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The map label for this gene is dgoT

Identifier: 30065001

GI number: 30065001

Start: 3892275

End: 3893612

Strand: Reverse

Name: dgoT

Synonym: S3998

Alternate gene names: 30065001

Gene position: 3893612-3892275 (Counterclockwise)

Preceding gene: 30065002

Following gene: 30064999

Centisome position: 84.66

GC content: 53.06

Gene sequence:

>1338_bases
ATGGTGAGCGGCTTCGCTATGCCCAAAATCTGGAGAAAGCTCGCTATGGATATTCCCGTTAATGCAGCAAAGCCGGGGCG
TCGGCGTTATCTGACGCTGGTGATGATCTTTATTACGGTGGTCATTTGTTATGTTGACCGCGCTAACCTGGCCGTGGCTT
CCGCCCATATTCAGGAAGAGTTCGGCATTACGAAAGCGGAAATGGGCTATGTATTTTCGGCCTTCGCCTGGCTTTATACG
CTATGCCAGATCCCCGGCGGTTGGTTTTTAGATCGCGTAGGTTCTCGCGTGACTTATTTTATTGCGATATTTGGTTGGTC
AGTGGCGACTTTATTCCAAGGCTTTGCCACGGGATTAATGTCATTAATTGGTCTGCGTGCGATAACCGGTATTTTCGAAG
CGCCCGCTTTCCCGACCAATAACCGGATGGTGACCAGCTGGTTCCCGGAACATGAACGCGCTTCCGCCGTTGGTTTTTAT
ACGTCTGGTCAGTTTGTCGGTCTGGCGTTTTTGACTCCGCTGCTGATCTGGATTCAGGAGATGTTGAGCTGGCACTGGGT
GTTCATTGTCACTGGTGGTATCGGCATTATCTGGTCGCTGATTTGGTTTAAGGTTTATCAGCCGCCGCGCCTGACCAAAG
GTATCAGCAAAGCTGAACTGGATTACATTCGTGATGGCGGCGGTCTGGTGGATGGTGATGCGCCGGTGAAGAAAGAGGCG
CGTCAGCCGTTAACAGCCAAAGACTGGAAACTGGTGTTCCATCGTAAACTGATCGGCGTTTATCTTGGGCAATTTGCGGT
GGCTTCTGCACTGTGGTTTTTCTTAACCTGGTTCCCGAACTATTTAACCCAGGAAAAAGGAATCACGGCGCTGAAAGCAG
GCTTTATGACCACGGTGCCATTCCTCGCGGCGTTTGTCGGCGTCCTGCTCTCTGGCTGGGTCGCGGATCTGCTGGTACGT
AAGGGCTTTTCACTGGGCTTTGCGCGTAAAACGCCGATTATCTGCGGCTTGCTGATCTCCACCTGCATTATGGGCGCTAA
CTACACCAACGATCCGATGATGATTATGTGCCTGATGGCGCTGGCATTCTTCGGCAACGGTTTTGCTTCGATTACCTGGT
CGCTGGTCTCTTCTCTGGCACCGATGCGCCTGATTGGTTTAACCGGCGGCGTGTTTAACTTCGCCGGTGGTCTGGGCGGC
ATCACCGTTCCGCTGGTGGTGGGGTACCTGGCGCAGGGTTACGGTTTCGCGCCTGCACTGGTTTATATCTCCGCCGTCGC
GTTGATTGGCGCGCTCTCTTACATCCTGCTGGTGGGTGATGTGAAGCGCGTTGGATAA

Upstream 100 bases:

>100_bases
AAGATAACAGCGTAGCAGAGTGGTAATTCCTGCCACGTAAGCCCCTCATCGGGCACTAAAACAGCAATACAAAAATATAA
CCCTCTGTAAATTACAGGGC

Downstream 100 bases:

>100_bases
TCTTTCAACTGTGGAATATGCGCCACACCACTGCGCATAATCCACTTTCTTAAAGCCGGTGCGGTCAGGCATCGGCTTTT
TACTATCTTGCCGAAGAGTT

Product: D-galactonate transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYT
LCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEA
RQPLTAKDWKLVFHRKLIGVYLGQFAVASALWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVR
KGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGG
ITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG

Sequences:

>Translated_445_residues
MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYT
LCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEA
RQPLTAKDWKLVFHRKLIGVYLGQFAVASALWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVR
KGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGG
ITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG
>Mature_445_residues
MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYT
LCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEA
RQPLTAKDWKLVFHRKLIGVYLGQFAVASALWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVR
KGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGG
ITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG

Specific function: Intake of galactonate into the cell [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=412, Percent_Identity=24.2718446601942, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI6912666, Length=420, Percent_Identity=25.2380952380952, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI9945322, Length=410, Percent_Identity=25.1219512195122, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI21322234, Length=407, Percent_Identity=23.5872235872236, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI148743791, Length=389, Percent_Identity=26.9922879177378, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI9966811, Length=408, Percent_Identity=23.5294117647059, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI148728191, Length=309, Percent_Identity=27.5080906148867, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI223718438, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5031955, Length=264, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=99.7674418604651, Blast_Score=861, Evalue=0.0,
Organism=Escherichia coli, GI1789152, Length=435, Percent_Identity=42.5287356321839, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=40.9195402298851, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=29.1954022988506, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI2367193, Length=410, Percent_Identity=27.0731707317073, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788573, Length=437, Percent_Identity=23.5697940503432, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=21.7494089834515, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082404, Length=360, Percent_Identity=24.4444444444444, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=427, Percent_Identity=25.0585480093677, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=423, Percent_Identity=25.0591016548463, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71997452, Length=407, Percent_Identity=23.8329238329238, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=427, Percent_Identity=23.6533957845433, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=431, Percent_Identity=24.1299303944316, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=377, Percent_Identity=25.7294429708223, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=203, Percent_Identity=26.1083743842365, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=203, Percent_Identity=26.1083743842365, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=203, Percent_Identity=26.1083743842365, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=266, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=266, Percent_Identity=22.5563909774436, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=332, Percent_Identity=24.0963855421687, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=361, Percent_Identity=23.8227146814404, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193205400, Length=239, Percent_Identity=24.2677824267782, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550460, Length=318, Percent_Identity=25.1572327044025, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24648416, Length=409, Percent_Identity=25.1833740831296, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21356189, Length=409, Percent_Identity=25.1833740831296, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24655255, Length=278, Percent_Identity=25.5395683453237, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573299, Length=410, Percent_Identity=23.4146341463415, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24658658, Length=408, Percent_Identity=22.5490196078431, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20130135, Length=408, Percent_Identity=23.0392156862745, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24655271, Length=408, Percent_Identity=23.0392156862745, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20130167, Length=439, Percent_Identity=23.6902050113895, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI62484226, Length=424, Percent_Identity=23.8207547169811, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24639764, Length=334, Percent_Identity=23.6526946107784, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573708, Length=339, Percent_Identity=21.5339233038348, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573707, Length=339, Percent_Identity=21.5339233038348, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24658674, Length=410, Percent_Identity=23.4146341463415, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550495, Length=406, Percent_Identity=22.4137931034483, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654215, Length=441, Percent_Identity=24.0362811791383, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24653727, Length=387, Percent_Identity=25.3229974160207, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922400, Length=424, Percent_Identity=24.5283018867925, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=23.5142118863049, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583789, Length=380, Percent_Identity=22.1052631578947, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580790, Length=373, Percent_Identity=25.201072386059, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920686, Length=390, Percent_Identity=22.0512820512821, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584153, Length=300, Percent_Identity=21.6666666666667, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24658689, Length=410, Percent_Identity=22.4390243902439, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45552797, Length=410, Percent_Identity=22.4390243902439, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129235, Length=273, Percent_Identity=24.1758241758242, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550364, Length=220, Percent_Identity=22.7272727272727, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48764; Mature: 48764

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEE
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLM
HCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQE
HHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEA
HHHHEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHH
RQPLTAKDWKLVFHRKLIGVYLGQFAVASALWFFLTWFPNYLTQEKGITALKAGFMTTVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPAL
HHHHCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
VYISAVALIGALSYILLVGDVKRVG
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEE
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLM
HCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQE
HHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEA
HHHHEEEEEEECCHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHH
RQPLTAKDWKLVFHRKLIGVYLGQFAVASALWFFLTWFPNYLTQEKGITALKAGFMTTVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPAL
HHHHCCCHHHHHHHHHHHCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHH
VYISAVALIGALSYILLVGDVKRVG
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]