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The map label for this gene is mreD

Identifier: 30064580

GI number: 30064580

Start: 3376041

End: 3376529

Strand: Reverse

Name: mreD

Synonym: S3504

Alternate gene names: 30064580

Gene position: 3376529-3376041 (Counterclockwise)

Preceding gene: 30064581

Following gene: 30064579

Centisome position: 73.41

GC content: 50.92

Gene sequence:

>489_bases
GTGGCGAGCTATCGTAGCCAGGGACGCTGGGTAATCTGGCTCTCTTTCCTCATTGCGCTGTTGCTGCAAATCATGCCCTG
GCCGGATAACCTGATTGTTTTCCGGCCAAACTGGGTGTTACTTATCTTGTTGTATTGGATCCTGGCCTTGCCCCATCGCG
TAAATGTGGGCACAGGTTTTGTGATGGGTGCCATACTGGATCTGATCAGCGGCTCGATGCTTGGCGTACGCGTATTGGCG
ATGAGCATCATTGCTTACCTGGTGGCGCTGAAATACCAGCTTTTCCGCAACCTCGCATTATGGCAGCAGGCGCTGGTCGT
CATGTTGCTTTCGCTGGTGGTGGATATTATTGTTTTCTGGGCAGAGTTTTTAGTGATTAACGTCTCTTTCAGACCGGAAG
TGTTCTGGAGTAGTGTAGTCAATGGGGTGCTCTGGCCGTGGATTTTCTTGCTGATGCGTAAAGTCCGTCAGCAGTTTGCA
GTGCAATAA

Upstream 100 bases:

>100_bases
CTGTTGCGCCGACACAGCCCGCTGCTAATCGCTCTCCACAAAGGGCTACGCCGCCGCAAAGTGGTGCTCAACCGCCTGCG
CGTGCGCCGGGAGGGCAATA

Downstream 100 bases:

>100_bases
AGGTTTCTATGACTTCTCTGTATTTAGCTTCCGGTTCTCCGCGTCGTCAGGAGTTACTTGCGCAACTTGGCGTGACCTTT
GAACGTATTGTTACGGGCAT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSMLGVRVLA
MSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ

Sequences:

>Translated_162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSMLGVRVLA
MSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ
>Mature_161_residues
ASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSMLGVRVLAM
SIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAV
Q

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=162, Percent_Identity=99.3827160493827, Blast_Score=308, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18818; Mature: 18687

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSMLGVRVLAMSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSMLGVRVLAMSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]