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The map label for this gene is aroB [H]

Identifier: 33862939

GI number: 33862939

Start: 723683

End: 724801

Strand: Reverse

Name: aroB [H]

Synonym: PMT0667

Alternate gene names: 33862939

Gene position: 724801-723683 (Counterclockwise)

Preceding gene: 33862942

Following gene: 33862937

Centisome position: 30.06

GC content: 52.9

Gene sequence:

>1119_bases
ATGTCCGCTTTCGTGAATATCGACGCCCAACGCATCCCAGTAGCACTGAGCCACCAGCCCTACGAGGTGGTCATTGGGGG
GGAAGGCTTGCGGGGTGTTGGTAAGGAGCTTCGCCGTGCTGGGCTGAAAGAGGGAATCAAGGTATTGGTTGTAAGCAATG
CTGATGTTGCTGAGCCATATGGTGATCTTTGCCTCCAAAGCCTTAAGGAGAGCGGTTTCAGGCCCACTCTGCTGGTGATC
GAGGCCGGAGAAGATCAAAAGACGCCAGTGAGCGTGGCGTTAATTCACGATGCAGCCTATGAAGCAAAGCTAGAAAGAGG
ATCCTTGATGGTTGCTCTTGGCGGTGGGGTAGTGGGCGACATGACTGGATTTGCAGCAGCTACTTGGCTAAGAGGTATCT
CGGTGGTGCAACTTCCTACAACCCTTCTGGCAATGGTGGATGCCGCGATTGGTGGCAAGACAGGCGTCAATCACCCGGGC
GGAAAAAATCTGATCGGAGCATTTCACCAACCAAGGCTTGTATTAATCGATCCCTCAACTCTGAAAACATTGCCAGAACG
TGAATTCCGGGCAGGGATGGCCGAAGTGATCAAATACGGGGTGATCGGTGATTCAGCACTTTTTCAACTCCTAGAAGGCA
TTCAAGAACTAGACACACCATCACAACTCCATCAAGACCTTCTGGAGAAAATTCTCGAACGTTCAGCACTCGCGAAGTCG
AGAGTGGTGAGCTCAGATGAACGAGAGGGCGGGCTGCGCGCCATCCTTAACTACGGGCACACCTTCGGGCATGTGGTGGA
AACCCTCTGTGGCTATGGAAACTGGCTGCATGGTGAAGCTGTCGCCATCGGCATGGTGGCGGTTGGGGAGCTGGCGGTGT
TGCGACAGAGCTGGAGCAGGGATGATGCCAACAGGCAAAAGTCGCTGATCGCAAAGGCAGGGCTGCCGATTGCTTGGCCC
AAGCTAGATCCAGAGGAGGTGCTGTATACCCTGCAAGGGGATAAAAAGGTCAAAGATGGAAAGCTTCGCTTTGTGATTCC
CACCGGCATTGGCAACGTCGAAATCAAAAATGACGTAAGCAGAGAAGAAATCCGAAAATGCCTATCAGAGCTCAGCTAA

Upstream 100 bases:

>100_bases
ACAGAGGACCAGCCATCACCACAATGCCTGTACTGACAGGAGATTACGTGGGAGCGTTTGATGCCACCCGGCAAACTGAG
ATCAGCAGACTTGCTCTTTC

Downstream 100 bases:

>100_bases
CTGGGTCCTCTAGGAACCGGCAGCGAAGTTCACCGACCTCAGCATCAAGAGATGGTTTGGGCCTCAAATCAAAAGCCAAC
CAACGAAACTCTCCCAAGCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSAFVNIDAQRIPVALSHQPYEVVIGGEGLRGVGKELRRAGLKEGIKVLVVSNADVAEPYGDLCLQSLKESGFRPTLLVI
EAGEDQKTPVSVALIHDAAYEAKLERGSLMVALGGGVVGDMTGFAAATWLRGISVVQLPTTLLAMVDAAIGGKTGVNHPG
GKNLIGAFHQPRLVLIDPSTLKTLPEREFRAGMAEVIKYGVIGDSALFQLLEGIQELDTPSQLHQDLLEKILERSALAKS
RVVSSDEREGGLRAILNYGHTFGHVVETLCGYGNWLHGEAVAIGMVAVGELAVLRQSWSRDDANRQKSLIAKAGLPIAWP
KLDPEEVLYTLQGDKKVKDGKLRFVIPTGIGNVEIKNDVSREEIRKCLSELS

Sequences:

>Translated_372_residues
MSAFVNIDAQRIPVALSHQPYEVVIGGEGLRGVGKELRRAGLKEGIKVLVVSNADVAEPYGDLCLQSLKESGFRPTLLVI
EAGEDQKTPVSVALIHDAAYEAKLERGSLMVALGGGVVGDMTGFAAATWLRGISVVQLPTTLLAMVDAAIGGKTGVNHPG
GKNLIGAFHQPRLVLIDPSTLKTLPEREFRAGMAEVIKYGVIGDSALFQLLEGIQELDTPSQLHQDLLEKILERSALAKS
RVVSSDEREGGLRAILNYGHTFGHVVETLCGYGNWLHGEAVAIGMVAVGELAVLRQSWSRDDANRQKSLIAKAGLPIAWP
KLDPEEVLYTLQGDKKVKDGKLRFVIPTGIGNVEIKNDVSREEIRKCLSELS
>Mature_371_residues
SAFVNIDAQRIPVALSHQPYEVVIGGEGLRGVGKELRRAGLKEGIKVLVVSNADVAEPYGDLCLQSLKESGFRPTLLVIE
AGEDQKTPVSVALIHDAAYEAKLERGSLMVALGGGVVGDMTGFAAATWLRGISVVQLPTTLLAMVDAAIGGKTGVNHPGG
KNLIGAFHQPRLVLIDPSTLKTLPEREFRAGMAEVIKYGVIGDSALFQLLEGIQELDTPSQLHQDLLEKILERSALAKSR
VVSSDEREGGLRAILNYGHTFGHVVETLCGYGNWLHGEAVAIGMVAVGELAVLRQSWSRDDANRQKSLIAKAGLPIAWPK
LDPEEVLYTLQGDKKVKDGKLRFVIPTGIGNVEIKNDVSREEIRKCLSELS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=41.7127071823204, Blast_Score=256, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6320332, Length=353, Percent_Identity=37.3937677053824, Blast_Score=190, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40022; Mature: 39891

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFVNIDAQRIPVALSHQPYEVVIGGEGLRGVGKELRRAGLKEGIKVLVVSNADVAEPY
CCCEEECCHHHCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
GDLCLQSLKESGFRPTLLVIEAGEDQKTPVSVALIHDAAYEAKLERGSLMVALGGGVVGD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEECCCCHHH
MTGFAAATWLRGISVVQLPTTLLAMVDAAIGGKTGVNHPGGKNLIGAFHQPRLVLIDPST
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEECCHH
LKTLPEREFRAGMAEVIKYGVIGDSALFQLLEGIQELDTPSQLHQDLLEKILERSALAKS
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RVVSSDEREGGLRAILNYGHTFGHVVETLCGYGNWLHGEAVAIGMVAVGELAVLRQSWSR
HHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DDANRQKSLIAKAGLPIAWPKLDPEEVLYTLQGDKKVKDGKLRFVIPTGIGNVEIKNDVS
CHHHHHHHHHHHCCCCEECCCCCHHHHEEEECCCCEECCCEEEEEEECCCCCEEECCCCC
REEIRKCLSELS
HHHHHHHHHHCC
>Mature Secondary Structure 
SAFVNIDAQRIPVALSHQPYEVVIGGEGLRGVGKELRRAGLKEGIKVLVVSNADVAEPY
CCEEECCHHHCCEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCH
GDLCLQSLKESGFRPTLLVIEAGEDQKTPVSVALIHDAAYEAKLERGSLMVALGGGVVGD
HHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHHHHCCCCEEEEECCCCHHH
MTGFAAATWLRGISVVQLPTTLLAMVDAAIGGKTGVNHPGGKNLIGAFHQPRLVLIDPST
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEEEEECCHH
LKTLPEREFRAGMAEVIKYGVIGDSALFQLLEGIQELDTPSQLHQDLLEKILERSALAKS
HHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RVVSSDEREGGLRAILNYGHTFGHVVETLCGYGNWLHGEAVAIGMVAVGELAVLRQSWSR
HHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DDANRQKSLIAKAGLPIAWPKLDPEEVLYTLQGDKKVKDGKLRFVIPTGIGNVEIKNDVS
CHHHHHHHHHHHCCCCEECCCCCHHHHEEEECCCCEECCCEEEEEEECCCCCEEECCCCC
REEIRKCLSELS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA