Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 33863441

GI number: 33863441

Start: 1263198

End: 1264001

Strand: Reverse

Name: ubiE [C]

Synonym: PMT1171

Alternate gene names: 33863441

Gene position: 1264001-1263198 (Counterclockwise)

Preceding gene: 33863442

Following gene: 33863439

Centisome position: 52.43

GC content: 55.6

Gene sequence:

>804_bases
ATGAGCAGTAGTTGCTGTAGTCCCTCTGCTTCAGGCCCTGGAGCTGATGCGTTAGATCAGACGCAGGCTGTAGAGGAGCG
CTATGGAGCTGCAGCGCATGCCCAGGAAGCTTGTTTGTGTACCCCGGTGGCTTTCGATCTCAGCCTGCTTAAGGCCATCC
CTCGTGAAGTTGTAGAGCGCGATTACGGCTGCGGTGACCCAACTCGATGGGTTAAGCCTGGTGACACTGTGCTTGATCTT
GGCAGTGGCAGTGGCAAGAACGCTTTTATTTGTGCCCAGCTGATCGGTTCGGCGGGTGCCGTGATTGGGGTGGATCGCAA
TGTTGAGATGCTCAACCTGGCTCGTCAGGCCGCACCAGTTGTGGCGGAGCGGATTGGCTTTGCCAATGTGCGCTTTGTCG
AGGGCGCTATCGAAGCGCTTGAAGCCCCTCAGGTTGATGGGTCTCCGCTTATTGCCGATCGGTCGATTGATGTGGTGTTG
AGCAACTGTGTGCTCAATTTGGTGAATCCTGCAGATCGTAAGAATCTGCTGGCCAACATTCGCAGGGTTTTGCGGCCAGG
TGGACGGCTTGCTGTTAGCGATATCGTCTGTGATAAGCCAGTACCCCTTGCTCTTCAGCAGGATCCGGAACTGTGGAGTG
GCTGCATTAGTGGGGCCTGGCAGGAAGAGGCCTTCCTGCAGGATTTTCGTGCTTTGGGCTTTGAGAAGGTGAGCTATGCC
GATCGTTCTGATCAACCCTGGCAGGTGGTTGAAGACATTGAATTTCGCGCCGTCACGCTTGTGGGTCAGCTGCCGGATGA
TTGA

Upstream 100 bases:

>100_bases
CTGGAGGCCTTGGGCTAATGCCCTTGGGTCATGCAGGTTTAGCCACCGATTCTTTCCCTGCCGACCACAATGGATTGATC
TTTCTTGAAGGGCTTGATTC

Downstream 100 bases:

>100_bases
GGAGGGACAGCAGGAGGTTGGTCTCTCTTGATGAGACCTGCCTCCATTGGCCAGGATCCATCCCTTCAATGCTGAGGGGT
GGCTCACCATCCATAAGCTC

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Domain Family; Methyltransferase-Like; UbiE/COQ5 Methyltransferase; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; Protein Containing Methyltransferase Domain; ArsR Family Transcriptional Regulator; SAM-Dependent Methyltransferases; UbiE/COQ5 Family Methlytransferase; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Transcriptional Regulator ArsR Family

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLKAIPREVVERDYGCGDPTRWVKPGDTVLDL
GSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGSPLIADRSIDVVL
SNCVLNLVNPADRKNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLQDFRALGFEKVSYA
DRSDQPWQVVEDIEFRAVTLVGQLPDD

Sequences:

>Translated_267_residues
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLKAIPREVVERDYGCGDPTRWVKPGDTVLDL
GSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGSPLIADRSIDVVL
SNCVLNLVNPADRKNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLQDFRALGFEKVSYA
DRSDQPWQVVEDIEFRAVTLVGQLPDD
>Mature_266_residues
SSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLKAIPREVVERDYGCGDPTRWVKPGDTVLDLG
SGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGSPLIADRSIDVVLS
NCVLNLVNPADRKNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLQDFRALGFEKVSYAD
RSDQPWQVVEDIEFRAVTLVGQLPDD

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=189, Percent_Identity=35.978835978836, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28504; Mature: 28373

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLKAIPREVVER
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCHHHHCHHHHHHHHHHHHHHHHHHH
DYGCGDPTRWVKPGDTVLDLGSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPV
CCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
VAERIGFANVRFVEGAIEALEAPQVDGSPLIADRSIDVVLSNCVLNLVNPADRKNLLANI
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLQDFRALGFEKVSYA
HHHHCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCC
DRSDQPWQVVEDIEFRAVTLVGQLPDD
CCCCCCHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure 
SSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLKAIPREVVER
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCHHHHCHHHHHHHHHHHHHHHHHHH
DYGCGDPTRWVKPGDTVLDLGSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPV
CCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
VAERIGFANVRFVEGAIEALEAPQVDGSPLIADRSIDVVLSNCVLNLVNPADRKNLLANI
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLQDFRALGFEKVSYA
HHHHCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCC
DRSDQPWQVVEDIEFRAVTLVGQLPDD
CCCCCCHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA