| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is pcnB
Identifier: 304570488
GI number: 304570488
Start: 1315075
End: 1316538
Strand: Direct
Name: pcnB
Synonym: NA
Alternate gene names: 304570488
Gene position: 1315075-1316538 (Clockwise)
Preceding gene: 45656946
Following gene: 45656953
Centisome position: 30.75
GC content: 36.82
Gene sequence:
>1464_bases ATGAAATTCCTGTCCAATCTGTTCAAGAAAAAAATAGGATCAGTTGAGGATATTCTCTCGCACCCGGACGGTAAACGTTA TTATCGGGATGCTCATCTGATCCGTAAAAACATGATAGATGAGGACGCGGTCAAAATCATCCATAGGCTGAATAAATTTG GTTTTAAGGCTTATATCGTAGGGGGGGGGGTTCGAGATCTTCTTCTCGGAAGAAAACCGAAGGATTTCGATGTTGTCACT AACGCGACCCCGAATCAGATCAAAAAGATCTTCAATAATTGTAGAATCATCGGAAGAAGATTCAAAATTGTGCATATACT TTTCCGTGGGAAAGTAATCGAAGTCAGTACCTTTCGTTCCTTGCCTGATTATAGATTGGGAAAAGCTGTAGAGGATCAAG ATTATCTAATCAAGAGAGATAATAAATTTGGCACACCTCAGGAAGACGCGGCTCGCAGAGACTTTACAATCAATTCTTTA TATTATGACGTAAGAAACGACTCCATAATAGACTATGTAGGCGGCTTTGAGGATATTCGAAATAAAGTATTAAGAGTGAT CGGAGATCCGGATATTTCTTTTCGAGAAGATCCTGTGAGGATGTTACGGGCTGTAAAGTTTGCAGAAATTTTAGGACTCA ATATTGAAAAGACAACCGCCAAGGCGATTCGTAAACATAAGACAGAATTAGAAAAAGCTTCTAGTTCCAGAATGTTAGAA GAATACAATAAGATCTTTCGCACTTGGAAAACTTCCTTGATTTTTCAAGGAATGGCGGAACACGGAATTTTAGAAGTTCT TTTTAAAGAAGCCTTTGATAAGGAAAGAAAAAAGAATTCCAATTTTGGTGAGAAATTTTTAGAAACCAATATCGGAAAAC GACTCGCGATTGCGGATAAGTTACTGACTGAAAGGGAGGAGATGACTCCTCATATATTTTATTCTTTAATTTTTTCAGAT CTCGCTTCGGAAGCATTACAAAAAGAGAATATGCATTTGGTTCCAGCGATCAAAAATAGTTTGGAACTGATTTTTAGACG ACTGGAAACTCCTAAAAAAGATAAAGATCGTTTAATTAAGATTTTTGCAAGTCAACAGAGATTTTTAAGTACAGAAGACG AAAAGTCTTCTCAAAATAATTTCTTTCGGATGAAGGATTATTTTTACGATGCCTTTATGGTATTTAAAATTGGAGCGATC GCGGAAAACGATGAAAAGGCGATTCAGAGCGCGTTTTTCTGGGAAATTTCTGTGAGAAAAAGACCAACTCCCGTAAAAAA ATTCAACGGGGCTCGCCCTAATAAAAGTAGAAATCGAAATTTTCAGAAAAATCGGGAAGAAGATCGTTCCAATCGAAGGG AAGAAACTCAAAGTTCTTCTGAATCGGAAAAACAGAATCGCAAAAATCAGAAGGAAAATTCTCAAGAAGATTTTTCTTCT GAAGATTCAGGAAATGAATTTTAG
Upstream 100 bases:
NA
Downstream 100 bases:
NA
Product: poly A polymerase
Products: NA
Alternate protein names: PAP; Plasmid copy number protein [H]
Number of amino acids: Translated: 487; Mature: 487
Protein sequence:
NA
Sequences:
>Translated_487_residues MKFLSNLFKKKIGSVEDILSHPDGKRYYRDAHLIRKNMIDEDAVKIIHRLNKFGFKAYIVGGGVRDLLLGRKPKDFDVVT NATPNQIKKIFNNCRIIGRRFKIVHILFRGKVIEVSTFRSLPDYRLGKAVEDQDYLIKRDNKFGTPQEDAARRDFTINSL YYDVRNDSIIDYVGGFEDIRNKVLRVIGDPDISFREDPVRMLRAVKFAEILGLNIEKTTAKAIRKHKTELEKASSSRMLE EYNKIFRTWKTSLIFQGMAEHGILEVLFKEAFDKERKKNSNFGEKFLETNIGKRLAIADKLLTEREEMTPHIFYSLIFSD LASEALQKENMHLVPAIKNSLELIFRRLETPKKDKDRLIKIFASQQRFLSTEDEKSSQNNFFRMKDYFYDAFMVFKIGAI AENDEKAIQSAFFWEISVRKRPTPVKKFNGARPNKSRNRNFQKNREEDRSNRREETQSSSESEKQNRKNQKENSQEDFSS EDSGNEF >Mature_487_residues MKFLSNLFKKKIGSVEDILSHPDGKRYYRDAHLIRKNMIDEDAVKIIHRLNKFGFKAYIVGGGVRDLLLGRKPKDFDVVT NATPNQIKKIFNNCRIIGRRFKIVHILFRGKVIEVSTFRSLPDYRLGKAVEDQDYLIKRDNKFGTPQEDAARRDFTINSL YYDVRNDSIIDYVGGFEDIRNKVLRVIGDPDISFREDPVRMLRAVKFAEILGLNIEKTTAKAIRKHKTELEKASSSRMLE EYNKIFRTWKTSLIFQGMAEHGILEVLFKEAFDKERKKNSNFGEKFLETNIGKRLAIADKLLTEREEMTPHIFYSLIFSD LASEALQKENMHLVPAIKNSLELIFRRLETPKKDKDRLIKIFASQQRFLSTEDEKSSQNNFFRMKDYFYDAFMVFKIGAI AENDEKAIQSAFFWEISVRKRPTPVKKFNGARPNKSRNRNFQKNREEDRSNRREETQSSSESEKQNRKNQKENSQEDFSS EDSGNEF
Specific function: Polymerase that creates the 3' poly(A) tail found in some mRNA's. Seems to be involved in plasmid copy number control [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family [H]
Homologues:
Organism=Homo sapiens, GI155030240, Length=201, Percent_Identity=32.3383084577114, Blast_Score=85, Evalue=1e-16, Organism=Escherichia coli, GI87081691, Length=269, Percent_Identity=43.4944237918216, Blast_Score=245, Evalue=4e-66, Organism=Escherichia coli, GI1789436, Length=226, Percent_Identity=31.858407079646, Blast_Score=86, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71995920, Length=224, Percent_Identity=29.4642857142857, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI281360112, Length=211, Percent_Identity=30.8056872037915, Blast_Score=89, Evalue=7e-18, Organism=Drosophila melanogaster, GI21357337, Length=211, Percent_Identity=30.8056872037915, Blast_Score=89, Evalue=7e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002646 - InterPro: IPR010206 [H]
Pfam domain/function: PF01743 PolyA_pol [H]
EC number: =2.7.7.19 [H]
Molecular weight: Translated: 57090; Mature: 57090
Theoretical pI: Translated: 10.23; Mature: 10.23
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKFLSNLFKKKIGSVEDILSHPDGKRYYRDAHLIRKNMIDEDAVKIIHRLNKFGFKAYIV CHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE GGGVRDLLLGRKPKDFDVVTNATPNQIKKIFNNCRIIGRRFKIVHILFRGKVIEVSTFRS CCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEHHHHC LPDYRLGKAVEDQDYLIKRDNKFGTPQEDAARRDFTINSLYYDVRNDSIIDYVGGFEDIR CCCHHHCCCCCCCCHHEECCCCCCCCCHHHHHCCCCHHHEEEECCCCCHHHHHCCHHHHH NKVLRVIGDPDISFREDPVRMLRAVKFAEILGLNIEKTTAKAIRKHKTELEKASSSRMLE HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH EYNKIFRTWKTSLIFQGMAEHGILEVLFKEAFDKERKKNSNFGEKFLETNIGKRLAIADK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH LLTEREEMTPHIFYSLIFSDLASEALQKENMHLVPAIKNSLELIFRRLETPKKDKDRLIK HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCCHHHHHHH IFASQQRFLSTEDEKSSQNNFFRMKDYFYDAFMVFKIGAIAENDEKAIQSAFFWEISVRK HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCC RPTPVKKFNGARPNKSRNRNFQKNREEDRSNRREETQSSSESEKQNRKNQKENSQEDFSS CCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC EDSGNEF CCCCCCC >Mature Secondary Structure MKFLSNLFKKKIGSVEDILSHPDGKRYYRDAHLIRKNMIDEDAVKIIHRLNKFGFKAYIV CHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEE GGGVRDLLLGRKPKDFDVVTNATPNQIKKIFNNCRIIGRRFKIVHILFRGKVIEVSTFRS CCCHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEHHHHC LPDYRLGKAVEDQDYLIKRDNKFGTPQEDAARRDFTINSLYYDVRNDSIIDYVGGFEDIR CCCHHHCCCCCCCCHHEECCCCCCCCCHHHHHCCCCHHHEEEECCCCCHHHHHCCHHHHH NKVLRVIGDPDISFREDPVRMLRAVKFAEILGLNIEKTTAKAIRKHKTELEKASSSRMLE HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH EYNKIFRTWKTSLIFQGMAEHGILEVLFKEAFDKERKKNSNFGEKFLETNIGKRLAIADK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHH LLTEREEMTPHIFYSLIFSDLASEALQKENMHLVPAIKNSLELIFRRLETPKKDKDRLIK HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCCHHHHHHH IFASQQRFLSTEDEKSSQNNFFRMKDYFYDAFMVFKIGAIAENDEKAIQSAFFWEISVRK HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCC RPTPVKKFNGARPNKSRNRNFQKNREEDRSNRREETQSSSESEKQNRKNQKENSQEDFSS CCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC EDSGNEF CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]