Click here to switch to the map view.

The map label for this gene is adiA

Identifier: 30064686

GI number: 30064686

Start: 3501868

End: 3504135

Strand: Reverse

Name: adiA

Synonym: S3624

Alternate gene names: 30064686

Gene position: 3504135-3501868 (Counterclockwise)

Preceding gene: 30064687

Following gene: 30064685

Centisome position: 76.19

GC content: 52.47

Gene sequence:

>2268_bases
ATGAAAGTATTAATTGTTGAAAGCGAGTTTCTCCATCAAGACACCTGGGTCGGTAACGCCGTTGAGCGTCTGGCAGATGC
TTTAAGCCAGCAAAATGTTACCGTGATTAAATCCACCTCCTTTGATGATGGTTTTGCCATTCTCTCTTCAAACGAAGCCA
TTGACTGCCTGATGTTCAGCTATCAAATGGAGCATCCGGACGAACATCAAAACGTCAGACAATTGATCGGTAAGCTTCAT
GAGCGCCAACAAAACGTGCCGGTCTTCCTGTTGGGCGATCGGGAAAAAGCCCTCGCCGCAATGGACCGGGATCTGCTGGA
GCTTGTCGATGAATTCGCCTGGATTCTGGAAGATACCGCCGACTTTATCGCCGGACGCGCCGTTGCCGCGATGACCCGCT
ACCGCCAGCAGCTGTTGCCGCCACTGTTCAGCGCGCTGATGAAATATAGTGACATCCATGAATATTCCTGGGCAGCGCCA
GGCCACCAGGGCGGCGTTGGTTTTACCAAAACACCCGCCGGACGTTTCTACCATGACTACTATGGTGAAAATCTGTTCCG
TACCGACATGGGCATCGAACGAACTTCCCTCGGTTCTTTGCTTGACCATACTGGCGCATTTGGCGAAAGCGAAAAATATG
CCGCACGCGTATTTGGTGCCGATCGCTCCTGGTCGGTAGTCGTCGGTACTTCCGGCTCTAACCGCACCATCATGCAGGCT
TGCATGACCGATAACGATGTCGTGGTCGTTGACCGTAACTGCCATAAATCCATCGAACAAGGTTTGATGCTGACAGGCGC
GAAACCGGTCTATATGGTGCCAAGCCGCAACCGCTACGGCATTATCGGGCCAATCTATCCGCAGGAAATGCAACCTGAAA
CCTTGCAAAAGAAAATCAGTGAAAGCCCGCTGACCAAAGACAAAGCCGGGCAAAAACCGTCTTACTGCGTGGTAACCAAC
TGCACCTATGACGGCGTGTGTTATAACGCTAAAGAAGCGCAGGATCTGCTGGAAAAAACCTCCGATCGTCTGCACTTTGA
CGAAGCCTGGTACGGCTATGCACGTTTCAACCCGATCTATGCCGATCACTATGCCATGCGCGGCGAACCTGGCGATCACA
ACGGTCCTACCGTTTTCGCCACCCACTCCATCCACAAACTGCTGAATGCGCTGTCACAGGCTTCTTATATTCATGTACGT
GAAGGTCGTGGGGCGATTAACTTCTCCCGCTTCAACCAGGCCTACATGATGCATGCCACCACCTCCCCGCTGTATGCCAT
CTGCGCATCCAACGACGTGGCGGTGTCGATGATGGACGGCAACAGCGGCCTGTCACTGACACAGGAAGTGATTGACGAAG
CGGTTGATTTCCGTCAGGCGATGGCGCGGCTATATAAAGAGTTCACCGCTGACGGTAGCTGGTTCTTCAAACCGTGGAAC
AAAGAAGTCGTCACCGACCCACAAACCGGCAAAACCTATGACTTTGCTGACGCACCAACCAAACTGCTGACCACCGTTCA
GGACTGCTGGGTAATGCATCCGGGCGAAAGCTGGCACGGCTTCAAAGATATTCCGGATAACTGGAGTATGCTCGACCCAA
TTAAAGTCAGCATCCTTGCTCCGGGAATGGGTGAAGATGGTGAACTGGAAGAAACCGGTGTTCCGGCGGCGCTGGTCACT
GCCTGGCTTGGTCGCCACGGCATTGTGCCTACCCGCACCACTGACTTCCAAATTATGTTCCTGTTCTCTATGGGCGTAAC
CCGTGGGAAATGGGGGACTCTGGTTAACACCCTTTGCTCCTTCAAACACCACTATGACGCCAACACACCGCTGGCGCAGG
TGATGCCGGAACTTGTTGAACAATATCCTGACACTTACGCGAACATGGGGATTCACGATCTGGGTGACACCATGTTTGCC
TGGCTGAAAGAAAACAACCCTGGCGCACGGTTGAACGAAGCCTATTCCGGCCTGCCGGTGGCGGAAATCACCCCGCGTGA
AGCGTACAACGCGATTGTCGACAACAATGTCGAACTGGTATCCATTGAAAATCTGCCAGGACGCATCGCGGCAAACTCAG
TTATCCCGTATCCGCCAGGAATCCCGATGCTGCTGTCTGGTGAAAACTTCGGCGATAAAAACAGTCCGCAAGTAAGTTAT
TTACGCTCGCTGCAATCCTGGGACCACCATTTCCCTAGATTTGAACACGAAACTGAAGGGACTGAAATTATTGACGGTAT
TTACCACGTTATGTGCGTGAAAGCGTAA

Upstream 100 bases:

>100_bases
AATATTTCAAAAATGTTTGTTTTTCACGCGCTTTACAGCCCGAAAAGGCCGGAAGATACTTGCCCGCAACGAAGATTCCT
TCATAACCGGGTAAGCAATG

Downstream 100 bases:

>100_bases
CCACTATTCCGCTGAAGGCGTAATTGTTTAAATAACATTACGCCGCCTGGCCTTAGGCCTTTTGAGTATGGCAACGTTTT
CATAAAAATTGCTGCAAACA

Product: biodegradative arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLH
ERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQA
CMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTN
CTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSIHKLLNALSQASYIHVR
EGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWN
KEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVT
AWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKHHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFA
WLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSY
LRSLQSWDHHFPRFEHETEGTEIIDGIYHVMCVKA

Sequences:

>Translated_755_residues
MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLH
ERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQA
CMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTN
CTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSIHKLLNALSQASYIHVR
EGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWN
KEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVT
AWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKHHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFA
WLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSY
LRSLQSWDHHFPRFEHETEGTEIIDGIYHVMCVKA
>Mature_755_residues
MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLH
ERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQA
CMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTN
CTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSIHKLLNALSQASYIHVR
EGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWN
KEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVT
AWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKHHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFA
WLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSY
LRSLQSWDHHFPRFEHETEGTEIIDGIYHVMCVKA

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=755, Percent_Identity=99.4701986754967, Blast_Score=1581, Evalue=0.0,
Organism=Escherichia coli, GI1790573, Length=740, Percent_Identity=35.5405405405405, Blast_Score=470, Evalue=1e-133,
Organism=Escherichia coli, GI1786384, Length=735, Percent_Identity=34.5578231292517, Blast_Score=451, Evalue=1e-127,
Organism=Escherichia coli, GI87082193, Length=636, Percent_Identity=33.3333333333333, Blast_Score=357, Evalue=1e-99,
Organism=Escherichia coli, GI1786909, Length=678, Percent_Identity=31.4159292035398, Blast_Score=335, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 84532; Mature: 84532

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCEEEEEEE
YQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTA
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
YGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQA
HCCCEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCEEEEECCCCCHHHHHH
CMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKIS
HCCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHH
ESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIY
CCCCCCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCCEECHHHCCCEECCCEE
ADHYAMRGEPGDHNGPTVFATHSIHKLLNALSQASYIHVREGRGAINFSRFNQAYMMHAT
ECCCEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEEECCCCCEEHHHCCCEEEEEEC
TSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWN
CCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
KEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILA
CCEECCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEEEC
PGMGEDGELEETGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCS
CCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHH
FKHHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPV
HHHCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCC
AEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSY
CCCCCHHHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCHHHH
LRSLQSWDHHFPRFEHETEGTEIIDGIYHVMCVKA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECC
>Mature Secondary Structure
MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFS
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCEEEEEEE
YQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTA
EECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAPGHQGGVGFTKTPAGRFYHDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
YGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQA
HCCCEEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCEEEEECCCCCHHHHHH
CMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKIS
HCCCCCEEEECCCHHHHHHCCEEEECCCCEEECCCCCCCEEECCCCCCCCCHHHHHHHHH
ESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIY
CCCCCCCCCCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHCCCEECHHHCCCEECCCEE
ADHYAMRGEPGDHNGPTVFATHSIHKLLNALSQASYIHVREGRGAINFSRFNQAYMMHAT
ECCCEECCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEEECCCCCEEHHHCCCEEEEEEC
TSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFTADGSWFFKPWN
CCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
KEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILA
CCEECCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCEEEEEEC
PGMGEDGELEETGVPAALVTAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCS
CCCCCCCCCHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHH
FKHHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPV
HHHCCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCC
AEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSY
CCCCCHHHHHHHHCCCEEEEEECCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCHHHH
LRSLQSWDHHFPRFEHETEGTEIIDGIYHVMCVKA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]