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The map label for this gene is tsf

Identifier: 37521398

GI number: 37521398

Start: 1947756

End: 1948415

Strand: Reverse

Name: tsf

Synonym: gvip250

Alternate gene names: 37521398

Gene position: 1948415-1947756 (Counterclockwise)

Preceding gene: 37521399

Following gene: 37521395

Centisome position: 41.82

GC content: 58.33

Gene sequence:

>660_bases
ATGGCTGAAATCACATCCCAAATGGTCATGCAACTGCGCGAGAAGACCCAGGTCGGCGTACTAGACTGCAAAAAGGCGCT
GGCTGAAGCCGAAGGCGATCTCGAAAAAGCGATCGAGCTGTTGCGCAAGAAGGGCATCATGAAGGCCGGCAAGGTCAAGG
ACAAAGTCGCCACCGAGGGACTGGTCGGTTCCTACATCCATACCGGCGGTCGTATCGGCGTGCTGGTGGAGGTCAACTGC
CAGACCGACTTCGTCGCCAAGGGCGAGGAGTTCCAGCAGCTGGTGCGCGACATCGCCATGCAGATCGCGGCAAGCCCGAA
TGTCGAGTTCGTCTCGGTCGACGATGTCGATCAAGAAGTCAAAGACCGCGAACTGGCCATCGAGGTGCAGCGCGAAGACT
TGCTCAGCAAGCCCGAAAAGATCCGCGCCCAGATTGCCCAGGGCCGGGTCGACAAGCTCTTCAAAGAGCGGGCGCTGTTG
GAGCAGCCTTTTATCAAGGACCAGTCGATCAGCGTCGGCGAACTGATCACCCAGAAGATCGCCAAGATTGGCGAAAATAT
CAAGGTGCGCCGCTTCGCGCGCTTTGTACTGGGCGAGGGCCTCGAAAAAGAAGAGAAGAACTTCGCTGAGGAAGTGGCTG
CCCAGACCGGCAGCGTCTGA

Upstream 100 bases:

>100_bases
CGGTGGCGGTGGCCGCTCCCGCCGAGGCGGAATCGGAAGATAAAGGCGAAGTGCTCTACTCGTTCGACGACGAAGAAGAA
TAACTGGCGAGGCAAACACC

Downstream 100 bases:

>100_bases
TCCGGCTTCAATTTTCAACAAGCCCGAGGCGAAAGCTGCGGGCTTTTTTATTGGCCCGGCTGATTTTTGATCAAGATTTC
GACGCGGCGGTTTTTCTGGC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAEITSQMVMQLREKTQVGVLDCKKALAEAEGDLEKAIELLRKKGIMKAGKVKDKVATEGLVGSYIHTGGRIGVLVEVNC
QTDFVAKGEEFQQLVRDIAMQIAASPNVEFVSVDDVDQEVKDRELAIEVQREDLLSKPEKIRAQIAQGRVDKLFKERALL
EQPFIKDQSISVGELITQKIAKIGENIKVRRFARFVLGEGLEKEEKNFAEEVAAQTGSV

Sequences:

>Translated_219_residues
MAEITSQMVMQLREKTQVGVLDCKKALAEAEGDLEKAIELLRKKGIMKAGKVKDKVATEGLVGSYIHTGGRIGVLVEVNC
QTDFVAKGEEFQQLVRDIAMQIAASPNVEFVSVDDVDQEVKDRELAIEVQREDLLSKPEKIRAQIAQGRVDKLFKERALL
EQPFIKDQSISVGELITQKIAKIGENIKVRRFARFVLGEGLEKEEKNFAEEVAAQTGSV
>Mature_218_residues
AEITSQMVMQLREKTQVGVLDCKKALAEAEGDLEKAIELLRKKGIMKAGKVKDKVATEGLVGSYIHTGGRIGVLVEVNCQ
TDFVAKGEEFQQLVRDIAMQIAASPNVEFVSVDDVDQEVKDRELAIEVQREDLLSKPEKIRAQIAQGRVDKLFKERALLE
QPFIKDQSISVGELITQKIAKIGENIKVRRFARFVLGEGLEKEEKNFAEEVAAQTGSV

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=193, Percent_Identity=30.5699481865285, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=41, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=41, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI171846268, Length=100, Percent_Identity=41, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786366, Length=94, Percent_Identity=53.1914893617021, Blast_Score=99, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561440, Length=203, Percent_Identity=26.1083743842365, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_GLOVI (Q7NJK3)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_924775.1
- ProteinModelPortal:   Q7NJK3
- SMR:   Q7NJK3
- GeneID:   2600231
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.1829
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- ProtClustDB:   PRK12332
- BioCyc:   GVIO251221:GLL1829-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 24326; Mature: 24195

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITSQMVMQLREKTQVGVLDCKKALAEAEGDLEKAIELLRKKGIMKAGKVKDKVATEG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCHHHHHHHHH
LVGSYIHTGGRIGVLVEVNCQTDFVAKGEEFQQLVRDIAMQIAASPNVEFVSVDDVDQEV
HHHHHHHCCCCEEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
KDRELAIEVQREDLLSKPEKIRAQIAQGRVDKLFKERALLEQPFIKDQSISVGELITQKI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AKIGENIKVRRFARFVLGEGLEKEEKNFAEEVAAQTGSV
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEITSQMVMQLREKTQVGVLDCKKALAEAEGDLEKAIELLRKKGIMKAGKVKDKVATEG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCHHHHHHHHH
LVGSYIHTGGRIGVLVEVNCQTDFVAKGEEFQQLVRDIAMQIAASPNVEFVSVDDVDQEV
HHHHHHHCCCCEEEEEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
KDRELAIEVQREDLLSKPEKIRAQIAQGRVDKLFKERALLEQPFIKDQSISVGELITQKI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AKIGENIKVRRFARFVLGEGLEKEEKNFAEEVAAQTGSV
HHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292