFDQLARVAFSEDENRVFKALAPY
QRRAAFFRCWTRKEAYAKARGYGFALAPDRYTVSLAPDAPAALLQSREESGEAGRWVLLDLLPWPDYPAALAVEGSSGQV
HCWHSPEPISRRSPR

Sequences:

>Translated_255_residues
MVAIEAPWRPTAAPPVLTPAAVHIWQADLDWPAAPLPVLERTLCPQERSRAERFCFEQHRRRFIVGRATLRMLLGLYLQS
EPACVPISYGAHGKPLLADGAHPLRFNLSHSQGKAVYAFSCGREVGVDLEWDRPLANFDQLARVAFSEDENRVFKALAPY
QRRAAFFRCWTRKEAYAKARGYGFALAPDRYTVSLAPDAPAALLQSREESGEAGRWVLLDLLPWPDYPAALAVEGSSGQV
HCWHSPEPISRRSPR
>Mature_255_residues
MVAIEAPWRPTAAPPVLTPAAVHIWQADLDWPAAPLPVLERTLCPQERSRAERFCFEQHRRRFIVGRATLRMLLGLYLQS
EPACVPISYGAHGKPLLADGAHPLRFNLSHSQGKAVYAFSCGREVGVDLEWDRPLANFDQLARVAFSEDENRVFKALAPY
QRRAAFFRCWTRKEAYAKARGYGFALAPDRYTVSLAPDAPAALLQSREESGEAGRWVLLDLLPWPDYPAALAVEGSSGQV
HCWHSPEPISRRSPR

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Escherichia coli, GI1789886, Length=149, Percent_Identity=40.2684563758389, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 28583; Mature: 28583

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAIEAPWRPTAAPPVLTPAAVHIWQADLDWPAAPLPVLERTLCPQERSRAERFCFEQHR
CEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRFIVGRATLRMLLGLYLQSEPACVPISYGAHGKPLLADGAHPLRFNLSHSQGKAVYAFS
HEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEEECCCCCCEEEEEE
CGREVGVDLEWDRPLANFDQLARVAFSEDENRVFKALAPYQRRAAFFRCWTRKEAYAKAR
CCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
GYGFALAPDRYTVSLAPDAPAALLQSREESGEAGRWVLLDLLPWPDYPAALAVEGSSGQV
CCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCCE
HCWHSPEPISRRSPR
EEECCCCCCCCCCCC
>Mature Secondary Structure
MVAIEAPWRPTAAPPVLTPAAVHIWQADLDWPAAPLPVLERTLCPQERSRAERFCFEQHR
CEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHH
RRFIVGRATLRMLLGLYLQSEPACVPISYGAHGKPLLADGAHPLRFNLSHSQGKAVYAFS
HEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEEECCCCCCEEEEEE
CGREVGVDLEWDRPLANFDQLARVAFSEDENRVFKALAPYQRRAAFFRCWTRKEAYAKAR
CCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
GYGFALAPDRYTVSLAPDAPAALLQSREESGEAGRWVLLDLLPWPDYPAALAVEGSSGQV
CCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEECCCCCE
HCWHSPEPISRRSPR
EEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]