Click here to switch to the map view.

The map label for this gene is bvgS [H]

Identifier: 34498464

GI number: 34498464

Start: 3284381

End: 3286096

Strand: Reverse

Name: bvgS [H]

Synonym: CV_3009

Alternate gene names: 34498464

Gene position: 3286096-3284381 (Counterclockwise)

Preceding gene: 34498465

Following gene: 34498455

Centisome position: 69.17

GC content: 68.82

Gene sequence:

>1716_bases
ATGAAGCGCTATGTGCAGGCGCCGTGGTGGCTGATCCTGTCGCTGCTGGTGCTGCTGCTGGCCGCCGGCTGGAATTTCTA
CCGGATAGACCGCGCCAGCCAGGCCCTGATAGACAGCGGCAAGAGCGAGCAGCTGTACTGGACGGTGGCGCAGCTGCACA
TCGAGCTGGAGAAGACCCGGGCGGAGCTGATCGGCTACGCGGCCGAGCCCTCGTCGTTCGATCCGGGCGCGCAGTTCCAG
TTGCTGCAAAGCCGCTACCAGGTGTTCGAGGCGCCGGACAGCGTGCTGGTGCACCGCCAACTGCGCCGGGTGGCCGGCTT
CGAGGCGCTGGTCGGCGCGCTGGGGCCGCTGATCCATGACAAGAGCTGGCTGCGGATCACGCCCGACTGGGCGCGCCGCA
TGGTGGTGCGCATGGACGCGCTGCGCCCGGTGCTGGCCAATTTCGCGGTGCAGAGCCGCGAAGCCGAGGTGTCTACCCGC
GTGGCGCGCACCAGGGCGCTGGCCAGCCAGCGCTCGCAGATGCTGATGCTGCAGCTGGTGCTGTGCGGCGGCATCTGCGG
CGTGCTGCTGGTGTTGATGCGCTTCCGCGAAGTGAAGGAGCTGGCCGAGGTCAGGCAGTCGCTGCTCGAGCAGGAGCGCG
CGGCGCACCAGGCCACCGTCGCGCTGGAGCTGGACCGAACCACCTTTCTGGGCACGCTGGGCCACGAGATCCGCTCCCCG
CTGCAATCGATGCAGATGTGCATGGAGCTGGTGGAGCCCGCGGTGATGCCGCAGCCGGCCGCCCAGTTGGCGCTCAAGCG
GATGAAGGCCGGCATGGCGCAGCTGACCAGCCAGGTCCACGACATCATGGACATCTCGGCGATCAAGAACATGCAGCTGC
GGCTGAATCCGGGCCGGGTCAAGCCGTCCGCGGCGCTGAAAGCGGTGATCGACGTGATGCAGCCGCTGGCGGACGCCAAG
GGCCTGACCCTGCGCTACGAAGAGGATGGCCTGCCCGAGCGCGCGCTGCTGGACGAGACCCGCTTGCGCCAGATCGTCGG
CAATCTGGTGTCCAACGCGATACGCTACACCGATCAGGGCGGCGTCACGCTGAAGGCGCGAGGCGTCAGCGACGCCGATC
ATTCCGAACTGTGGCTGGAGGTCAGCGACACCGGCATCGGCATCGCCGACGAGGACAGGCAGAGGATATTCCAGCCGTTC
AGCCAGGGGCGCAATCGCCGTCCCGGCAGCAGCGGCCTGGGCCTGTCCATCGTCAAGGAGCTGGTGCGCCTGTTCGGCGG
CAGCATAGAAATGGAAAGCGCGGTGGGCGCGGGTTCCGTGTTCACCGTCAGGCTGCCGCTGCGCGCGGTGGGAGAGAGCG
AGCAGGGGCGCAGCGTGCTGGTGGTCGAGGACGACGACGAGATCCGCGGCTCGATCGCCGAACTGCTGGGCCAGGAGGGC
TACCAGGTATCCTGCGCGGCGACGCTGTCGCAAGCGGCCGGCAGCCTGGTGCAACAGCGTTTCGACGTGTTGCTGCTGGA
CATGCAGCTGGGCGGCGACAGCGGCTACCAGCTGGCGGAGCTGGCGCGCAAGCAGCCGCAGCGGCCGCTGATGCTGGCGA
TGAGCGCCGACCCCGACGAATTCGCCGACGCGCGCGCAGGCTGGTTCGCCGCCAGGCTGCGCAAGCCTTTCGACAGCGGC
CAGCTGCGCGCCGCGCTGGCGGCGCTGCCGCTGTAG

