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The map label for this gene is invA [H]

Identifier: 34498085

GI number: 34498085

Start: 2836202

End: 2838262

Strand: Reverse

Name: invA [H]

Synonym: CV_2630

Alternate gene names: 34498085

Gene position: 2838262-2836202 (Counterclockwise)

Preceding gene: 34498086

Following gene: 34498084

Centisome position: 59.74

GC content: 66.42

Gene sequence:

>2061_bases
CTGAACTCCCTGCTGAACGGCGCGCGATCGCGCCCGGAACTGCTGATCCTGCTGTTGATGGTGATGATCATCGCGATGCT
GATCATCCCGCTGCCCACCTACCTGGTGGACTTCCTGATCGGCCTGAACATCGTGCTGGCGGTGCTGGTGTTCATGGGCT
CGTTCTACATCGACCGCATCCTCAGCTTTTCCACCTTCCCGTCGGTGTTGCTGATCACCACGCTGTTCCGCCTGGCGCTG
TCCATCAGCACCAGCCGGCTGATCCTGATCGAGGCCGACGCCGGCGAGATCATCGCCACCTTCGGCCAGTTCGTGATCGG
CGACAGCCTGGCGGTGGGCTTCGTGGTGTTCTCCATCGTCACCGTGGTCCAGTTCATCGTGATCACCAAGGGGTCGGAGC
GGGTGGCCGAAGTGGCGGCGCGCTTCTCGCTGGACGGCATGCCCGGCAAGCAGATGAGCATCGACGCCGACCTCAAGGCC
GGCATCATCGACGCCGACGGCGCGCGCGAGCGCCGCAGCGTGCTGGAGCGCGAGAGCCAGCTGTACGGCTCCTTCGACGG
CGCGATGAAGTTCATCAAGGGCGACGCCATCGCCGGCATCATCATCATTTTCGTCAACTTCATCGGCGGCATCGCGGTGG
GCATGACCCAGCACGGCATGGACCTGTCCGCCGCCTTGTCCACCTACACGATGCTCACCATCGGCGACGGCCTGGTCGCG
CAGATCCCGGCGCTGCTGATCGCCATCAGCGCCGGCTTCATCGTCACCCGCGTCAACGGCGACAGCGACAACATGGGCCG
CAACATCATGAGCCAGCTGCTGGGCAATCCCTTCGTGCTGGTGGTGACCGCGGTGCTGGCGCTGGCGGTGGGCATGCTGC
CGGGCTTCCCGCTGATCGTGTTCCTGATCCTGGCCGCCGCGCTGGGCGGCCTGTTCTATTACAAGCGACGCGCCGCCGCC
GGCAAGCCCGCGCCGGGCATGCCGGCCCAGGCGGCCAAGGGCGGTTCGGCTCCGGGCGACGCGGCGAGGACGGGCGGGGC
GGACAGTTCGCTCGGCCTGATAGGCAATCTGGACAAGGTGGCGGCGGAAACCGTGCCGCTGATCTTGCTGGTGCCGGCCA
GCCGGCGCGCGGCGCTGGAGCAGGCGCAGCTGGCCGAGCGCCTGCGCAGCCAGTTTTTCATCGACTACGGCGTGCGGCTG
CCGGACATGCTGCTGCGCGAAGCCGAGGGCATGGACGACAACCGGGTGGCGGTGCTGATCAACGAGATCCGCGCCGATGA
ATTCCCGATCCGCTTCGACCTCGCGCGCGTGGTCAATCCCAGCGAGGAAATCCTGGCGCTGGACGTGCAGCCGGTGCTGG
AGCGCGAGTGCGTGTGGGTGAGGCCGGAGGACGGCGACCGGCTGGCCAAGCTGGGCTACCAGCTGCGCCCGGCGCTGGAC
GAGCTCTACCACTGCCTGGCGGCGCTGCTGGCCCGCCACGTCAACGAGTATTTCGGCGTCCAGGAAACCAAGCACATGCT
GGACCAGCTGGAGGGCAAGTACCCCGACCTGCTGAAGGAGGTGCTGCGCCATGCCACCGTGCAGCGCATCGCCGAAGTGC
TGCAGCGCCTGCTGGCGGAACGCATCTCGGTGCGCAACATGAAGCTGATCATGGAGGCGCTGGCGCTGTGGGCGCCGCGC
GAGAAAGACGTGATCAACCTGGTCGAACACGTCCGCGGCGCGCTGGCCCGCTACATCTGCCACAAATTCTCGGCCGGCGG
CGAGCTGCGGGCGGTGATGGTGTCGGCAGAAGTGGAGGACATGGTGCGCAAGGGCGTGCGCCAGACCTCGGCCGGCGCCT
TCCTCAACCTGGAGCCGGCGGCGTCCGACGAGCTGATGGACCTGTTCGCGCTGGGCCTGGAGGGCCTGGGCGTCGCCTAC
AAGGACATGGTGCTGCTCGCCTCGGTCGACGTGCGGCGCTTCATCAAGAAATTGGTCGAAACCCGCTTCCGCGAGCTGGA
AGTGGTGTCTTTCGGCGAAATCACCGACAGCGTGTCGGTCAATGTGATCAAAACTATCTGA

Upstream 100 bases:

>100_bases
TACCGGCATGAACAGATAGAGCGGCGGCGCGAAAACTGACGCTGTTTGACGAACAACCCGGCGCATGGGCGCCTGTTTGC
GATTGGATGGACTTCTGGTG

Downstream 100 bases:

>100_bases
CGAGGACGCAAGCCCATGTTCAAACAGGATATCGCCCAACTGGTCCGTTCAGCGCTGCAGGAAAGCGGCTGCGACCCCAG
CCTGCTGGGCCCGCTGGACA

Product: invasion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRILSFSTFPSVLLITTLFRLAL
SISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKA
GIIDADGARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIVFLILAAALGGLFYYKRRAAA
GKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKVAAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRL
PDMLLREAEGMDDNRVAVLINEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAERISVRNMKLIMEALALWAPR
EKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVEDMVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAY
KDMVLLASVDVRRFIKKLVETRFRELEVVSFGEITDSVSVNVIKTI

Sequences:

>Translated_686_residues
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRILSFSTFPSVLLITTLFRLAL
SISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKA
GIIDADGARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIVFLILAAALGGLFYYKRRAAA
GKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKVAAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRL
PDMLLREAEGMDDNRVAVLINEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAERISVRNMKLIMEALALWAPR
EKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVEDMVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAY
KDMVLLASVDVRRFIKKLVETRFRELEVVSFGEITDSVSVNVIKTI
>Mature_686_residues
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRILSFSTFPSVLLITTLFRLAL
SISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKA
GIIDADGARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIVFLILAAALGGLFYYKRRAAA
GKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKVAAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRL
PDMLLREAEGMDDNRVAVLINEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAERISVRNMKLIMEALALWAPR
EKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVEDMVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAY
KDMVLLASVDVRRFIKKLVETRFRELEVVSFGEITDSVSVNVIKTI

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the invE protein [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=686, Percent_Identity=34.6938775510204, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74609; Mature: 74609

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRI
CCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFSTFPSVLLITTLFRLALSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKAGIIDADGARERRSVLERESQ
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEECCCCCHHHHHHHHHHHH
LYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHH
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIV
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
FLILAAALGGLFYYKRRAAAGKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHH
AAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRLPDMLLREAEGMDDNRVAVLI
HHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEE
NEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
HHHCCCCCCHHHHHHHHCCCCHHEEEECCCHHHCCCEEEECCCCCCHHHHHCHHHHHHHH
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAE
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RISVRNMKLIMEALALWAPREKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVED
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
MVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAYKDMVLLASVDVRRFIKKLVE
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TRFRELEVVSFGEITDSVSVNVIKTI
HHHHHHHEEECCCCCCCCCEEEEECC
>Mature Secondary Structure
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRI
CCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFSTFPSVLLITTLFRLALSISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHH
TVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKAGIIDADGARERRSVLERESQ
HHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCEECCCCCHHHHHHHHHHHH
LYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
HHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHH
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIV
HHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
FLILAAALGGLFYYKRRAAAGKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHH
AAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRLPDMLLREAEGMDDNRVAVLI
HHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEE
NEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
HHHCCCCCCHHHHHHHHCCCCHHEEEECCCHHHCCCEEEECCCCCCHHHHHCHHHHHHHH
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAE
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RISVRNMKLIMEALALWAPREKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVED
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHH
MVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAYKDMVLLASVDVRRFIKKLVE
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TRFRELEVVSFGEITDSVSVNVIKTI
HHHHHHHEEECCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]