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The map label for this gene is namA

Identifier: 30262063

GI number: 30262063

Start: 1912101

End: 1913138

Strand: Reverse

Name: namA

Synonym: BA_2038

Alternate gene names: 30262063

Gene position: 1913138-1912101 (Counterclockwise)

Preceding gene: 30262070

Following gene: 30262060

Centisome position: 36.6

GC content: 39.21

Gene sequence:

>1038_bases
ATGAATTCCGAACTTTTTTCACCTTATACAATTAAGGACGTTACATTAAAAAACCGAATTGTTATGTCACCTATGTGCAT
GTATTCATCGGAAAACGAGGATGGCCAAGTAACGAATTTCCATCTCATTCATTATGGAACGAGAGCGGCTGGTCAAGTTG
GTTTAGTTATGATTGAAGCAACAGCCGTATTACCTGAAGGGCGAATTTCTAATAAAGACTTAGGTATTTGGGATGACAGT
CTAATTGAAGGCTTACATAAAACGACAACTTTTATACATGATAACGGTGCAAAAGCTGCCATTCAACTCGCTCACGCTGG
AAGAAAAGCTGAATTAGAAACGGATGCTCTCGCTCCATCCGCAGTTCCGTTTAATGAAACTATGAAAATACCAGTAGAAA
TGAGTATACATCAAATAAAAAATACCATATTAGCGTTTCAGCAGGCTGCAATACGATCAAAACAAGCTGGATTTGACGTG
ATTGAAATACATGGCGCCCACGGTTATCTCATTAATGAATTTCTTTCTCCGCTTTCCAATAAGCGGACTGATGAATATGG
CGGTTCACCTGAAAACCGCTATCGTTTCTTACGCGAAATCATTGACTCGATAAATGAAGTTTGGAACGGACCGTTATTTG
TTCGTATTTCAGCAAATGATTATCACCCTGACGGGTTAACGGTTCAAGATTACGTTCAGTATACAAAATGGATGAAAGAA
CAAGGAGTAGATTTAATCGATTGTAGTTCTGGGGCTGTTGTACCTGCACGCATCGATGTTTATCCTGGATATCAAGTACA
ATACGCTAAACATATTAAAGAACATGCTAACATTGCAACTGGTGCTGTTGGATTGATTACGACCGGGGCACAAGCAGAGC
AAATTTTAAACAATAACGAAGCAGATTTAATTTTTATCGGACGTGAGTTACTTCGCAATCCTTACTTCCCAAGAATAGCC
GCCAATGAACTTGGCTTTGAGTTAGAAGAACCGCATCAATACGAGCGAGCGCCTGGGAAAATTAGTACAAATAAATAA

Upstream 100 bases:

>100_bases
GTAACACGAATAGACAAAATTTTTCGTATAAGCGTTTTATTAGTGAAAACAAAAAAGAGAATGATACAATATAAGAAAAT
TCAATCTAGGAGGCTATTGG

Downstream 100 bases:

>100_bases
AACCGAGAAGCTTTTCTTCTCGGTTTTATTTATTCTATCGTTGTAATTTCATTCGAATTGTAAATATGGATACCTGATTC
TTCTCGCAATGCAGTTATAT

Product: NADPH dehydrogenase NamA

Products: NA

Alternate protein names: Xenobiotic reductase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAVPFNETMKIPVEMSIHQIKNTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK

Sequences:

>Translated_345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAVPFNETMKIPVEMSIHQIKNTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK
>Mature_345_residues
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPSAVPFNETMKIPVEMSIHQIKNTILAFQQAAIRSKQAGFDV
IEIHGAHGYLINEFLSPLSNKRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPHQYERAPGKISTNK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily

Homologues:

Organism=Escherichia coli, GI1787939, Length=238, Percent_Identity=33.1932773109244, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789463, Length=315, Percent_Identity=29.8412698412698, Blast_Score=117, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17559802, Length=261, Percent_Identity=31.4176245210728, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17559804, Length=174, Percent_Identity=36.7816091954023, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=181, Percent_Identity=32.5966850828729, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=257, Percent_Identity=29.9610894941634, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=249, Percent_Identity=31.3253012048193, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=333, Percent_Identity=28.5285285285285, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=174, Percent_Identity=33.9080459770115, Blast_Score=98, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=223, Percent_Identity=33.1838565022422, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=220, Percent_Identity=33.1818181818182, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAMA_BACAA (C3P7Z9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866426.1
- ProteinModelPortal:   C3P7Z9
- SMR:   C3P7Z9
- EnsemblBacteria:   EBBACT00000126087
- GeneID:   7853353
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_2105
- GeneTree:   EBGT00050000002219
- ProtClustDB:   PRK13523
- HAMAP:   MF_01614
- InterPro:   IPR013785
- InterPro:   IPR001155
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00724 Oxidored_FMN

EC number: =1.6.99.1

Molecular weight: Translated: 38459; Mature: 38459

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: BINDING 28-28 BINDING 164-164 BINDING 167-167 BINDING 215-215 BINDING 308-308

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEA
CCCCCCCCEEEEEEEECCEEEECHHEECCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCHHHCCCC
AVPFNETMKIPVEMSIHQIKNTILAFQQAAIRSKQAGFDVIEIHGAHGYLINEFLSPLSN
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPHQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSELFSPYTIKDVTLKNRIVMSPMCMYSSENEDGQVTNFHLIHYGTRAAGQVGLVMIEA
CCCCCCCCEEEEEEEECCEEEECHHEECCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCHHHCCCC
AVPFNETMKIPVEMSIHQIKNTILAFQQAAIRSKQAGFDVIEIHGAHGYLINEFLSPLSN
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIDSINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPHQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA