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The map label for this gene is ddpX [H]

Identifier: 37521493

GI number: 37521493

Start: 2045218

End: 2045895

Strand: Reverse

Name: ddpX [H]

Synonym: gll1924

Alternate gene names: 37521493

Gene position: 2045895-2045218 (Counterclockwise)

Preceding gene: 37521497

Following gene: 37521492

Centisome position: 43.91

GC content: 64.45

Gene sequence:

>678_bases
GTGGCGGCGCCCGGATTCCTGGAAGCGAGAAGCGCTCGGTATGATGTCCCCAAGGTTGTGGAGCCGCGAATTTTAGTGCA
ATGGTTTTTTGTGCTGTTGGCTTTGGCCGTCGTCCTGGTTTCGAAGCCGGTCTCGGCCGAGGCGATGGTGGATTTGGGTG
CCGTCGCTCCCGGAGTGCGCCGTGACATGCGCTACGCCACTGTGGACAATTTCCTCAAAAAGGCGGTCTACCCCGAGGCG
CGCTGTCTGTTGCGCCCCCCGGTGGCCGAGCGTCTAGCCCGGGTGCAAAACCGGCTGGCCGCTGAGGGATTTGGTCTCAA
AGTCTGGGACTGCTACCGGCCGCTTGCTGTGCAAAAGCAGATGTGGGCGCTGGTGCCCGACGAGCGCTACGTGGCCGACC
CCGCCAAGGGCTCCCGCCACAACCGCGGCGCGGCGGTGGATTTGACGCTTGTCGACAGCCGGGGCAAGGAGCAGGAGATG
CCCACGGCCTTCGACGACTTTTCTGCCGGAGCCGGCCGCGACGCCCAGGCCCAGTGGAGCGTAACAGCCAGACGCAACTA
TGCCGTTTTGCATAAGGCGATGATAGCGGAGGACTTTCTGCCGCTGCCCTCCGAGTGGTGGCACTACGACGCACCGGGAT
GGGAGCGGTACCCGGTGGTCGATCTCCCGCTGCGCTAG

Upstream 100 bases:

>100_bases
TTCCCATCTGGGGCACCTCTGGCCCCGAAGGTGTCAAGGCGACGGTCTGCATGCAATTACCCCCTGATAAAGTCCCCTTC
TCGAGGATATTTCAGAGGGG

Downstream 100 bases:

>100_bases
GTGGGCCATTGCTTAAATAATGTTGGATATTCCCCGATCCGAGCGCCCAGGTTGAGTATTTTCGGACCAAAGTTCTAAGC
AGGTACGTGTGAGTGAGCAG

Product: peptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAAPGFLEARSARYDVPKVVEPRILVQWFFVLLALAVVLVSKPVSAEAMVDLGAVAPGVRRDMRYATVDNFLKKAVYPEA
RCLLRPPVAERLARVQNRLAAEGFGLKVWDCYRPLAVQKQMWALVPDERYVADPAKGSRHNRGAAVDLTLVDSRGKEQEM
PTAFDDFSAGAGRDAQAQWSVTARRNYAVLHKAMIAEDFLPLPSEWWHYDAPGWERYPVVDLPLR

Sequences:

>Translated_225_residues
MAAPGFLEARSARYDVPKVVEPRILVQWFFVLLALAVVLVSKPVSAEAMVDLGAVAPGVRRDMRYATVDNFLKKAVYPEA
RCLLRPPVAERLARVQNRLAAEGFGLKVWDCYRPLAVQKQMWALVPDERYVADPAKGSRHNRGAAVDLTLVDSRGKEQEM
PTAFDDFSAGAGRDAQAQWSVTARRNYAVLHKAMIAEDFLPLPSEWWHYDAPGWERYPVVDLPLR
>Mature_224_residues
AAPGFLEARSARYDVPKVVEPRILVQWFFVLLALAVVLVSKPVSAEAMVDLGAVAPGVRRDMRYATVDNFLKKAVYPEAR
CLLRPPVAERLARVQNRLAAEGFGLKVWDCYRPLAVQKQMWALVPDERYVADPAKGSRHNRGAAVDLTLVDSRGKEQEMP
TAFDDFSAGAGRDAQAQWSVTARRNYAVLHKAMIAEDFLPLPSEWWHYDAPGWERYPVVDLPLR

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=174, Percent_Identity=36.2068965517241, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 25290; Mature: 25159

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPGFLEARSARYDVPKVVEPRILVQWFFVLLALAVVLVSKPVSAEAMVDLGAVAPGVR
CCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHH
RDMRYATVDNFLKKAVYPEARCLLRPPVAERLARVQNRLAAEGFGLKVWDCYRPLAVQKQ
HHHHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHHHHHHHHCCCCEEHHHHHCCHHHHHH
MWALVPDERYVADPAKGSRHNRGAAVDLTLVDSRGKEQEMPTAFDDFSAGAGRDAQAQWS
HHHCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEEE
VTARRNYAVLHKAMIAEDFLPLPSEWWHYDAPGWERYPVVDLPLR
EEHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEECCCC
>Mature Secondary Structure 
AAPGFLEARSARYDVPKVVEPRILVQWFFVLLALAVVLVSKPVSAEAMVDLGAVAPGVR
CCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHH
RDMRYATVDNFLKKAVYPEARCLLRPPVAERLARVQNRLAAEGFGLKVWDCYRPLAVQKQ
HHHHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHHHHHHHHCCCCEEHHHHHCCHHHHHH
MWALVPDERYVADPAKGSRHNRGAAVDLTLVDSRGKEQEMPTAFDDFSAGAGRDAQAQWS
HHHCCCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEEE
VTARRNYAVLHKAMIAEDFLPLPSEWWHYDAPGWERYPVVDLPLR
EEHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]