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The map label for this gene is ygcS

Identifier: 30064119

GI number: 30064119

Start: 2855260

End: 2856669

Strand: Reverse

Name: ygcS

Synonym: S2980

Alternate gene names: 30064119

Gene position: 2856669-2855260 (Counterclockwise)

Preceding gene: 30064120

Following gene: 30064118

Centisome position: 62.11

GC content: 52.91

Gene sequence:

>1410_bases
ATGACGGGGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTACCGGACAATGAAGGGGTAAAGATGAACAC
TTCACCGGTGCGAATGGATGATTTACCGCTTAACCGTTTTCACTGTCGAATTGCTACGCTCACTTTCGGCGCACACCTGA
CCGACGGTTATGTTCTAGGCGTCATTGGTTACGCCATTATTCAACTTACGCCCGCCATGCAACTGACGCCGTTTATGGCG
GGAATGATCGGCGGCTCGGCGCTCCTTGGTTTGTTTCTTGGCAGCCTGGTTCTTGGGTGGATCTCCGACCATATTGGTCG
GCAAAAAATCTTCACCTTCAGCTTTTTGCTGATTACGCTCGCTTCGTTCTTGCAATTTTTTGCCACCACGCCAGAGCATC
TTATTGGGCTGCGCATTTTGATCGGCATTGGTCTGGGAGGCGATTACTCAGTAGGTCACACCTTGCTGGCTGAATTTTCC
CCGCGCCGCCATCGCGGTATTTTGCTGGGCGCATTCAGCGTGGTGTGGACCGTAGGCTATGTGTTGGCAAGTATTGCCGG
ACATCACTTTATTTCCGAAAACCCGGAGGCCTGGCGCTGGTTGCTGGCATCGGCAGCTCTGCCCGCGTTGTTGATTACGT
TATTACGCTGGGGAACGCCAGAATCGCCACGTTGGCTACTGTGCCAGGGGCGTTTTGCAGAAGCTCACGCTATCGTGCAT
CGCTATTTTGGTCCCCATGTTTTACTGGGCGATGAAGTGGTAACGGCGACCCATAAACACATCAAAACCTTGTTCTCTTC
GCGTTACTGGCGGCGCACGGCGTTTAACAGCGTCTTCTTTGTCTGCCTCGTAATCCCATGGTTTGTGATTTATACCTGGC
TGCCAACTATCGCCCAGACTATTGGTCTGGAAGATGCGCTGACTGCCAGCCTGATGCTTAATGCGTTGTTAATTGTGGGC
GCGCTGCTGGGATTAGTTCTGACGCACCTGCTGGCACATCGCAAATTTTTGCTGGGAAGTTTTTTGCTGCTGGCGGCAAC
GCTGGTAGTAATGGCCTGTTTGCCTTCCGGCAGTTCATTAACGCTGCTGCTTTTTGTTCTCTTCAGCACCACCATTTCGG
CAGTCAGTAATCTGGTGGGCATTTTGCCTGCGGAAAGTTTTCCTACTGACATTCGCTCGCTGGGAGTCGGTTTTGCCACC
GCCATGAGTCGACTTGGCGCGGCGGTAAGTACTGGCCTGCTGCCGTGGGTGCTGGCGCAGTGGGGAATGCAAGTCACCTT
ATTGCTCCTAGCGACAGTGTTGTTGGTTGGTTTTGTTGTGACCTGGCTATGGGCACCAGAAACTAAAGCCCTCCCGCTGG
TGGCGGCGGGAAATGTAGGAGGTGCGAATGAACATTCTGTTAGCGTTTAA

Upstream 100 bases:

>100_bases
GTTGCTGGAAGGGCTGAAAAAGCAGTTCGATCCTAACGGCATTATGAATACGGGTACTATCTATCCGATTGAAAAATAAT
GTATCAGGCAGCGTTCCGCG

Downstream 100 bases:

>100_bases
AGCCGAACCGGATGCCGGAATGCTGGCGGAAAAAGAGTGGCAGGCGGCGGCTCAGGGTAATAGCGGACCGGATGTTTCGC
TACTGCGAAGTTTACTCGGT

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIATLTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMA
GMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
PRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLCQGRFAEAHAIVH
RYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVG
ALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFAT
AMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Sequences:

>Translated_469_residues
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIATLTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMA
GMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
PRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLCQGRFAEAHAIVH
RYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVG
ALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFAT
AMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>Mature_468_residues
TGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIATLTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAG
MIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSP
RRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLCQGRFAEAHAIVHR
YFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGA
LLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATA
MSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507005, Length=383, Percent_Identity=26.3707571801567, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI302148518, Length=365, Percent_Identity=25.2054794520548, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4506999, Length=425, Percent_Identity=25.4117647058824, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI24497490, Length=334, Percent_Identity=26.0479041916168, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI166197673, Length=362, Percent_Identity=27.6243093922652, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI24308167, Length=465, Percent_Identity=23.4408602150538, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI23510410, Length=357, Percent_Identity=23.8095238095238, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI296080721, Length=380, Percent_Identity=26.0526315789474, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI21553331, Length=312, Percent_Identity=24.0384615384615, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI296080719, Length=380, Percent_Identity=26.0526315789474, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24497499, Length=380, Percent_Identity=26.0526315789474, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI296080734, Length=345, Percent_Identity=27.2463768115942, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI213021148, Length=475, Percent_Identity=24, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI7662270, Length=245, Percent_Identity=26.530612244898, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24497476, Length=380, Percent_Identity=25.7894736842105, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24497497, Length=347, Percent_Identity=27.3775216138329, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI20070188, Length=380, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI90669191, Length=347, Percent_Identity=27.3775216138329, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI8923870, Length=382, Percent_Identity=24.6073298429319, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI11415038, Length=374, Percent_Identity=24.0641711229947, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI166064021, Length=376, Percent_Identity=24.7340425531915, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI203098995, Length=197, Percent_Identity=27.4111675126904, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082159, Length=445, Percent_Identity=99.5505617977528, Blast_Score=866, Evalue=0.0,
Organism=Escherichia coli, GI1786229, Length=431, Percent_Identity=34.1067285382831, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1788074, Length=418, Percent_Identity=26.0765550239234, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788068, