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The map label for this gene is yuxL [H]

Identifier: 37521272

GI number: 37521272

Start: 1811597

End: 1813789

Strand: Reverse

Name: yuxL [H]

Synonym: gll1703

Alternate gene names: 37521272

Gene position: 1813789-1811597 (Counterclockwise)

Preceding gene: 37521273

Following gene: 37521271

Centisome position: 38.93

GC content: 63.84

Gene sequence:

>2193_bases
ATGGGATTGAAATGTCTTTGCCGGCGTGCCGTCCTGGCTGCCGCCCTTTTTGTCTGCTGCGCCGGTTTTGCCGTTCCCTT
GCCGGGGATTGCCGCCGAGTCCAAACGGCCGATCACCGAAAAAGATTTGCTCAAATTCAACTGGGTCGCCGACCCGCGCC
TATCGCCCGACGGCGCGCGCGTCGTCTATGTGCGGGTGAGCGTCGACGAGAAAAAGGACACTTACACCACTTCCCTCTGG
CAGGTTGCGACCGCCACCGGCGAGGCGCGCCCGCTCAGCACGGGTGCGCGCGACAGCAGCCCGCGCTGGTCGCCGGACGG
CAAGACCCTCGCTTTTTTGCGCTCGGCGGAAAAAGACGGCAAATCCGAGCCGCCCCAGATTCATCTGTTGTCCCTGGACG
GGGGCGAAGCGCGGGCTTTGACCGACCTGCCCAAGGGGGCCGGGGGGATCTCCTGGTCCCCGGACAGCCGACGCATCGCC
TTTACTTCCTCCACCAAGAACGAAGACATTGCCGAGAAGCAGAAAAAAAACGAAGACGACAAGCCCAAAAAAAGCGATGT
GCGCGTCATCAAGCGGGCCATCTACCGCTTCAACGGCGCCGGCTACCTGGAGGAGGACCGGCCCGGACATATCTGGATAG
TCGACCTGCCCACCGACCCGGCGGCTCCGCCCCCGGCGGCAAAACAGATCACCAAAGGCGAATTCGAGGAAGATGCCCCT
GCCTGGTCGCCGGACGGCACGCGGCTGTATTTCACCTCCGACCGGACGCGCGAAGCTTACTATGAGCCTGTAGACACCGA
TATTTACACTGTCTCCGCAGGTGGCGGGGAGATCAGCCGGGTTGTCAACATCGACGGACCGATCGGCACCTTCGCCCTGA
GCCCCGACGGCCGACGGATCGCCTTTGTCGGGTTTGTCAATGCCAAACCCGAGTATTCCTACACCCAACCGGATCTGTTC
GTGGCCGATCTCAGTCCGGGAGCGGCTCCCAAAAATTTGACGGCGGATTATGACTTCGACGCCGGGGACGGCATCGGGGG
CGATCAGCGCGCCCCTCGGGCTGCTGCGGACTACCGGCCTGTCTGGAGCGGCGACGGCCGCTCGATTGTGATCGCGACCG
CCGAGCGGGGCCGTGCCAACCTCAAGCGCTTCGACGCCGCGGACGGCCGCGCGAGTGACGTTACCACCGGCGATCACGAA
ATCGCCGAGTACACCGCCACCCCCGACGGCAGCCGCTTTGCCGGGGTAATCTCCCGGCCCACCGAAGTGGGGGACATCTA
TCTGCTCTCTTTGGGCGCATCGCCGCGACGGCTTACCCGTGGAAATGCCCCGCTGTTCGACACGCTCCAGACCAGCGCGC
CGGAGGAGATTAACTATCCGAGCTTCGACGGCCAGACCATCCAGGGCTGGCTGTTCAAGCCGCCGGGATTCGAGGCGGGC
AAAAAATATCCGCTCATCCTCAACATTCACGGCGGTCCCCACATCGCCTGGGGGTACACGTTCTTCCACGAAGTCCAGTG
GATGGCCGCCAAGGGCTACGTGGTGCTCTACACCAACCCGCGCGGCTCCACCGGCTACGGCCAAAAGTTCGGCAACAGCA
TCCAGTTCAACTATCCCGGCGACGATGCCAAAGATCTGATGGCTGGGGTGGACTATCTGCTGGCGCGCGGCTATGTCGAT
GCGAACCGGTTGGGGGTGACCGGCGGCAGCGGCGGCGGGGTGCTCACCAACTGGCTGGTGGGACACACCGATCGCTTCAA
AGCGGCGGTATCCCAGCGCTCGATCGCCGACTGGACGAGCTGGTGGTACACCGCCGACTTCACCCTCTTTACGCCGACCT
GGTTTCGGGGAGCCCCCTGGCGGGAGGAGGCCGATTTCAAGGCCCGCTCGCCTATGACTTACGTCGAAAAGATCAAGACA
CCCCTGATGCTCATCGAAGGGGAGGCGGACCTGCGCACCCCGCCCGGGGCCGGCGGCGAACAACTGTTTCGGGCGCTCAA
ATACCTGAAGCGGCCGGTGGTGATGGTGCAATTTCCGGGCGAGAACCACGATCTGTCGCGCACGGGCAAGCCCTCGTACC
GCATCGAGCGGCTGCAGCACATCGTGGGCTGGTTCGACAAATATTTGCAGGGTGTCCCCAAACCCGAGTACGACTTGCCT
GCGGCCGGACCGGTGCGGCAGGAGGCCCCTTAG

Upstream 100 bases:

>100_bases
GCGATTTGCAGCGGGCGATGATTTTCGGTGCGGCCTGGAACCACGGGACAAATTTTACAGTCCGACTTCCTGATCCACAC
TCCACCGAAGGCGACTGCCC

Downstream 100 bases:

>100_bases
GACAGGTTTTAGTCAGCGCGCCTTGCCGCCTGGTACTCTCACTTCACCGGCGCCGGGGCCACTTCGTAAACATCTCGGTC
CGCGCCGAGGCGACCAGGTA

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MGLKCLCRRAVLAAALFVCCAGFAVPLPGIAAESKRPITEKDLLKFNWVADPRLSPDGARVVYVRVSVDEKKDTYTTSLW
QVATATGEARPLSTGARDSSPRWSPDGKTLAFLRSAEKDGKSEPPQIHLLSLDGGEARALTDLPKGAGGISWSPDSRRIA
FTSSTKNEDIAEKQKKNEDDKPKKSDVRVIKRAIYRFNGAGYLEEDRPGHIWIVDLPTDPAAPPPAAKQITKGEFEEDAP
AWSPDGTRLYFTSDRTREAYYEPVDTDIYTVSAGGGEISRVVNIDGPIGTFALSPDGRRIAFVGFVNAKPEYSYTQPDLF
VADLSPGAAPKNLTADYDFDAGDGIGGDQRAPRAAADYRPVWSGDGRSIVIATAERGRANLKRFDAADGRASDVTTGDHE
IAEYTATPDGSRFAGVISRPTEVGDIYLLSLGASPRRLTRGNAPLFDTLQTSAPEEINYPSFDGQTIQGWLFKPPGFEAG
KKYPLILNIHGGPHIAWGYTFFHEVQWMAAKGYVVLYTNPRGSTGYGQKFGNSIQFNYPGDDAKDLMAGVDYLLARGYVD
ANRLGVTGGSGGGVLTNWLVGHTDRFKAAVSQRSIADWTSWWYTADFTLFTPTWFRGAPWREEADFKARSPMTYVEKIKT
PLMLIEGEADLRTPPGAGGEQLFRALKYLKRPVVMVQFPGENHDLSRTGKPSYRIERLQHIVGWFDKYLQGVPKPEYDLP
AAGPVRQEAP

Sequences:

>Translated_730_residues
MGLKCLCRRAVLAAALFVCCAGFAVPLPGIAAESKRPITEKDLLKFNWVADPRLSPDGARVVYVRVSVDEKKDTYTTSLW
QVATATGEARPLSTGARDSSPRWSPDGKTLAFLRSAEKDGKSEPPQIHLLSLDGGEARALTDLPKGAGGISWSPDSRRIA
FTSSTKNEDIAEKQKKNEDDKPKKSDVRVIKRAIYRFNGAGYLEEDRPGHIWIVDLPTDPAAPPPAAKQITKGEFEEDAP
AWSPDGTRLYFTSDRTREAYYEPVDTDIYTVSAGGGEISRVVNIDGPIGTFALSPDGRRIAFVGFVNAKPEYSYTQPDLF
VADLSPGAAPKNLTADYDFDAGDGIGGDQRAPRAAADYRPVWSGDGRSIVIATAERGRANLKRFDAADGRASDVTTGDHE
IAEYTATPDGSRFAGVISRPTEVGDIYLLSLGASPRRLTRGNAPLFDTLQTSAPEEINYPSFDGQTIQGWLFKPPGFEAG
KKYPLILNIHGGPHIAWGYTFFHEVQWMAAKGYVVLYTNPRGSTGYGQKFGNSIQFNYPGDDAKDLMAGVDYLLARGYVD
ANRLGVTGGSGGGVLTNWLVGHTDRFKAAVSQRSIADWTSWWYTADFTLFTPTWFRGAPWREEADFKARSPMTYVEKIKT
PLMLIEGEADLRTPPGAGGEQLFRALKYLKRPVVMVQFPGENHDLSRTGKPSYRIERLQHIVGWFDKYLQGVPKPEYDLP
AAGPVRQEAP
>Mature_729_residues
GLKCLCRRAVLAAALFVCCAGFAVPLPGIAAESKRPITEKDLLKFNWVADPRLSPDGARVVYVRVSVDEKKDTYTTSLWQ
VATATGEARPLSTGARDSSPRWSPDGKTLAFLRSAEKDGKSEPPQIHLLSLDGGEARALTDLPKGAGGISWSPDSRRIAF
TSSTKNEDIAEKQKKNEDDKPKKSDVRVIKRAIYRFNGAGYLEEDRPGHIWIVDLPTDPAAPPPAAKQITKGEFEEDAPA
WSPDGTRLYFTSDRTREAYYEPVDTDIYTVSAGGGEISRVVNIDGPIGTFALSPDGRRIAFVGFVNAKPEYSYTQPDLFV
ADLSPGAAPKNLTADYDFDAGDGIGGDQRAPRAAADYRPVWSGDGRSIVIATAERGRANLKRFDAADGRASDVTTGDHEI
AEYTATPDGSRFAGVISRPTEVGDIYLLSLGASPRRLTRGNAPLFDTLQTSAPEEINYPSFDGQTIQGWLFKPPGFEAGK
KYPLILNIHGGPHIAWGYTFFHEVQWMAAKGYVVLYTNPRGSTGYGQKFGNSIQFNYPGDDAKDLMAGVDYLLARGYVDA
NRLGVTGGSGGGVLTNWLVGHTDRFKAAVSQRSIADWTSWWYTADFTLFTPTWFRGAPWREEADFKARSPMTYVEKIKTP
LMLIEGEADLRTPPGAGGEQLFRALKYLKRPVVMVQFPGENHDLSRTGKPSYRIERLQHIVGWFDKYLQGVPKPEYDLPA
AGPVRQEAP

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=483, Percent_Identity=24.6376811594203, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI37577089, Length=242, Percent_Identity=28.5123966942149, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI18450280, Length=242, Percent_Identity=28.5123966942149, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI194394146, Length=245, Percent_Identity=23.6734693877551, Blast_Score=70, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25149159, Length=263, Percent_Identity=30.0380228136882, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17552908, Length=283, Percent_Identity=26.1484098939929, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17508017, Length=293, Percent_Identity=26.2798634812287, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508019, Length=293, Percent_Identity=26.2798634812287, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45551969, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550825, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45553511, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 80041; Mature: 79910

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKCLCRRAVLAAALFVCCAGFAVPLPGIAAESKRPITEKDLLKFNWVADPRLSPDGAR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCEEEEEEECCCCCCCCCE
VVYVRVSVDEKKDTYTTSLWQVATATGEARPLSTGARDSSPRWSPDGKTLAFLRSAEKDG
EEEEEEEECCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCC
KSEPPQIHLLSLDGGEARALTDLPKGAGGISWSPDSRRIAFTSSTKNEDIAEKQKKNEDD
CCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCC
KPKKSDVRVIKRAIYRFNGAGYLEEDRPGHIWIVDLPTDPAAPPPAAKQITKGEFEEDAP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCC
AWSPDGTRLYFTSDRTREAYYEPVDTDIYTVSAGGGEISRVVNIDGPIGTFALSPDGRRI
CCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEECCCCCEE
AFVGFVNAKPEYSYTQPDLFVADLSPGAAPKNLTADYDFDAGDGIGGDQRAPRAAADYRP
EEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VWSGDGRSIVIATAERGRANLKRFDAADGRASDVTTGDHEIAEYTATPDGSRFAGVISRP
CCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHEEECCCCCCEEEHEECCC
TEVGDIYLLSLGASPRRLTRGNAPLFDTLQTSAPEEINYPSFDGQTIQGWLFKPPGFEAG
CCCCEEEEEEECCCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
KKYPLILNIHGGPHIAWGYTFFHEVQWMAAKGYVVLYTNPRGSTGYGQKFGNSIQFNYPG
CCCCEEEEECCCCEEEEHHHHHHHHEEEEECCEEEEEECCCCCCCCHHHCCCEEEEECCC
DDAKDLMAGVDYLLARGYVDANRLGVTGGSGGGVLTNWLVGHTDRFKAAVSQRSIADWTS
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHC
WWYTADFTLFTPTWFRGAPWREEADFKARSPMTYVEKIKTPLMLIEGEADLRTPPGAGGE
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCHH
QLFRALKYLKRPVVMVQFPGENHDLSRTGKPSYRIERLQHIVGWFDKYLQGVPKPEYDLP
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AAGPVRQEAP
CCCCCCCCCC
>Mature Secondary Structure 
GLKCLCRRAVLAAALFVCCAGFAVPLPGIAAESKRPITEKDLLKFNWVADPRLSPDGAR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCEEEEEEECCCCCCCCCE
VVYVRVSVDEKKDTYTTSLWQVATATGEARPLSTGARDSSPRWSPDGKTLAFLRSAEKDG
EEEEEEEECCCCCCHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHCC
KSEPPQIHLLSLDGGEARALTDLPKGAGGISWSPDSRRIAFTSSTKNEDIAEKQKKNEDD
CCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCC
KPKKSDVRVIKRAIYRFNGAGYLEEDRPGHIWIVDLPTDPAAPPPAAKQITKGEFEEDAP
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCC
AWSPDGTRLYFTSDRTREAYYEPVDTDIYTVSAGGGEISRVVNIDGPIGTFALSPDGRRI
CCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCCCCEEEEEECCCCCEEEEECCCCCEE
AFVGFVNAKPEYSYTQPDLFVADLSPGAAPKNLTADYDFDAGDGIGGDQRAPRAAADYRP
EEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VWSGDGRSIVIATAERGRANLKRFDAADGRASDVTTGDHEIAEYTATPDGSRFAGVISRP
CCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHEEECCCCCCEEEHEECCC
TEVGDIYLLSLGASPRRLTRGNAPLFDTLQTSAPEEINYPSFDGQTIQGWLFKPPGFEAG
CCCCEEEEEEECCCCCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
KKYPLILNIHGGPHIAWGYTFFHEVQWMAAKGYVVLYTNPRGSTGYGQKFGNSIQFNYPG
CCCCEEEEECCCCEEEEHHHHHHHHEEEEECCEEEEEECCCCCCCCHHHCCCEEEEECCC
DDAKDLMAGVDYLLARGYVDANRLGVTGGSGGGVLTNWLVGHTDRFKAAVSQRSIADWTS
CCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHC
WWYTADFTLFTPTWFRGAPWREEADFKARSPMTYVEKIKTPLMLIEGEADLRTPPGAGGE
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCHH
QLFRALKYLKRPVVMVQFPGENHDLSRTGKPSYRIERLQHIVGWFDKYLQGVPKPEYDLP
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
AAGPVRQEAP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]