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The map label for this gene is cheB1

Identifier: 34497961

GI number: 34497961

Start: 2698292

End: 2699371

Strand: Reverse

Name: cheB1

Synonym: CV_2506

Alternate gene names: 34497961

Gene position: 2699371-2698292 (Counterclockwise)

Preceding gene: 34497962

Following gene: 34497960

Centisome position: 56.82

GC content: 68.06

Gene sequence:

>1080_bases
ATGAGCGTTTCCGTGCTGATCGTCGACGATTCCGCGGTGGTGCGCGAGGTGCTGTCCCAGATGTTGTCTTCCGCGCCGGA
CATCGAAGTGCTGGGCGCCGCGCCCGACCCGATATTCGCGATGACCCGGATGAAGCAGCGCTGGCCGGACGTGATCGTGC
TGGATATCGAGATGCCGCGGATGGATGGCCTCACCTTCCTGCGCAAGATCATGGACGAGCGGCCGACGCCGGTGATCATC
TGCTCGTCGCTGACCGAGAAAGGTGCCCGCATCACGCTGGATGCGTTGGCCGCCGGCGCGGTGGCGATCATCACCAAGCC
GGCGCTCAACCAGCGGGCCTTCCTGCTGGAGGCGGCAAAGGAGCTGGTGCAGGAGGTGCGCGACGCGGCCAGGGCCAAGA
TGGGCGTGGTCAAGCGCATTTCGCAAGGCGCGGCGGAGCACGCGCCGCCGGCGCCCAAGCTGACCGCCGACGTGGTGCTG
GAAGCGCCGTCCGGCCTGGAAAAATACCGGACCACCGAGAAGATCATCGCCATCGGCACGTCCACCGGCGGCACCCAGGC
GCTGGAGTACCTGCTGCCCAAGCTGCCCGCCACCTGTCCCGGGGTGGCGGTGGTGCAGCACATGCCGGAGAAATTCACCG
CGTCCTTCGCCGAGCGGCTGAACCGGCTGTGCCGGGTGGAGGTGAAGGAGGCGCAGACCGGCGACCGGCTGATTTCCGGC
GTGGCGCTGATCGCCCCGGGCGGCAAACATCTGCTGGTGAAGCGCAATGGTGCGCAGTACGTGGCCGACGTGAAGGACGG
GCCGCTGGTGTCGCGCCATAGGCCGTCGGTGGACGTGCTGTTCCGCTCGGTGGCGGTGTGCGCGGGCGGCAACGCGATAG
GCGTGATCATGACCGGAATGGGGGACGACGGCGCGCGCGGCATGCGCGAGATGCATGACGCCGGCGCCCGCACCGTCGCC
CAGGACGAAGAGTCCTGCGTGGTGTTCGGCATGCCGGCCGAGGCGATCAATCATGGCGGCGTGGACGAGGTGATGTCGCT
GGAGCGCATCGCCCACATGCTGGCAGGCATCAGGGGCTGA

Upstream 100 bases:

>100_bases
GCCATTCCGAATCCCTGCACAAGCTGGATCTGCCGCTGGCGCAGGAAGAACCGTCGCGCTACCGGTTCGAGGCTTCGCGT
CTGAAAAGTGGAGGAGCAAG

Downstream 100 bases:

>100_bases
TCATGGGGTATCTGGACAAGTGGAAAGATCGGTCCGTGATGGTGGTGGACGACTCCGCCACCCACAGGCTGCTGGCGGTG
GGTTTGCTGGAGGAAATCGG

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPRMDGLTFLRKIMDERPTPVII
CSSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAKELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVL
EAPSGLEKYRTTEKIIAIGTSTGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISG
VALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGMGDDGARGMREMHDAGARTVA
QDEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG

Sequences:

>Translated_359_residues
MSVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPRMDGLTFLRKIMDERPTPVII
CSSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAKELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVL
EAPSGLEKYRTTEKIIAIGTSTGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISG
VALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGMGDDGARGMREMHDAGARTVA
QDEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG
>Mature_358_residues
SVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPRMDGLTFLRKIMDERPTPVIIC
SSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAKELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVLE
APSGLEKYRTTEKIIAIGTSTGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISGV
ALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGMGDDGARGMREMHDAGARTVAQ
DEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=356, Percent_Identity=50.2808988764045, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB1_CHRVO (Q7NV40)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902176.1
- ProteinModelPortal:   Q7NV40
- SMR:   Q7NV40
- GeneID:   2548385
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2506
- NMPDR:   fig|243365.1.peg.2506
- HOGENOM:   HBG705324
- OMA:   EIMATAS
- PhylomeDB:   Q7NV40
- ProtClustDB:   PRK12555
- BioCyc:   CVIO243365:CV_2506-MONOMER
- BRENDA:   3.1.1.61
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 38253; Mature: 38122

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 181-181 ACT_SITE 207-207 ACT_SITE 303-303

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPR
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
MDGLTFLRKIMDERPTPVIICSSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAK
CCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEHHHHHCCEEEEEECCCCCHHHHHHHHHH
ELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVLEAPSGLEKYRTTEKIIAIGT
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHEEEECCCCHHHHHCCCEEEEEEC
STGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISG
CCCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHC
VALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGM
EEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECC
GDDGARGMREMHDAGARTVAQDEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG
CCCHHHHHHHHHHHCCCHHCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVSVLIVDDSAVVREVLSQMLSSAPDIEVLGAAPDPIFAMTRMKQRWPDVIVLDIEMPR
CEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCC
MDGLTFLRKIMDERPTPVIICSSLTEKGARITLDALAAGAVAIITKPALNQRAFLLEAAK
CCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEHHHHHCCEEEEEECCCCCHHHHHHHHHH
ELVQEVRDAARAKMGVVKRISQGAAEHAPPAPKLTADVVLEAPSGLEKYRTTEKIIAIGT
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHEEEECCCCHHHHHCCCEEEEEEC
STGGTQALEYLLPKLPATCPGVAVVQHMPEKFTASFAERLNRLCRVEVKEAQTGDRLISG
CCCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHC
VALIAPGGKHLLVKRNGAQYVADVKDGPLVSRHRPSVDVLFRSVAVCAGGNAIGVIMTGM
EEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECC
GDDGARGMREMHDAGARTVAQDEESCVVFGMPAEAINHGGVDEVMSLERIAHMLAGIRG
CCCHHHHHHHHHHHCCCHHCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782