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The map label for this gene is glmU [H]

Identifier: 30064236

GI number: 30064236

Start: 3000407

End: 3000676

Strand: Direct

Name: glmU [H]

Synonym: S3113

Alternate gene names: 30064236

Gene position: 3000407-3000676 (Clockwise)

Preceding gene: 161486444

Following gene: 30064237

Centisome position: 65.24

GC content: 54.81

Gene sequence:

>270_bases
TTGCGCTATGCCGGGCAAGAAGGCACCACGCTCCTGAACGGTACATTCGAAGTGATCTCACTAAACGGCACGCTGGAACA
GAGTGGTGAGCATCTTCATCTCTGCGTTTCCGATCCACACGGCACGATGCTTGGCGGTCATATGATGCCCGGCTGTACCG
TGCGGACCACGCTTGAACTGGTGATCGGTAGCCTTGAGGAACTGGCGTTTAGCCGCCAACCTTGCGCGCTTTCTGGTTAC
GACGAGTTGCATATTTCCCCCGTTAAATAA

Upstream 100 bases:

>100_bases
CGGGCAGGAAGTTTTTTCCCAGCTACACGCTTTTGCACAGCAACATCAACTTCATGCCGCCTAGATTGCAGGCTGTACCG
GTAGCCTGACTGACGTCGCC

Downstream 100 bases:

>100_bases
CTACTTTCAAAGAGGTTTTCTTATGGCGCGTAGCCACTTTTCCAGTCAGGCACTGGTGTTGATCGTTATATCTATCGCCA
TCAATATGATCGGCGGGCAA

Product: putative DNA-binding protein

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGSLEELAFSRQPCALSGY
DELHISPVK

Sequences:

>Translated_89_residues
MRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGSLEELAFSRQPCALSGY
DELHISPVK
>Mature_89_residues
MRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGSLEELAFSRQPCALSGY
DELHISPVK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1661

COG function: function code R; Predicted DNA-binding protein with PD1-like DNA-binding motif

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005175
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF03479 DUF296; PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 9585; Mature: 9585

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLEL
CCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHH
VIGSLEELAFSRQPCALSGYDELHISPVK
HHCCHHHHHCCCCCCEECCCCCEEEEECC
>Mature Secondary Structure
MRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLEL
CCCCCCCCCEEECCEEEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHH
VIGSLEELAFSRQPCALSGYDELHISPVK
HHCCHHHHHCCCCCCEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA