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The map label for this gene is ygfU

Identifier: 30064200

GI number: 30064200

Start: 2957303

End: 2958820

Strand: Direct

Name: ygfU

Synonym: S3073

Alternate gene names: 30064200

Gene position: 2957303-2958820 (Clockwise)

Preceding gene: 30064199

Following gene: 30064201

Centisome position: 64.3

GC content: 48.55

Gene sequence:

>1518_bases
ATGTGTTTAGACAGTTTCATTAACGTAAACGGTTGCTTTTTATTCTGGCGGGCGAAAGGAGAAACACTGATGAGCGCCAT
AGATTCCCAACTTCCCTCATCTTCTGGGCAAGACCGCCCAACTGATGAGGTTGACCGCATATTATCACCAGGAAAGCTGA
TCATACTCGGTCTGCAACACGTCCTTGTCATGTACGCAGGTGCAGTCGCTGTTCCTCTTATGATTGGTGACCGACTGGGC
CTCTCAAAAGATGCTATTGCGATGCTCATTAGCTCGGATCTCTTTTGCTGCGGGATCGTCACATTATTGCAATGTATCGG
TATCGGCCGCTTTATGGGGATCCGCCTGCCGGTGATTATGTCGGTGACCTTTGCTGCTGTAACACCAATGATAGCCATTG
GGATGAACCCGGATATCGGCCTGCTGGGGATATTTGGTGCCACTATCGCCGCGGGTTTTATCACCACATTATTAGCGCCA
CTTATTGGTCGCTTGATGCCTTTATTCCCGCCACTGGTTACCGGTGTGGTTATTACTTCTATTGGGCTTAGCATCATTCA
GGTGGGTATTGACTGGGCCGCTGGAGGTAAAGGGAATCCGCAATATGGTAATCCCGTTTATTTAGGTATCTCCTTTGCCG
TCTTAATTTTTATCTTGCTCATTACTCGCTATGCGAAAGGATTTATGTCCAACGTCGCCGTATTACTGGGGATTGTATTT
GGCTTTTTACTTTCGTGGATGATGAATGAAGTCAATTTATCCGGGCTACATGATGCCTCGTGGTTTGCGATTGTCACCCC
GATGTCGTTTGGTATGCCGATTTTCGATCCCGTTTCCATTCTGACCATGACTGCCGTGTTAATCATCGTGTTTATCGAGT
CGATGGGGATGTTCCTGGCACTGGGTGAAATAGTCGGTCGTAAACTCTCTTCACACGATATTATTTGCGGGCTGCGTGTC
GATGGCGTAGGGACAATGATAGGCGGCACGTTTAACAGCTTCCCCCACACGTCATTTTCTCAAAACGTTGGCCTGGTTAG
CGTGATGCGCGTTCATAGCCGCTGGGTGTGTATTTCTTCGGGAATTATATTAATCCTGTTTGGCATGGTGCCAAAAATGG
CGGTGCTGGTAGCCTCCATTCCGCAATTTGTGCTGGGCGGCGCTGGTCTAGTGATGTTCGGCATGGTACTGGCGACAGGG
ATTCGAATTCTGTCGCGCTGTAACTACACCACCAACCGTTACAACCTCTATATTGTGGCGATCAGTCTCGGCGTTGGCAT
GACTCCGACGCTCTCTCACGATTTCTTTTCTAAGTTACCGGCCGTACTGCAACCGCTGCTACATAGCGGCATTATGCTCG
CAACCCTTAGCGCCGTTGTGCTGAACGTCTTCTTTAATGGCTATCAGCATCATGCTGACCTGGTGAAGGAATCCGTCTCT
GATAAAGATTTAGAAGTCAGGACAGTACGTATGTGGCTTCTGATGCGCAAGCTGAAGAAAAATGAGCATGGAGAATAA

Upstream 100 bases:

>100_bases
TTTCTCTTGTCATTTTCGTGGTTTAAGCACGATTATGTGATTGCCTCCGCAATTCCTGTCTCTAACTCCCCTTCCTCGCA
AAAACTGGCACTCCACGAGC

Downstream 100 bases:

>100_bases
TATGAATTTTTTAATGCGCGCTATATTCAGTCTGTTGTTGCTTTTTACTCTCTCTATTCCTGTCATTTCTGACTGTGTTG
CAATGGCCATTGAAAGTCGC

Product: putative permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MCLDSFINVNGCFLFWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLG
LSKDAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAP
LIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVF
GFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIICGLRV
DGVGTMIGGTFNSFPHTSFSQNVGLVSVMRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATG
IRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVS
DKDLEVRTVRMWLLMRKLKKNEHGE

Sequences:

>Translated_505_residues
MCLDSFINVNGCFLFWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLG
LSKDAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAP
LIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVF
GFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIICGLRV
DGVGTMIGGTFNSFPHTSFSQNVGLVSVMRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATG
IRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVS
DKDLEVRTVRMWLLMRKLKKNEHGE
>Mature_505_residues
MCLDSFINVNGCFLFWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAGAVAVPLMIGDRLG
LSKDAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAP
LIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVF
GFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLALGEIVGRKLSSHDIICGLRV
DGVGTMIGGTFNSFPHTSFSQNVGLVSVMRVHSRWVCISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATG
IRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHADLVKESVS
DKDLEVRTVRMWLLMRKLKKNEHGE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=444, Percent_Identity=24.5495495495495, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI40316845, Length=444, Percent_Identity=24.5495495495495, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI44680145, Length=437, Percent_Identity=25.4004576659039, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI44680143, Length=441, Percent_Identity=25.1700680272109, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI87082181, Length=482, Percent_Identity=99.1701244813278, Blast_Score=948, Evalue=0.0,
Organism=Escherichia coli, GI1790087, Length=460, Percent_Identity=28.4782608695652, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87082178, Length=465, Percent_Identity=26.0215053763441, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1788843, Length=391, Percent_Identity=27.1099744245524, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87081818, Length=459, Percent_Identity=25.4901960784314, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17558856, Length=493, Percent_Identity=22.5152129817444, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=463, Percent_Identity=20.7343412526998, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=238, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17542262, Length=450, Percent_Identity=22.4444444444444, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=458, Percent_Identity=23.1441048034935, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 54370; Mature: 54370

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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CCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]