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The map label for this gene is yhcS

Identifier: 30064575

GI number: 30064575

Start: 3367472

End: 3368383

Strand: Direct

Name: yhcS

Synonym: S3498

Alternate gene names: 30064575

Gene position: 3367472-3368383 (Clockwise)

Preceding gene: 30064570

Following gene: 30064584

Centisome position: 73.22

GC content: 53.07

Gene sequence:

>912_bases
ATGTCGGTGTTTGCCAAAGTAGTTGAATTTGGCTCTTTTACCGCCGCCGCCAGACAGCTACAGATGAGCGTTTCGTCCAT
CAGTCAGACGGTGTCAAAACTGGAAGATGAGTTGCAGGTAAAGCTGTTAAACCGTAGCACACGCAGCATTGGCCTGACCG
AAGCCGGTAGAATTTACTACCAGGGCTGCCGTCGTATGCTTCATGAAGTGCAGGATGTTCATGAGCAACTGTATGCCTTC
AATAACACCCCCATCGGGACGCTACGCATTGGCTGTTCTTCAACTATGGCACAAAATGTTCTCGCCGGGCTGACAGCCAA
AATGCTGAAAGAATACCCAGGTTTGAGCGCCAATCTGGTTACCGGAATTCCAGCCCCCGACCTGATTGCCGACGGTCTGG
ATGTGGTGATCCGCGTCGGCGCGTTGCAGGATTCCAGCCTGTTTTCCCGCCGTCTTGGCGCGATGCCAATGGTGGTGTGC
GCCGCGAAAAGCTATCTCACACAATACGGCATACCGGAAAAACCCGCCGATTTAAGTAGCCATTCATGGCTTGAATACAG
CGTGCGGCCCGACAATGAATTTGAACTGATTGCACCGGAAGGGATCTCGACTCGCCTGATCCCGCAAGGGAGATTTGTGA
CTAATGATCCGATGACGCTGGTGCGCTGGCTAACGGCGGGTGCCGGGATCGCCTACGTGCCGCTGATGTGGGTGATCAAC
GAGATCAATCGTGGGGAGCTGGAGATCCTGCTGCCGCGTTATCAGTCAGATCCACGCCCGGTTTATGCGTTATATACCGA
AAAAGATAAGCTGCCGCTGAAGGTACAGGTCGTGATCAACTCGCTGACGGATTATTTTGTTGAGGTCGGTAAATTGTTTC
AGGAGATGCACGGGCGCGGGAAAGAGAAGTAA

Upstream 100 bases:

>100_bases
ATTGATATTTAATATATTAGCGTAACTGTTATGCTGTTATCTATATTATGTGATCTAAATCACTTTTAAGTCAGAGTGAA
TAATGGAACGACTAAAACGC

Downstream 100 bases:

>100_bases
TTCATATTGTACTGTTACGTTCTACAAACCTGTGCCAACGGGTTCCCCTCACCCTAACCCCAGAGGAGCGAGGGGACCGT
TCGTGCACGTAGAAAGATTA

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAF
NNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSANLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVC
AAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVIN
EINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK

Sequences:

>Translated_303_residues
MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAF
NNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSANLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVC
AAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVIN
EINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
>Mature_302_residues
SVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFN
NTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSANLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCA
AKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINE
INRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=303, Percent_Identity=99.6699669966997, Blast_Score=625, Evalue=1e-180,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=31.0580204778157, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=31.8181818181818, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=27.2425249169435, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=29.6551724137931, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787589, Length=266, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=26.7361111111111, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=33.6134453781513, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=143, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=23.7704918032787, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33674; Mature: 33543

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYY
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHH
QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSANLV
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
TGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSS
ECCCCHHHHHCCHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
HSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVIN
CCEEEEEECCCCCEEEECCCCCCEEECCCCCEECCCHHHHHHHHHHCCCHHHHHHHHHHH
EINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRG
HCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCC
KEK
CCC
>Mature Secondary Structure 
SVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHH
QGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSANLV
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
TGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSS
ECCCCHHHHHCCHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
HSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVIN
CCEEEEEECCCCCEEEECCCCCCEEECCCCCEECCCHHHHHHHHHHCCCHHHHHHHHHHH
EINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRG
HCCCCCEEEEECCCCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCC
KEK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]