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The map label for this gene is zam [H]

Identifier: 33863038

GI number: 33863038

Start: 835005

End: 837398

Strand: Direct

Name: zam [H]

Synonym: PMT0766

Alternate gene names: 33863038

Gene position: 835005-837398 (Clockwise)

Preceding gene: 33863037

Following gene: 33863039

Centisome position: 34.63

GC content: 48.33

Gene sequence:

>2394_bases
ATGAAGTTCACGGTCGCTGACCTGCTTGACCAGTTACCCCCCACTGGGGGACTGGAGATCAAAAAACTCGAAAAAATTCT
CAAGCTCACCACAAAGGCCGATCGCGACGGTCTTGAAACAGCCCTTCAGGCTCTCTTGAAGCTCGGCATTGTCAACAACG
AAGAAGCCGGTGCAATAAAGCGTAGTGATGACGAGTCACTGATTGAAGCTCGTTTGCGCTGCAGCAGTAAAGGATTTTGC
TTTGCCCTAAGAGATGATGGGGGAGACGATATCTATATTCGCGATCATCAGCTCAACCATGCCTGGAACGGAGATCGGGT
ACTAGTCCGCATCACAAGAGATGGGGGACGTCGAAGATCGCCAGAAGGTGGTGTGCAATGCATCCTCGAAAGGAGCACCA
CCAGCTTGCTTGGTCATGTTGAACGCAAAGATCAAAATATCCTTGCAATACCTCTTGATGACCGCATCCTTGCAACGATC
CAACTGCCAGATGGTGATCAAGCCCATCTGAATGATGGGGAGCAGACAAGCGTGGTGGAGGTGAAGCTTGATCGCTATCC
CATTGCCCAGTTCCCCGCTGAAGGGCATGTAGCACGGTCACTTCCCTTGAATGGAGGCCCCTCAAGTGATCGTGATCTTC
TTCTTACCAAAGCCAACCTTCAAGATCGACCTGCTCCACCACGCAGCAGCCTAAAGACCCCAACGGCTAAACATCGGCAA
GATCTGAGCTCGCAACCAGCGTTGCTACTGCGTAGCTGGCAGGTATCTGATGCGCCACCCCTACCAGCGGTGTATGTGGA
GCCCCATGCAGGTGGCACACGTCTGTGGATTCATGCGCCTGCTGTAGCAGAACGTCTTACTATTGGGAACAACCTGGATC
TCTGGCTAAGAGATCGAGCGGAAGCTCTCTGCCTTGGAGAAGTTTGGCATCCCCTACTCGGCCAAATTCTTTCAAAAGCC
TGTTCATTTAAAGTTGGGGAAATCAACGATGCAGTAAGCGTTGCTCTCGACATCTCGGCAGATGGTGAGGTAACTAATTG
GCATTTCAGCCTTAGTTCAATCAAGCCAGTAGCCGAAATCGGACCTAAGACCCTCACAGCTCTTAGCAACAGAAAACCAA
AGGCAAGAACAGTCCCTGCTGCTCTGAAGCCCGTTAAGGATCACTTAGCCCAACTCGAGACATTAATCTTTTGTGCTCGT
ACATTGCAAATGGGAGAACAGGCCAGTGGCTCTATAGAGCTTGATCTGGCTGTTCCAGAACTTCAATGTCTTGGCGACCT
CCGCTGGGCAGACCCTGATTCATATCATCATCAATGGGCTCTTCCTCTTGATCAAACTGACCCCCAATCAGTTTTGAGCC
CAATGATTAGAGCTGCTCATCGTGCCTGGGCGCAACATGCCCAGAACTTGCAACTCCCTGGCCTGGTGATTGAGGCTTCA
GAAGCAGACAACAACACCTTGAACGACGTTGCTAAATCAGCATTAGCTCTTGATATTGCCTTGGAACTTGATGAAGAAGG
TAGACCTGCTGCCACAGAGCTTGCAAAAGCATTTTCGACAACAGCCTGTCGAAGAGTGCTGGATCAGCAACTACGCCATG
CACTGCCAGAAACTTTGTTAAGACTGGGAATTAATGATAGTCAGAAAGAGAATGGAAACATTGAATCCGACCATGAAGAC
ACAAAGACAAAGGATTCGAACCTACAATCACCTTGGTGCTGTCCAACTATCCATTACACCGATCTTGTTAATCAAGAGAT
CATAGTGACACTTTTAAGTAACGGTAAAGATCGTCCAAATGTCCGACAAAAGGAAAAAGTGGTTCTGGGGTCCCGTGAAT
GCTGGCAACAAATCAAGTGGCCACTATTCAGCACAAGCCAAGCAAAGAACCTAGAAGAAATTTGCAGTAAAAGCCTCGTG
CATCGCCTCAACACACTGCGCCGTCAAGCTGAAGAGCTTCGACAAGACCTGATCGCTATGGTTCAGGCACGTATCGTGGA
ACCCCTTGTTGGGGAAGAGCATCAGGGGGTGATAAGCGGAGTGCAGAGTTATGGGTTCTTTGTGGAAATTCCACCTTCTA
TGGCAGAGGGCCTTGTCCACGTCAGCTCTTTAAATGACGATTGGTACGAATATCGCTCACGTCAAAACCGATTGGTGGGT
CGGAAGAATCGCAAGATCTATCAACTTGGTGATCAAGTAAACGTTAAGGTTGTTAAAGTAGACGCCTTAAGAAACCAAAT
TGACCTCGAAGTCAATGGATCAGCAATAACTGTTGAAGCCAATATGAATGTTAATTCTGATCCAACCAATCAAGCAACAA
CAACAAAAAAAAGTGAGGTCAAAGGCAAAATCACCAAGAATAATGAACAACTAGTCAGCTCAAGTGAGGCATAG

Upstream 100 bases:

>100_bases
AATTAACTCACAGCCAATGTTGACTCTGCGCTGTCTTCGGATTCCTCTTTGGTGATGGCACCGCCGGTCATGAAGACTGG
TCTTCTACCTTCCTATCTCA

Downstream 100 bases:

>100_bases
TTTGTGGATCCCTATGTCCTTGCCGTATCTGGAGCATCAGCTCAACCTCTAGCTGAAAGATCGCTGCAGCTCTTGCTTGA
AAACAACCGTGACGTCCATT

Product: acetazolamide conferring resistance protein Zam

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MKFTVADLLDQLPPTGGLEIKKLEKILKLTTKADRDGLETALQALLKLGIVNNEEAGAIKRSDDESLIEARLRCSSKGFC
FALRDDGGDDIYIRDHQLNHAWNGDRVLVRITRDGGRRRSPEGGVQCILERSTTSLLGHVERKDQNILAIPLDDRILATI
QLPDGDQAHLNDGEQTSVVEVKLDRYPIAQFPAEGHVARSLPLNGGPSSDRDLLLTKANLQDRPAPPRSSLKTPTAKHRQ
DLSSQPALLLRSWQVSDAPPLPAVYVEPHAGGTRLWIHAPAVAERLTIGNNLDLWLRDRAEALCLGEVWHPLLGQILSKA
CSFKVGEINDAVSVALDISADGEVTNWHFSLSSIKPVAEIGPKTLTALSNRKPKARTVPAALKPVKDHLAQLETLIFCAR
TLQMGEQASGSIELDLAVPELQCLGDLRWADPDSYHHQWALPLDQTDPQSVLSPMIRAAHRAWAQHAQNLQLPGLVIEAS
EADNNTLNDVAKSALALDIALELDEEGRPAATELAKAFSTTACRRVLDQQLRHALPETLLRLGINDSQKENGNIESDHED
TKTKDSNLQSPWCCPTIHYTDLVNQEIIVTLLSNGKDRPNVRQKEKVVLGSRECWQQIKWPLFSTSQAKNLEEICSKSLV
HRLNTLRRQAEELRQDLIAMVQARIVEPLVGEEHQGVISGVQSYGFFVEIPPSMAEGLVHVSSLNDDWYEYRSRQNRLVG
RKNRKIYQLGDQVNVKVVKVDALRNQIDLEVNGSAITVEANMNVNSDPTNQATTTKKSEVKGKITKNNEQLVSSSEA

Sequences:

>Translated_797_residues
MKFTVADLLDQLPPTGGLEIKKLEKILKLTTKADRDGLETALQALLKLGIVNNEEAGAIKRSDDESLIEARLRCSSKGFC
FALRDDGGDDIYIRDHQLNHAWNGDRVLVRITRDGGRRRSPEGGVQCILERSTTSLLGHVERKDQNILAIPLDDRILATI
QLPDGDQAHLNDGEQTSVVEVKLDRYPIAQFPAEGHVARSLPLNGGPSSDRDLLLTKANLQDRPAPPRSSLKTPTAKHRQ
DLSSQPALLLRSWQVSDAPPLPAVYVEPHAGGTRLWIHAPAVAERLTIGNNLDLWLRDRAEALCLGEVWHPLLGQILSKA
CSFKVGEINDAVSVALDISADGEVTNWHFSLSSIKPVAEIGPKTLTALSNRKPKARTVPAALKPVKDHLAQLETLIFCAR
TLQMGEQASGSIELDLAVPELQCLGDLRWADPDSYHHQWALPLDQTDPQSVLSPMIRAAHRAWAQHAQNLQLPGLVIEAS
EADNNTLNDVAKSALALDIALELDEEGRPAATELAKAFSTTACRRVLDQQLRHALPETLLRLGINDSQKENGNIESDHED
TKTKDSNLQSPWCCPTIHYTDLVNQEIIVTLLSNGKDRPNVRQKEKVVLGSRECWQQIKWPLFSTSQAKNLEEICSKSLV
HRLNTLRRQAEELRQDLIAMVQARIVEPLVGEEHQGVISGVQSYGFFVEIPPSMAEGLVHVSSLNDDWYEYRSRQNRLVG
RKNRKIYQLGDQVNVKVVKVDALRNQIDLEVNGSAITVEANMNVNSDPTNQATTTKKSEVKGKITKNNEQLVSSSEA
>Mature_797_residues
MKFTVADLLDQLPPTGGLEIKKLEKILKLTTKADRDGLETALQALLKLGIVNNEEAGAIKRSDDESLIEARLRCSSKGFC
FALRDDGGDDIYIRDHQLNHAWNGDRVLVRITRDGGRRRSPEGGVQCILERSTTSLLGHVERKDQNILAIPLDDRILATI
QLPDGDQAHLNDGEQTSVVEVKLDRYPIAQFPAEGHVARSLPLNGGPSSDRDLLLTKANLQDRPAPPRSSLKTPTAKHRQ
DLSSQPALLLRSWQVSDAPPLPAVYVEPHAGGTRLWIHAPAVAERLTIGNNLDLWLRDRAEALCLGEVWHPLLGQILSKA
CSFKVGEINDAVSVALDISADGEVTNWHFSLSSIKPVAEIGPKTLTALSNRKPKARTVPAALKPVKDHLAQLETLIFCAR
TLQMGEQASGSIELDLAVPELQCLGDLRWADPDSYHHQWALPLDQTDPQSVLSPMIRAAHRAWAQHAQNLQLPGLVIEAS
EADNNTLNDVAKSALALDIALELDEEGRPAATELAKAFSTTACRRVLDQQLRHALPETLLRLGINDSQKENGNIESDHED
TKTKDSNLQSPWCCPTIHYTDLVNQEIIVTLLSNGKDRPNVRQKEKVVLGSRECWQQIKWPLFSTSQAKNLEEICSKSLV
HRLNTLRRQAEELRQDLIAMVQARIVEPLVGEEHQGVISGVQSYGFFVEIPPSMAEGLVHVSSLNDDWYEYRSRQNRLVG
RKNRKIYQLGDQVNVKVVKVDALRNQIDLEVNGSAITVEANMNVNSDPTNQATTTKKSEVKGKITKNNEQLVSSSEA

Specific function: Not known; control resistance to the carbonic anhydrase inhibitor acetazolamide [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=769, Percent_Identity=22.2366710013004, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 88196; Mature: 88196

