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The map label for this gene is mdaB

Identifier: 30064378

GI number: 30064378

Start: 3154329

End: 3154910

Strand: Direct

Name: mdaB

Synonym: S3273

Alternate gene names: 30064378

Gene position: 3154329-3154910 (Clockwise)

Preceding gene: 30064376

Following gene: 30064379

Centisome position: 68.58

GC content: 49.66

Gene sequence:

>582_bases
ATGAGCAACATCCTGATTATCAACGGCGCGAAAAAATTCGCCCACTCCAATGGTCAACTGAACGACACCCTGACCGAAGT
CGCGGATGGCACACTGCGCGACCTCGGGCATGATGTCCGCATCGTTCGCGCCGACAGCGACTACAATGTCAAAGCGGAAG
TACAAAACTTTCTCTGGGCTGATGTGGTGATCTGGCAGATGCCAGGCTGGTGGATGGGCGCGCCGTGGACAGTGAAAAAA
TATATTGATGATGTATTCACCGAAGGTCACGGGACTCTGTATGCCAGCGATGGTCGTACCCGCAAAGATCCGTCGAAAAA
ATACGGTTCCGGCAGCCTGGTACAGGACAAAAAATATATGCTTTCTCTAACCTGGAACGCACCAATGGAAGCCTTCACCG
AAAAAGATCAGTTCTTCCACGGCGTTGGCGTTGACGGTGTGTATCTGCCGTTCCATAAAGCAAACCAATTCCTCGGTATG
GAACCGCTGCCGACATTTATCGCTAATGACGTGATAAAAATGCCTGATGTTCCCCGCTATACTGAAGAATATCGCAAGCA
TCTTGTGGAAATTTTTGGTTAA

Upstream 100 bases:

>100_bases
TTTTGCTAAATTCGCAAAAGACTTTGCACATTTTGCTAATTTCACAGTACCGCTCTGTGACGTACTATAGTCGACAAACG
TCTCACCTTGAGATTAAAAA

Downstream 100 bases:

>100_bases
CTAGAGCTCAGGCTTTAGAAGGAGTTAACCATGCTTACCGTAATCGCAGAAATCCGTACTCGTCCTGGTCAACATCACCG
TCAGGCGGTATTGGATCAGT

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWADVVIWQMPGWWMGAPWTVKK
YIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG

Sequences:

>Translated_193_residues
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWADVVIWQMPGWWMGAPWTVKK
YIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG
>Mature_192_residues
SNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKY
IDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGME
PLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=193, Percent_Identity=98.4455958549223, Blast_Score=396, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 21978; Mature: 21847

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWA
CCCEEEEECCHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
DVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYM
HEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEECCEEE
LSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRY
EEEEECCCHHHHHHHHHHEECCCCCCEEECHHHCCCCCCCCCCHHHHHCCCCCCCCCCCH
TEEYRKHLVEIFG
HHHHHHHHHHHCC
>Mature Secondary Structure 
SNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWA
CCEEEEECCHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
DVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYM
HEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCEEECCEEE
LSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRY
EEEEECCCHHHHHHHHHHEECCCCCCEEECHHHCCCCCCCCCCHHHHHCCCCCCCCCCCH
TEEYRKHLVEIFG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]