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The map label for this gene is ygiP

Identifier: 30064408

GI number: 30064408

Start: 3183024

End: 3184025

Strand: Reverse

Name: ygiP

Synonym: S3306

Alternate gene names: 30064408

Gene position: 3184025-3183024 (Counterclockwise)

Preceding gene: 30064412

Following gene: 30064406

Centisome position: 69.23

GC content: 49.1

Gene sequence:

>1002_bases
ATGCTGAATAGCTGGCCTTTAGCCAAAGACTTGCAGGTACTGGTAGAAATCGTCCACAGCGGGAGTTTTAGTGCTGCAGC
GGCGACGCTTGGGCAAACGCCTGCATTTGTCACCAAGCGGATCCAAATCCTTGAAAATACGCTGGCAACAACGCTGCTGA
ACCGCTCCGCTCGCGGCGTGGCGCTGACTGAAAGTGGCCAACGTTGTTACGAACATGCGCTGGAAATCCTCACCCAATAT
CAGCGACTGGTCGATGACGTCACGCAAATCAAAACGCGCCCGGAGGGGATGATTCGTATTGGTTGCAGTTTTGGTTTTGG
GCGCAGCCATATTGCGCCAGCCATTACCGAACTTATGCGCAATTATCCTGAGTTACAGGTGCATTTTGAATTGTTCGATC
GGCAAATTGATTTAGTGCAGGATAATATTGATCTGGATATTCGTATTAATGACGAAATTCCTGATTATTATATTGCGCAT
CTGTTAACGAAAAATAAAAGAATATTATGCGCAGCACCTGAGTATCTGCAAAAATATCCGCAGCCACAATCATTACAGGA
ATTAAGTCGTCATGACTGTCTGGTGACCAAAGAGCGCGATATGACCCACGGAATATGGGAGTTGGGGAACGGTCAGGAGA
AAAAATCGGTGAAGGTTAGCGGGCATCTTTCCTCCAATAGCGGCGAGATAGTGTTGCAATGGGCGCTGGAGGGCAAAGGG
ATTATGCTGCGTTCCGAGTGGGATGTGTTGCCGTTTCTGGAGAGTGGCAAACTGGTGCAAGTATTGCCGGAGTATGCACA
AAGCGCCAATATCTGGGCTGTTTACCGGGAGCTGCTCTATCGCAGCATGAAATTCGTGTCTGCGCGGAATTTCTGGCGGC
ATGGTGCCAGCAACGGCTGGGCAAGCCCGATGAAGGCTATCAGGTCATGTAGATCCACCAGAAATCACTCGGGATCCTTT
TCGCGCTTTCTTTTGAATTTCGTCCAGATTTTTGTCTCCTGA

Upstream 100 bases:

>100_bases
GTGAATCAACGCGAAAATAAGAATGAATATTGCGCCAGAGCAGGGAATGGCAATGTTTTGCGAAATACACTGCGCTTATC
ACAACTGCGGATAATTAACG

Downstream 100 bases:

>100_bases
CGACGCCACAGACGCTGGATGTTGTCATGATGACGCAGCAGGATCAGGCAAGAGAGCATCGAAACCGGGAAGGTGAATTG
TGGCTTAAACCACCAGACAT

Product: transcriptional activator TtdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQY
QRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYRELLYRSMKFVSARNFWRHGASNGWASPMKAIRSCRSTRNHSGSF
SRFLLNFVQIFVS

Sequences:

>Translated_333_residues
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQY
QRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYRELLYRSMKFVSARNFWRHGASNGWASPMKAIRSCRSTRNHSGSF
SRFLLNFVQIFVS
>Mature_333_residues
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQY
QRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYRELLYRSMKFVSARNFWRHGASNGWASPMKAIRSCRSTRNHSGSF
SRFLLNFVQIFVS

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=97.5945017182131, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=47.945205479452, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1786401, Length=259, Percent_Identity=29.3436293436293, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI145693193, Length=281, Percent_Identity=30.6049822064057, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1789639, Length=270, Percent_Identity=27.037037037037, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787128, Length=267, Percent_Identity=24.3445692883895, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787589, Length=272, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786448, Length=240, Percent_Identity=24.1666666666667, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=166, Percent_Identity=28.3132530120482, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788706, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789173, Length=266, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37910; Mature: 37910

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGV
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
NYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYP
CCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECHHHHHHCC
QPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
CCHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCE
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYRELLYRSMKFVSARNFWRHGASNGW
EEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASPMKAIRSCRSTRNHSGSFSRFLLNFVQIFVS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGV
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
ALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHH
NYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYP
CCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECHHHHHHCC
QPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
CCHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCE
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYRELLYRSMKFVSARNFWRHGASNGW
EEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASPMKAIRSCRSTRNHSGSFSRFLLNFVQIFVS
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]