BacMap

Definition	Shigella flexneri 2a str. 2457T, complete genome.
Accession	NC_004741
Length	4,599,354

Click here to switch to the map view.

The map label for this gene is yghA

Identifier: 30064357

GI number: 30064357

Start: 3133766

End: 3134650

Strand: Direct

Name: yghA

Synonym: S3251

Alternate gene names: 30064357

Gene position: 3133766-3134650 (Clockwise)

Preceding gene: 30064355

Following gene: 30064358

Centisome position: 68.13

GC content: 54.58

Gene sequence:

>885_bases
ATGTCTCATTTAAAAGACCCGACCACGCAGTATTACACTGGTGAATATCCCAAACAGAAACAACCGACGCCAGGCATCCA
GGCGAAGATGACACCGATACCGGATTGCGGCGAGAAAACCTATGTTGGTAGCGGTCGCCTGAAAGATCGTAAAGCACTGG
TGACAGGGGGCGATTCCGGAATAGGTCGCGCTGCCGCCATCGCTTACGCGCGTGAAGGGGCTGACGTGGCGATCAGTTAT
CTTCCCGTGGAAGAAGAAGACGCTCAGGATGTGAAAAAGATCATTGAAGAATGCGGACGCAAAGCCGTTCTGCTGCCAGG
CGATTTAAGCGATGAGAAATTCGCCCGTTCGCTGGTTCACGAAGCGCACAAGGCGTTAGGCGGGCTGGATATTATGGCGC
TGGTCGCCGGGAAACAGGTTGCCATTCCGGATATTGCAGACCTCACCAGCGAACAGTTTCAAAAGACCTTTGCCATTAAC
GTTTTCGCGCTGTTCTGGCTAACCCAGGAAGCGATCCCCCTGCTACCGAAAGGTGCAAGTGTCATCACCACTTCGTCAAT
CCAGGCATACCAGCCAAGTCCGCATTTACTGGACTATGCGGCTACGAAGGCGGCGATTCTGAACTACAGCCGTGGCCTGG
CAAAACAGGTCGCGGAGAAAGGTATTCGGGTGAATATTGTCGCGCCAGGCCCTATCTGGACGGCACTGCAAATTTCCGGC
GGACAAACGCAGGATAAGATCCCGCAGTTTGGTCAGAAAACGCCGATGAAGCGTGCGGGGCAACCGGCGGAACTGGCCCC
TGTATATGTTTATCTGGCAAGTCAGGAGTCGAGCTACGTCACCGCAGAAGTGCACGGCGTGTGCGGCGGCGAGCATTTAG
GTTAA

Upstream 100 bases:

>100_bases
TGTCGCATAATTCTGAGGTTTAGGGATCTTCCTGGTTCCCTTATCAACGCATCGAGAGCGTCTACCCTTAAAGGACGTTG
AACCTGAAGGGAGAAAAACG

Downstream 100 bases:

>100_bases
AAAAATGCCCGGTTGTGAAAAGCAACCGGGCATCATTGTGAATTCACTCTTACCTGATGTGGCGAAAACGCCTTATCCGC
CTACAAACGCATGAAGATTC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPIPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY
LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
VFALFWLTQEAIPLLPKGASVITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG

Sequences:

>Translated_294_residues
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPIPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY
LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
VFALFWLTQEAIPLLPKGASVITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
>Mature_293_residues
SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPIPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYL
PVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINV
FALFWLTQEAIPLLPKGASVITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGG
QTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.5301204819277, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=26.7175572519084, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=27.3809523809524, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=30.3030303030303, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=28.8, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.9896907216495, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=32.258064516129, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=27.6679841897233, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=262, Percent_Identity=28.2442748091603, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI32455239, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI5031765, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=25.668449197861, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=27.710843373494, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789378, Length=294, Percent_Identity=98.9795918367347, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.9593495934959, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=30.8943089430894, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=32.5301204819277, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.4615384615385, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.3092369477912, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=27.6515151515151, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=27.2357723577236, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=26.2096774193548, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=32.6359832635983, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.6747967479675, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=29.8804780876494, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.2267657992565, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.9212598425197, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=28.4615384615385, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.5171102661597, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=29.2592592592593, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=28.8256227758007, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=30.0751879699248, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.8352059925094, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=30.241935483871, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.0754716981132, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.1904761904762, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=252, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=30.078125, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=28.3018867924528, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.4393939393939, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=27.1317829457364, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.3233082706767, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=27.3809523809524, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=28.8888888888889, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.4339622641509, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=271, Percent_Identity=28.0442804428044, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=30.3643724696356, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.0916334661355, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=24.390243902439, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.2945736434109, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.9236947791165, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=29.4820717131474, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=30.2788844621514, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.8804780876494, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=28.968253968254, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.6119402985075, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=35.5932203389831, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=236, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=28.2296650717703, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31488; Mature: 31357

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPIPDCGEKTYVGSGRLKDRKALVTGGDSG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC
IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS
HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPIPDCGEKTYVGSGRLKDRKALVTGGDSG
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC
IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH
EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS
HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC
GQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]