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The map label for this gene is yjhT

Identifier: 30065435

GI number: 30065435

Start: 4377439

End: 4378653

Strand: Direct

Name: yjhT

Synonym: S4469

Alternate gene names: 30065435

Gene position: 4377439-4378653 (Clockwise)

Preceding gene: 30065434

Following gene: 30065436

Centisome position: 95.18

GC content: 43.62

Gene sequence:

>1215_bases
ATGACTACCTTGACCGCCAGGGTGTTTACAACGGCAGAGATAATTTATCGGAAAACAGTTATCGCATTGGTGTGTCATTT
AAACTGTAGTAGACAGGAGACAGTCACAATGAATAAAACTATAATGGCGCTTGCTATCATGATGGCTTCATTTGCCGCAA
ACGCGTCTGTATTACCGGAAACTCCTGTGCCATTTAAAAGTGGTACCGGAGCAATTGATAACGACACTGTCTACATTGGT
TTAGGTAGCGCAGGTACAGCATGGTACAAGCTAGATACACAGGCCAAAGATAAAAAATGGACTGCGTTAGCTGCATTCCC
TGGTGGACCGAGAGAGCAAGCAACCTCTGCATTTATTGATGGCAATCTGTATGTGTTTGGCGGCATTGGCAAAAACAGCG
AGGGATTGACTCAGGTATTTAATGACGTACACAAATACAACCCCAAAACCAATAGCTGGGTTAAATTGATGTCGCACGCG
CCGATGGGCATGGCGGGTCATGTGACTTTTGTACACAACGGCAAGGCTTATGTTACTGGCGGTGTTAACCAGAATATCTT
CAATGGCTATTTTGAAGATCTCAACGAGGCTGGAAAAGATTCAACCGCTATAGATAAAATCAACGCCCACTATTTTGACA
AAAAAGCAGAAGATTATTTCTTCAATAAGTTTCTGTTGTCTTTTGATCCCTCAACACAGCAATGGAGTTACGCTGGCGAA
TCGCCCTGGTACGGAACGGCTGGTGCGGCGGTTGTGAATAAAGGTGATAAAACCTGGCTTATTAATGGCGAAGCCAAACC
AGGATTGCGAACGGATGCCGTATTTGAACTTGATTTCACCGGTAATAATTTAAAATGGAATAAGCTTGATCCCGTCTCAT
CACCAGATGGCGTCGCTGGCGGTTTTGCGGGGATAAGCAATGATTCTCTTATATTTGCTGGAGGGGCCGGATTCAAAGGT
TCACGAGAAAATTACCAGAACGGTAAGAACTATGCGCATGAAGGCCTGAAAAAATCATATAGCACTGATATTCATCTTTG
GCATAACGGGAAATGGGATAAATCGGGTGAATTATCGCAAGGTCGGGCCTACGGAGTATCATTGCCCTGGAATAATAGTT
TATTAATTATTGGCGGTGAAACTGCAGGCGGCAAAGCGGTGACGGATTCAGTTTTAATTTCTGTGAAGGATAATAAAGTC
ACAGTACAAAACTAA

Upstream 100 bases:

>100_bases
CAGAATGATTATCGCTATGCAAACCACAAGAAATGGGCGACGGAAAATGCCTTTGTTCTACAATACCATATGACGCCCGA
TATTACGCCATACATAGAAT

Downstream 100 bases:

>100_bases
CGCTTCAGGGCCCCGGTAAAGGGGCCCTGCTATCAATTTGTCATTTGTATTACGCGAAAATTATATGAACGCAATAATAT
CACCCGATTATTACTATGTT

Product: N-acetylneuraminic acid mutarotase

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase 2; Neu5Ac mutarotase 2; Sialic acid epimerase 2 [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTTLTARVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTIMALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
LGSAGTAWYKLDTQAKDKKWTALAAFPGGPREQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHA
PMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGE
SPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAGGFAGISNDSLIFAGGAGFKG
SRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKV
TVQN

Sequences:

>Translated_404_residues
MTTLTARVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTIMALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
LGSAGTAWYKLDTQAKDKKWTALAAFPGGPREQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHA
PMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGE
SPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAGGFAGISNDSLIFAGGAGFKG
SRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKV
TVQN
>Mature_403_residues
TTLTARVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTIMALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIGL
GSAGTAWYKLDTQAKDKKWTALAAFPGGPREQATSAFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHAP
MGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGES
PWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAGGFAGISNDSLIFAGGAGFKGS
RENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKVT
VQN

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=368, Percent_Identity=98.9130434782609, Blast_Score=744, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 43713; Mature: 43582

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTARVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTIMALAIMMASFAANASVLPE
CCEEEEEHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCC
TPVPFKSGTGAIDNDTVYIGLGSAGTAWYKLDTQAKDKKWTALAAFPGGPREQATSAFID
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHCEEEEC
GNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTG
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEECCEEEEEC
GVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGE
CCCCHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCHHHHEEEEEEEECCCCCCCCCCCC
SPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAG
CCCCCCCCCEEEECCCEEEEEECCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCC
GFAGISNDSLIFAGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQ
CCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
GRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN
CCEEEEECCCCCEEEEEECCCCCCCEEECEEEEEEECCEEEECC
>Mature Secondary Structure 
TTLTARVFTTAEIIYRKTVIALVCHLNCSRQETVTMNKTIMALAIMMASFAANASVLPE
CEEEEEHHHHHHHHHHHHHHHHHEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCC
TPVPFKSGTGAIDNDTVYIGLGSAGTAWYKLDTQAKDKKWTALAAFPGGPREQATSAFID
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHCEEEEC
GNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTG
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEECCEEEEEC
GVNQNIFNGYFEDLNEAGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGE
CCCCHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCHHHHEEEEEEEECCCCCCCCCCCC
SPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLDPVSSPDGVAG
CCCCCCCCCEEEECCCEEEEEECCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCCCC
GFAGISNDSLIFAGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQ
CCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
GRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN
CCEEEEECCCCCEEEEEECCCCCCCEEECEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]