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The map label for this gene is narA-2

Identifier: 30263518

GI number: 30263518

Start: 3330632

End: 3331648

Strand: Reverse

Name: narA-2

Synonym: BA_3627

Alternate gene names: 30263518

Gene position: 3331648-3330632 (Counterclockwise)

Preceding gene: 30263519

Following gene: 30263517

Centisome position: 63.74

GC content: 35.89

Gene sequence:

>1017_bases
ATGAAATCTGTCACATTAGACAAACTACAACGTCCGTTAAAGGATTTACGTATTTCAGTTACTGATCGCTGTAATTTTCG
CTGTCGATATTGTATGCCAGAAGAAATATTTGGTCCGGATTACTCGTTTTTGTCTAATGATAAAATTTTATCTTTTGATG
AAATTGAAAGGATAACGCGTATTTTCGTTTCTTTAGGTGTTAGAAAATTACGGATTACAGGCGGAGAACCGTTACTTCGA
AGAGGTCTTCCACAGCTTATTGAGCGTCTTAATAAAGTAGATGGTGTAGAGGATATTGGCTTAACAACCAATGGATCGTT
ACTTAAAAAGTTTGCTCCTGATTTATATAAGGCGGGTTTATCACGTGTGACAGTTAGTTTAGATTCCTTAGAAGAAGAGC
GGTTTTTCTATTTAAATGGTAATAGAAGCAAAGTACAAAGGGTTCTGGAAGGCATACAAGCTGCAGCTGAAGTTGGAATG
AAAATTAAAATAAACATGGTCGTTCAAAAGGGGAAAAACGAACAGGACATCTTGCAGATGGCACAATACTTTAAGGAAAA
CAAACATATTCTTCGTTTTATTGAGTATATGGACGTTGGAAATTATAATGGTTGGGAGTTAAAAGAGGTCGTATCTAAAC
AAGAAATAGTAGATATGATTCATCAAGTTATGCCATTAGAACGGATAGAAGCGAATTATGCAGGTGAGGTTGCGACTCGC
TATAGTTATATTGGAAGTGATGAAGAAATAGGTGTTATTTCATCAGTAACAGATTCTTTCTGCTCTTCATGTACGAGAGC
TCGTATTTCTGCAGAAGGAAAATTATATACTTGTTTATTCGCTTCTAAAGGAAATGACTTGAGAGAACTGCTTCGATCTG
ACTACACTGACGAGGAAATAACAGATGTCGTACGCGACATATGGAACAACCGAGAAGATCGTTATTCAGATGAACGGTTA
AGTAATAGTAATAAAAAAGCTATGCCTAAAATTGAAATGTCACATATCGGTGGTTAA

Upstream 100 bases:

>100_bases
GTATTACTACGATAGGATTTATTCGGAATCAATCCTTAAATGTATATACGCACCCAGAGCGTGTTTTAAATATAAAATAA
GTAAAAGCGAGGCAATAAAT

Downstream 100 bases:

>100_bases
TATAAAGTTGACATAAAAGTGAAAAATGGAAGGTGTACAAGAATTGTAGATTTTCTATTTTATAGTAAAAGTGATGATTG
ATCTCTCTGTAAAAGATGTG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPQLIERLNKVDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWELKEVVSKQEIVDMIHQVMPLERIEANYAGEVATR
YSYIGSDEEIGVISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSDYTDEEITDVVRDIWNNREDRYSDERL
SNSNKKAMPKIEMSHIGG

Sequences:

>Translated_338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPQLIERLNKVDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWELKEVVSKQEIVDMIHQVMPLERIEANYAGEVATR
YSYIGSDEEIGVISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSDYTDEEITDVVRDIWNNREDRYSDERL
SNSNKKAMPKIEMSHIGG
>Mature_338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPQLIERLNKVDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWELKEVVSKQEIVDMIHQVMPLERIEANYAGEVATR
YSYIGSDEEIGVISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSDYTDEEITDVVRDIWNNREDRYSDERL
SNSNKKAMPKIEMSHIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family

Homologues:

Organism=Homo sapiens, GI116734668, Length=334, Percent_Identity=35.9281437125749, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI22027536, Length=334, Percent_Identity=35.9281437125749, Blast_Score=202, Evalue=4e-52,
Organism=Escherichia coli, GI1786999, Length=307, Percent_Identity=36.1563517915309, Blast_Score=184, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI32566329, Length=334, Percent_Identity=32.6347305389222, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32566331, Length=327, Percent_Identity=32.7217125382263, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17561210, Length=334, Percent_Identity=33.2335329341317, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI28574490, Length=312, Percent_Identity=33.6538461538462, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28574488, Length=303, Percent_Identity=34.6534653465347, Blast_Score=194, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAA_BACAC (C3LA56)

Other databases:

- EMBL:   CP001215
- RefSeq:   YP_002813611.1
- ProteinModelPortal:   C3LA56
- SMR:   C3LA56
- EnsemblBacteria:   EBBACT00000118740
- GeneID:   7786939
- GenomeReviews:   CP001215_GR
- KEGG:   bah:BAMEG_1006
- GeneTree:   EBGT00050000002384
- ProtClustDB:   CLSK584613
- HAMAP:   MF_01225_B
- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00729
- TIGRFAMs:   TIGR02666

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 38790; Mature: 38790

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: BINDING 17-17 BINDING 30-30 BINDING 71-71 BINDING 75-75 BINDING 102-102 BINDING 126-126 BINDING 163-163 BINDING 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITR
CCCCCHHHHHHHHHHCEEEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
IFVSLGVRKLRITGGEPLLRRGLPQLIERLNKVDGVEDIGLTTNGSLLKKFAPDLYKAGL
HHHHHCCEEEEECCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHCCH
SRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGMKIKINMVVQKGKNEQDILQM
HHEEHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
AQYFKENKHILRFIEYMDVGNYNGWELKEVVSKQEIVDMIHQVMPLERIEANYAGEVATR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHH
YSYIGSDEEIGVISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSDYTDEEI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCHHHH
TDVVRDIWNNREDRYSDERLSNSNKKAMPKIEMSHIGG
HHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITR
CCCCCHHHHHHHHHHCEEEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
IFVSLGVRKLRITGGEPLLRRGLPQLIERLNKVDGVEDIGLTTNGSLLKKFAPDLYKAGL
HHHHHCCEEEEECCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHCCH
SRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGMKIKINMVVQKGKNEQDILQM
HHEEHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
AQYFKENKHILRFIEYMDVGNYNGWELKEVVSKQEIVDMIHQVMPLERIEANYAGEVATR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHH
YSYIGSDEEIGVISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSDYTDEEI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCHHHH
TDVVRDIWNNREDRYSDERLSNSNKKAMPKIEMSHIGG
HHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA