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The map label for this gene is ppa [H]

Identifier: 33863525

GI number: 33863525

Start: 1346769

End: 1347293

Strand: Reverse

Name: ppa [H]

Synonym: PMT1257

Alternate gene names: 33863525

Gene position: 1347293-1346769 (Counterclockwise)

Preceding gene: 33863526

Following gene: 33863524

Centisome position: 55.88

GC content: 51.62

Gene sequence:

>525_bases
ATGGATCTAAGCTCTCTACTCCCATCTCCTTCACCCGGGTTGGTCAACCTGTTGGTGGAGATTCCGGCGGGAAGCCGGAA
CAAGTACGAATATTTTGATGAGGCTGGTGTGATGGCCCTCGATAGGGTTCTTCATTCCTCGGTTCGCTACCCGTTTGATT
ACGGCTTCATCCCCAACACCCTTGCTGAAGATGGTGCACCTCTTGATGCAATGGTGATCATGGAGGAACCCACATTTGCT
GGCTGTCTGATTAGGGCACGACCAATCGGGGTGCTTGATATGCATGATTCCGGGGCTTATGACGGCAAGTTGTTGTGTGT
TCCCGTTGCTGATCCCCGTCAACGGTCGATCAGCAGCATTCGGCAGATTTCAGCCAGTCAACTGGAGGATGTGGCTGAAT
TCTTCCGCACTTACAAAAATCTTGAGGGGCGAGTTGTTGATATCGGTGGCTGGAGAGATTCAGAAGCTGTTGAGCCTCTG
TTGGAGACCTGCGCCAAAGCTGCGCAGGTTAAGCTGAAAAAGTAA

Upstream 100 bases:

>100_bases
TTGACTATTGCCATCGCAACCGTTGGATTACCCCTCGCGGCAGTTTTGACAGATCGGTCTGCGGGGAGGGAAAGCATGGT
TCCCACAGCCTTGGAGAAAG

Downstream 100 bases:

>100_bases
CTATGAACCCTAATCACTTGATTGAACGAGTTCATTCTTTGCTGGCCAGTTAAATCATGCTCAACTCAATAAGGATTTAT
AGCTATTCGCGCTGCGCTAC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDLSSLLPSPSPGLVNLLVEIPAGSRNKYEYFDEAGVMALDRVLHSSVRYPFDYGFIPNTLAEDGAPLDAMVIMEEPTFA
GCLIRARPIGVLDMHDSGAYDGKLLCVPVADPRQRSISSIRQISASQLEDVAEFFRTYKNLEGRVVDIGGWRDSEAVEPL
LETCAKAAQVKLKK

Sequences:

>Translated_174_residues
MDLSSLLPSPSPGLVNLLVEIPAGSRNKYEYFDEAGVMALDRVLHSSVRYPFDYGFIPNTLAEDGAPLDAMVIMEEPTFA
GCLIRARPIGVLDMHDSGAYDGKLLCVPVADPRQRSISSIRQISASQLEDVAEFFRTYKNLEGRVVDIGGWRDSEAVEPL
LETCAKAAQVKLKK
>Mature_174_residues
MDLSSLLPSPSPGLVNLLVEIPAGSRNKYEYFDEAGVMALDRVLHSSVRYPFDYGFIPNTLAEDGAPLDAMVIMEEPTFA
GCLIRARPIGVLDMHDSGAYDGKLLCVPVADPRQRSISSIRQISASQLEDVAEFFRTYKNLEGRVVDIGGWRDSEAVEPL
LETCAKAAQVKLKK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=162, Percent_Identity=35.8024691358025, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19103; Mature: 19103

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSSLLPSPSPGLVNLLVEIPAGSRNKYEYFDEAGVMALDRVLHSSVRYPFDYGFIPNT
CCHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCH
LAEDGAPLDAMVIMEEPTFAGCLIRARPIGVLDMHDSGAYDGKLLCVPVADPRQRSISSI
HHCCCCCCEEEEEEECCCCHHEEEEECCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
RQISASQLEDVAEFFRTYKNLEGRVVDIGGWRDSEAVEPLLETCAKAAQVKLKK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLSSLLPSPSPGLVNLLVEIPAGSRNKYEYFDEAGVMALDRVLHSSVRYPFDYGFIPNT
CCHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCH
LAEDGAPLDAMVIMEEPTFAGCLIRARPIGVLDMHDSGAYDGKLLCVPVADPRQRSISSI
HHCCCCCCEEEEEEECCCCHHEEEEECCCEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
RQISASQLEDVAEFFRTYKNLEGRVVDIGGWRDSEAVEPLLETCAKAAQVKLKK
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]