Upstream 100 bases:

>100_bases
ATCCATTGCAGACCATGCCGGACGCCGACAAGGGCCCGCCGCTGGACGCCAAGCTGGTATGGCAGGTCGAGGCGATGGAG
GTGATGTGAGGCTGGGCGGC

Downstream 100 bases:

>100_bases
CGCAAAGGCGGCAGGGCAAAAAAACAGGCTCCGTGCGGAGCCTGTTTTGTTATCGGCTTGAGCGAGGCTCAGGCATGTTC
CAGCGCGTTGGTGACCATGT

Product: sensor/response regulator hybrid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MKRYVQAPWWLILSLLVLLLAAGWNFYRIDRASQALIDSGKSEQLYWTVAQLHIELEKTRAELIGYAAEPSSFDPGAQFQ
LLQSRYQVFEAPDSVLVHRQLRRVAGFEALVGALGPLIHDKSWLRITPDWARRMVVRMDALRPVLANFAVQSREAEVSTR
VARTRALASQRSQMLMLQLVLCGGICGVLLVLMRFREVKELAEVRQSLLEQERAAHQATVALELDRTTFLGTLGHEIRSP
LQSMQMCMELVEPAVMPQPAAQLALKRMKAGMAQLTSQVHDIMDISAIKNMQLRLNPGRVKPSAALKAVIDVMQPLADAK
GLTLRYEEDGLPERALLDETRLRQIVGNLVSNAIRYTDQGGVTLKARGVSDADHSELWLEVSDTGIGIADEDRQRIFQPF
SQGRNRRPGSSGLGLSIVKELVRLFGGSIEMESAVGAGSVFTVRLPLRAVGESEQGRSVLVVEDDDEIRGSIAELLGQEG
YQVSCAATLSQAAGSLVQQRFDVLLLDMQLGGDSGYQLAELARKQPQRPLMLAMSADPDEFADARAGWFAARLRKPFDSG
QLRAALAALPL

Sequences:

>Translated_571_residues
MKRYVQAPWWLILSLLVLLLAAGWNFYRIDRASQALIDSGKSEQLYWTVAQLHIELEKTRAELIGYAAEPSSFDPGAQFQ
LLQSRYQVFEAPDSVLVHRQLRRVAGFEALVGALGPLIHDKSWLRITPDWARRMVVRMDALRPVLANFAVQSREAEVSTR
VARTRALASQRSQMLMLQLVLCGGICGVLLVLMRFREVKELAEVRQSLLEQERAAHQATVALELDRTTFLGTLGHEIRSP
LQSMQMCMELVEPAVMPQPAAQLALKRMKAGMAQLTSQVHDIMDISAIKNMQLRLNPGRVKPSAALKAVIDVMQPLADAK
GLTLRYEEDGLPERALLDETRLRQIVGNLVSNAIRYTDQGGVTLKARGVSDADHSELWLEVSDTGIGIADEDRQRIFQPF
SQGRNRRPGSSGLGLSIVKELVRLFGGSIEMESAVGAGSVFTVRLPLRAVGESEQGRSVLVVEDDDEIRGSIAELLGQEG
YQVSCAATLSQAAGSLVQQRFDVLLLDMQLGGDSGYQLAELARKQPQRPLMLAMSADPDEFADARAGWFAARLRKPFDSG
QLRAALAALPL
>Mature_571_residues
MKRYVQAPWWLILSLLVLLLAAGWNFYRIDRASQALIDSGKSEQLYWTVAQLHIELEKTRAELIGYAAEPSSFDPGAQFQ
LLQSRYQVFEAPDSVLVHRQLRRVAGFEALVGALGPLIHDKSWLRITPDWARRMVVRMDALRPVLANFAVQSREAEVSTR
VARTRALASQRSQMLMLQLVLCGGICGVLLVLMRFREVKELAEVRQSLLEQERAAHQATVALELDRTTFLGTLGHEIRSP
LQSMQMCMELVEPAVMPQPAAQLALKRMKAGMAQLTSQVHDIMDISAIKNMQLRLNPGRVKPSAALKAVIDVMQPLADAK
GLTLRYEEDGLPERALLDETRLRQIVGNLVSNAIRYTDQGGVTLKARGVSDADHSELWLEVSDTGIGIADEDRQRIFQPF
SQGRNRRPGSSGLGLSIVKELVRLFGGSIEMESAVGAGSVFTVRLPLRAVGESEQGRSVLVVEDDDEIRGSIAELLGQEG
YQVSCAATLSQAAGSLVQQRFDVLLLDMQLGGDSGYQLAELARKQPQRPLMLAMSADPDEFADARAGWFAARLRKPFDSG
QLRAALAALPL

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=33.7254901960784, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788713, Length=358, Percent_Identity=26.8156424581006, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI48994928, Length=344, Percent_Identity=29.3604651162791, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI87081816, Length=359, Percent_Identity=31.4763231197772, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789149, Length=330, Percent_Identity=27.8787878787879, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=282, Percent_Identity=28.3687943262411, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.1304347826087, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=27.6150627615063, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=281, Percent_Identity=29.1814946619217, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=263, Percent_Identity=26.2357414448669, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=27.1111111111111, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=25.2173913043478, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=240, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=79, Percent_Identity=43.0379746835443, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63067; Mature: 63067

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYVQAPWWLILSLLVLLLAAGWNFYRIDRASQALIDSGKSEQLYWTVAQLHIELEKTR
CCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
AELIGYAAEPSSFDPGAQFQLLQSRYQVFEAPDSVLVHRQLRRVAGFEALVGALGPLIHD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSWLRITPDWARRMVVRMDALRPVLANFAVQSREAEVSTRVARTRALASQRSQMLMLQLV
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGGICGVLLVLMRFREVKELAEVRQSLLEQERAAHQATVALELDRTTFLGTLGHEIRSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHH
LQSMQMCMELVEPAVMPQPAAQLALKRMKAGMAQLTSQVHDIMDISAIKNMQLRLNPGRV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
KPSAALKAVIDVMQPLADAKGLTLRYEEDGLPERALLDETRLRQIVGNLVSNAIRYTDQG
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVTLKARGVSDADHSELWLEVSDTGIGIADEDRQRIFQPFSQGRNRRPGSSGLGLSIVKE
CEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LVRLFGGSIEMESAVGAGSVFTVRLPLRAVGESEQGRSVLVVEDDDEIRGSIAELLGQEG
HHHHHCCCEEEHHCCCCCCEEEEEECHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCC
YQVSCAATLSQAAGSLVQQRFDVLLLDMQLGGDSGYQLAELARKQPQRPLMLAMSADPDE
CEEHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHH
FADARAGWFAARLRKPFDSGQLRAALAALPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKRYVQAPWWLILSLLVLLLAAGWNFYRIDRASQALIDSGKSEQLYWTVAQLHIELEKTR
CCCCCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCEEEHHHHHHHHHHHH
AELIGYAAEPSSFDPGAQFQLLQSRYQVFEAPDSVLVHRQLRRVAGFEALVGALGPLIHD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KSWLRITPDWARRMVVRMDALRPVLANFAVQSREAEVSTRVARTRALASQRSQMLMLQLV
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGGICGVLLVLMRFREVKELAEVRQSLLEQERAAHQATVALELDRTTFLGTLGHEIRSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHH
LQSMQMCMELVEPAVMPQPAAQLALKRMKAGMAQLTSQVHDIMDISAIKNMQLRLNPGRV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
KPSAALKAVIDVMQPLADAKGLTLRYEEDGLPERALLDETRLRQIVGNLVSNAIRYTDQG
CHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVTLKARGVSDADHSELWLEVSDTGIGIADEDRQRIFQPFSQGRNRRPGSSGLGLSIVKE
CEEEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LVRLFGGSIEMESAVGAGSVFTVRLPLRAVGESEQGRSVLVVEDDDEIRGSIAELLGQEG
HHHHHCCCEEEHHCCCCCCEEEEEECHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCC
YQVSCAATLSQAAGSLVQQRFDVLLLDMQLGGDSGYQLAELARKQPQRPLMLAMSADPDE
CEEHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHH
FADARAGWFAARLRKPFDSGQLRAALAALPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]