BacMap

Definition	Chromobacterium violaceum ATCC 12472 chromosome, complete genome.
Accession	NC_005085
Length	4,751,080

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The map label for this gene is caiD [C]

Identifier: 34497940

GI number: 34497940

Start: 2675043

End: 2675858

Strand: Reverse

Name: caiD [C]

Synonym: CV_2485

Alternate gene names: 34497940

Gene position: 2675858-2675043 (Counterclockwise)

Preceding gene: 34497941

Following gene: 34497931

Centisome position: 56.32

GC content: 66.91

Gene sequence:

>816_bases
ATGATCAATTTGCAGACTGTGGCAGTGGAGCTGGACGAGAAAGTCGCCGTGCTGCGCTTCAATCGCGCCGACAAGGCCAA
TGCGCTGAACCTGCAGATGTGGCAAGACCTGCGCGCTGCGCTGGACTGGGCCGACGCCGAACCGGGCGTCCGCGCCGTGG
TGCTGGCAGGGCACGGCAAACATTTCTGCGCCGGCATCGACCTGGCGATGCTGGTGGGCTTGCAGTCCAGCATTCAGGAC
GAGTGCGAGGGCCGCAAGCGCGACAAGCTGCGCCGCGTGATCCTGGATCTGCAGGATTGCGTGAACAGCCTGGAGCGTTG
CCGCAAGCCGGTGATCGCCGCGATCCACGGCGCCTGTCTGGGCGGCGGCTTGGACATCGCGCTGGCGGCGGACTTCCGCT
TCGCCGCCGAGAACGCGGTTTTCGGCGTGCGCGAGGTGGACCTGGGCATGGTGGCCGACGTCGGCTCTCTGCAGCGCCTG
CCGAGGGTCGTGGGCGAAGGCGTGGCCCGCGAACTGGCGCTGACCGGCCGCGACATGGTGGCCGAGGAGGCGCTGGAGGT
CGGCCTGGTCAATCGGGTGGCGGAGGACGCCGATGCCGTGCTGGCGGCAGCCATGCAAAGCGCGAAGCTGATCGCCGGAA
AATCGCCGCTGGCGGTGCGCGGCAGCAAGGAAGTGATGAACTACAGCCGCGATCACAGCGTGGCAGACGGCCTGCAGTTC
GTCGCCGGCTGGAACGCGGCGATGCTGATCTCGGAGGACATCCAGAAGGCTGGCATGGCTGCGATGATGAAGCAGCAGGT
CAGCTTTCGGGACTGA

Upstream 100 bases:

>100_bases
TGGTCGAGGTGCTGGTCACCGACGAGTCCGGCGAGTCCCCCATCGTCTGCGAGATGCTGTGGGCCTGGGTTCCCAAGAAA
CGCCCGGAGGCGAAGACCGC

Downstream 100 bases:

>100_bases
GCTCCTGTCCGGCTGGACGCCTGTCCAGCCGGGATCATCCCCTCGTCGCGGCGCCAGTCCCGTTTTGGCCGGCGGGTATC
AAGAGCCTTGCCGGTCGCAG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MINLQTVAVELDEKVAVLRFNRADKANALNLQMWQDLRAALDWADAEPGVRAVVLAGHGKHFCAGIDLAMLVGLQSSIQD
ECEGRKRDKLRRVILDLQDCVNSLERCRKPVIAAIHGACLGGGLDIALAADFRFAAENAVFGVREVDLGMVADVGSLQRL
PRVVGEGVARELALTGRDMVAEEALEVGLVNRVAEDADAVLAAAMQSAKLIAGKSPLAVRGSKEVMNYSRDHSVADGLQF
VAGWNAAMLISEDIQKAGMAAMMKQQVSFRD

Sequences:

>Translated_271_residues
MINLQTVAVELDEKVAVLRFNRADKANALNLQMWQDLRAALDWADAEPGVRAVVLAGHGKHFCAGIDLAMLVGLQSSIQD
ECEGRKRDKLRRVILDLQDCVNSLERCRKPVIAAIHGACLGGGLDIALAADFRFAAENAVFGVREVDLGMVADVGSLQRL
PRVVGEGVARELALTGRDMVAEEALEVGLVNRVAEDADAVLAAAMQSAKLIAGKSPLAVRGSKEVMNYSRDHSVADGLQF
VAGWNAAMLISEDIQKAGMAAMMKQQVSFRD
>Mature_271_residues
MINLQTVAVELDEKVAVLRFNRADKANALNLQMWQDLRAALDWADAEPGVRAVVLAGHGKHFCAGIDLAMLVGLQSSIQD
ECEGRKRDKLRRVILDLQDCVNSLERCRKPVIAAIHGACLGGGLDIALAADFRFAAENAVFGVREVDLGMVADVGSLQRL
PRVVGEGVARELALTGRDMVAEEALEVGLVNRVAEDADAVLAAAMQSAKLIAGKSPLAVRGSKEVMNYSRDHSVADGLQF
VAGWNAAMLISEDIQKAGMAAMMKQQVSFRD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=253, Percent_Identity=44.2687747035573, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI194097323, Length=269, Percent_Identity=30.1115241635688, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI20127408, Length=187, Percent_Identity=33.6898395721925, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=31.25, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI37594469, Length=264, Percent_Identity=27.6515151515151, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI37594471, Length=264, Percent_Identity=27.6515151515151, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI45643119, Length=223, Percent_Identity=26.457399103139, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260275230, Length=223, Percent_Identity=26.457399103139, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI260274832, Length=223, Percent_Identity=26.457399103139, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4502327, Length=248, Percent_Identity=30.241935483871, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221136756, Length=177, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI221136753, Length=177, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI221307494, Length=177, Percent_Identity=28.8135593220339, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116235487, Length=177, Percent_Identity=28.8135593220339, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI25453481, Length=172, Percent_Identity=26.1627906976744, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI51538573, Length=172, Percent_Identity=26.1627906976744, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4757966, Length=172, Percent_Identity=26.1627906976744, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI51538581, Length=172, Percent_Identity=26.1627906976744, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4757968, Length=172, Percent_Identity=26.1627906976744, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI49355787, Length=172, Percent_Identity=26.1627906976744, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI221142681, Length=219, Percent_Identity=33.7899543378995, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787659, Length=232, Percent_Identity=32.3275862068966, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788682, Length=226, Percent_Identity=33.6283185840708, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082183, Length=272, Percent_Identity=28.6764705882353, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=30, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790281, Length=230, Percent_Identity=26.5217391304348, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787660, Length=266, Percent_Identity=27.0676691729323, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=261, Percent_Identity=42.1455938697318, Blast_Score=234, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=42.5196850393701, Blast_Score=221, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17560910, Length=268, Percent_Identity=32.8358208955224, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17554946, Length=266, Percent_Identity=31.5789473684211, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=31.8897637795276, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=228, Percent_Identity=32.0175438596491, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17558304, Length=227, Percent_Identity=29.0748898678414, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=227, Percent_Identity=31.2775330396476, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=227, Percent_Identity=31.2775330396476, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=227, Percent_Identity=31.2775330396476, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=228, Percent_Identity=27.6315789473684, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540306, Length=203, Percent_Identity=32.512315270936, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144157, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=187, Percent_Identity=30.4812834224599, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=232, Percent_Identity=26.7241379310345, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=193, Percent_Identity=27.4611398963731, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19920382, Length=265, Percent_Identity=43.0188679245283, Blast_Score=211, Evalue=4e-55,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=31.8897637795276, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=31.8897637795276, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24653139, Length=230, Percent_Identity=31.7391304347826, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650670, Length=215, Percent_Identity=33.0232558139535, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357171, Length=210, Percent_Identity=32.8571428571429, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24583165, Length=221, Percent_Identity=27.1493212669683, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654903, Length=190, Percent_Identity=28.9473684210526, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921000, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583077, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583079, Length=198, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921018, Length=214, Percent_Identity=25.7009345794392, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29120; Mature: 29120

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLQTVAVELDEKVAVLRFNRADKANALNLQMWQDLRAALDWADAEPGVRAVVLAGHGK
CCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
HFCAGIDLAMLVGLQSSIQDECEGRKRDKLRRVILDLQDCVNSLERCRKPVIAAIHGACL
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLDIALAADFRFAAENAVFGVREVDLGMVADVGSLQRLPRVVGEGVARELALTGRDMV
CCCCEEEEECCHHHHHCCHHCCHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHH
AEEALEVGLVNRVAEDADAVLAAAMQSAKLIAGKSPLAVRGSKEVMNYSRDHSVADGLQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHCCCCCCCHHHHHHH
VAGWNAAMLISEDIQKAGMAAMMKQQVSFRD
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINLQTVAVELDEKVAVLRFNRADKANALNLQMWQDLRAALDWADAEPGVRAVVLAGHGK
CCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
HFCAGIDLAMLVGLQSSIQDECEGRKRDKLRRVILDLQDCVNSLERCRKPVIAAIHGACL
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLDIALAADFRFAAENAVFGVREVDLGMVADVGSLQRLPRVVGEGVARELALTGRDMV
CCCCEEEEECCHHHHHCCHHCCHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHH
AEEALEVGLVNRVAEDADAVLAAAMQSAKLIAGKSPLAVRGSKEVMNYSRDHSVADGLQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHCCCCCCCHHHHHHH
VAGWNAAMLISEDIQKAGMAAMMKQQVSFRD
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA