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The map label for this gene is murB [H]

Identifier: 37521349

GI number: 37521349

Start: 1894176

End: 1895015

Strand: Reverse

Name: murB [H]

Synonym: gll1780

Alternate gene names: 37521349

Gene position: 1895015-1894176 (Counterclockwise)

Preceding gene: 37521350

Following gene: 37521348

Centisome position: 40.67

GC content: 50.12

Gene sequence:

>840_bases
GTGGTGAGTATTGTTTCTGTCGAATCGAACCAACTTTCCACTTTTCGGACCACTCATCGATTTGAGTGTTACGGAGAATT
CAAAAGCGCCGAGGAATTTATGGACTACTGCCGGTGGGCAGACCGGCACGGAGCGAAGGTCTATATCCTCGGAAACGGCT
CCAATACTTTGTTCACTCGCTCGTCGGTGCGCTCGCTGGTGCTCAAGAATAGCTTGCCCAAAACCCTCGAACCGCTTCCC
GACTACCGCCTGCGGGTATCTTCCACCGTGCAGATCAACGAAGTATTGAACTACTGCGGCCAAAATTCTTTTGACAGCTT
TTACTATCTGGCTTCGGTTCCCGCTTCGATTGGCGGAGCGTTGGCAATGAACGCCGGTAGGGGCAAACTTCACAGCCGCA
CCATTTACGATTTTGTGGAAAGCGTGACGTTTCTTGAAAACGGCGAAGTCAAGACCCTCGCCAACGAGCAGATTACCAGA
AGCTATCGCCAAACTGTCTTCACCGGCATGACCCGCAAATTGATCTTGAGCGCTGTGCTGCAATTCAGCCCGGCGGATTT
TGCTTCCAACCCTCTGCAGGAACGTCGACAGTGGGCCAAAGAACACCAGGACAATACTCTGCCCAATTGCGGCACAGTCT
TTAAATCGGCTTGTTATCCAATCATGGACAGACTGCGGGGATTGCGTATCGGTGAAGCCTGGTTTTCCAGCAAAACCAGC
AACTGGATTTTAAACAAGTCGAAAAGCAGCACGCCGATAGTGACCTTGATTACGATAACCAAAATTTTGCACTTGATGGC
ACTGCAAAAGGTTGAATTAGAAGTGATCAGTGTGGACTAA

Upstream 100 bases:

>100_bases
TTGAGCGGGCGTTTGCCTACGCCCGCGAATTGTTGCCCAAAGCGGCGGGCAGCAAAGCGTCTTGATCGTATAGGTCGCGT
TCTTGCTTCAGGGAGTAACT

Downstream 100 bases:

>100_bases
GTTATCTCCTTTAAATTGACATGGTACTATCGGTTGGATAGCATAGCTTAAAGTCGGACACTAGCCAGGGAAGCTCGACA
ATGAAAGTAGGAATTCTCTC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MVSIVSVESNQLSTFRTTHRFECYGEFKSAEEFMDYCRWADRHGAKVYILGNGSNTLFTRSSVRSLVLKNSLPKTLEPLP
DYRLRVSSTVQINEVLNYCGQNSFDSFYYLASVPASIGGALAMNAGRGKLHSRTIYDFVESVTFLENGEVKTLANEQITR
SYRQTVFTGMTRKLILSAVLQFSPADFASNPLQERRQWAKEHQDNTLPNCGTVFKSACYPIMDRLRGLRIGEAWFSSKTS
NWILNKSKSSTPIVTLITITKILHLMALQKVELEVISVD

Sequences:

>Translated_279_residues
MVSIVSVESNQLSTFRTTHRFECYGEFKSAEEFMDYCRWADRHGAKVYILGNGSNTLFTRSSVRSLVLKNSLPKTLEPLP
DYRLRVSSTVQINEVLNYCGQNSFDSFYYLASVPASIGGALAMNAGRGKLHSRTIYDFVESVTFLENGEVKTLANEQITR
SYRQTVFTGMTRKLILSAVLQFSPADFASNPLQERRQWAKEHQDNTLPNCGTVFKSACYPIMDRLRGLRIGEAWFSSKTS
NWILNKSKSSTPIVTLITITKILHLMALQKVELEVISVD
>Mature_279_residues
MVSIVSVESNQLSTFRTTHRFECYGEFKSAEEFMDYCRWADRHGAKVYILGNGSNTLFTRSSVRSLVLKNSLPKTLEPLP
DYRLRVSSTVQINEVLNYCGQNSFDSFYYLASVPASIGGALAMNAGRGKLHSRTIYDFVESVTFLENGEVKTLANEQITR
SYRQTVFTGMTRKLILSAVLQFSPADFASNPLQERRQWAKEHQDNTLPNCGTVFKSACYPIMDRLRGLRIGEAWFSSKTS
NWILNKSKSSTPIVTLITITKILHLMALQKVELEVISVD

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 31538; Mature: 31538

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIVSVESNQLSTFRTTHRFECYGEFKSAEEFMDYCRWADRHGAKVYILGNGSNTLFTR
CEEEEEECCCCCHHHHHHHHHEEHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEH
SSVRSLVLKNSLPKTLEPLPDYRLRVSSTVQINEVLNYCGQNSFDSFYYLASVPASIGGA
HHHHHHHHHCCCCHHHCCCCCCEEEECCEEEHHHHHHHCCCCCCCCEEEEECCCHHHCCC
LAMNAGRGKLHSRTIYDFVESVTFLENGEVKTLANEQITRSYRQTVFTGMTRKLILSAVL
EEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFSPADFASNPLQERRQWAKEHQDNTLPNCGTVFKSACYPIMDRLRGLRIGEAWFSSKTS
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEECHHHHCCCCC
NWILNKSKSSTPIVTLITITKILHLMALQKVELEVISVD
CEEEECCCCCCCEEHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MVSIVSVESNQLSTFRTTHRFECYGEFKSAEEFMDYCRWADRHGAKVYILGNGSNTLFTR
CEEEEEECCCCCHHHHHHHHHEEHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEH
SSVRSLVLKNSLPKTLEPLPDYRLRVSSTVQINEVLNYCGQNSFDSFYYLASVPASIGGA
HHHHHHHHHCCCCHHHCCCCCCEEEECCEEEHHHHHHHCCCCCCCCEEEEECCCHHHCCC
LAMNAGRGKLHSRTIYDFVESVTFLENGEVKTLANEQITRSYRQTVFTGMTRKLILSAVL
EEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFSPADFASNPLQERRQWAKEHQDNTLPNCGTVFKSACYPIMDRLRGLRIGEAWFSSKTS
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEECHHHHCCCCC
NWILNKSKSSTPIVTLITITKILHLMALQKVELEVISVD
CEEEECCCCCCCEEHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]