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTVADLLDQLPPTGGLEIKKLEKILKLTTKADRDGLETALQALLKLGIVNNEEAGAIK
CCEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RSDDESLIEARLRCSSKGFCFALRDDGGDDIYIRDHQLNHAWNGDRVLVRITRDGGRRRS
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PEGGVQCILERSTTSLLGHVERKDQNILAIPLDDRILATIQLPDGDQAHLNDGEQTSVVE
CCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEE
VKLDRYPIAQFPAEGHVARSLPLNGGPSSDRDLLLTKANLQDRPAPPRSSLKTPTAKHRQ
EEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
DLSSQPALLLRSWQVSDAPPLPAVYVEPHAGGTRLWIHAPAVAERLTIGNNLDLWLRDRA
CCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEECCHHHHHHCCCCCCCEEECCCC
EALCLGEVWHPLLGQILSKACSFKVGEINDAVSVALDISADGEVTNWHFSLSSIKPVAEI
HHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEEEEECCCCCEEEEEEECCCCCHHHHC
GPKTLTALSNRKPKARTVPAALKPVKDHLAQLETLIFCARTLQMGEQASGSIELDLAVPE
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
LQCLGDLRWADPDSYHHQWALPLDQTDPQSVLSPMIRAAHRAWAQHAQNLQLPGLVIEAS
HHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
EADNNTLNDVAKSALALDIALELDEEGRPAATELAKAFSTTACRRVLDQQLRHALPETLL
CCCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGINDSQKENGNIESDHEDTKTKDSNLQSPWCCPTIHYTDLVNQEIIVTLLSNGKDRPN
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHEEEEECCCCCCCC
VRQKEKVVLGSRECWQQIKWPLFSTSQAKNLEEICSKSLVHRLNTLRRQAEELRQDLIAM
CCHHHHHEECCHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQARIVEPLVGEEHQGVISGVQSYGFFVEIPPSMAEGLVHVSSLNDDWYEYRSRQNRLVG
HHHHHHHHHCCCCCHHHHHHHHHCCEEEEECHHHHHHEEEEECCCHHHHHHHHHHHCCCC
RKNRKIYQLGDQVNVKVVKVDALRNQIDLEVNGSAITVEANMNVNSDPTNQATTTKKSEV
CCCCEEEECCCCCEEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHC
KGKITKNNEQLVSSSEA
CCEEECCCHHHHCCCCC
>Mature Secondary Structure
MKFTVADLLDQLPPTGGLEIKKLEKILKLTTKADRDGLETALQALLKLGIVNNEEAGAIK
CCEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RSDDESLIEARLRCSSKGFCFALRDDGGDDIYIRDHQLNHAWNGDRVLVRITRDGGRRRS
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PEGGVQCILERSTTSLLGHVERKDQNILAIPLDDRILATIQLPDGDQAHLNDGEQTSVVE
CCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEE
VKLDRYPIAQFPAEGHVARSLPLNGGPSSDRDLLLTKANLQDRPAPPRSSLKTPTAKHRQ
EEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
DLSSQPALLLRSWQVSDAPPLPAVYVEPHAGGTRLWIHAPAVAERLTIGNNLDLWLRDRA
CCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEECCHHHHHHCCCCCCCEEECCCC
EALCLGEVWHPLLGQILSKACSFKVGEINDAVSVALDISADGEVTNWHFSLSSIKPVAEI
HHHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEEEEECCCCCEEEEEEECCCCCHHHHC
GPKTLTALSNRKPKARTVPAALKPVKDHLAQLETLIFCARTLQMGEQASGSIELDLAVPE
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
LQCLGDLRWADPDSYHHQWALPLDQTDPQSVLSPMIRAAHRAWAQHAQNLQLPGLVIEAS
HHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
EADNNTLNDVAKSALALDIALELDEEGRPAATELAKAFSTTACRRVLDQQLRHALPETLL
CCCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLGINDSQKENGNIESDHEDTKTKDSNLQSPWCCPTIHYTDLVNQEIIVTLLSNGKDRPN
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHEEEEECCCCCCCC
VRQKEKVVLGSRECWQQIKWPLFSTSQAKNLEEICSKSLVHRLNTLRRQAEELRQDLIAM
CCHHHHHEECCHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQARIVEPLVGEEHQGVISGVQSYGFFVEIPPSMAEGLVHVSSLNDDWYEYRSRQNRLVG
HHHHHHHHHCCCCCHHHHHHHHHCCEEEEECHHHHHHEEEEECCCHHHHHHHHHHHCCCC
RKNRKIYQLGDQVNVKVVKVDALRNQIDLEVNGSAITVEANMNVNSDPTNQATTTKKSEV
CCCCEEEECCCCCEEEEEEEECCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCHHHC
KGKITKNNEQLVSSSEA
CCEEECCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7727754; 8905231 [H]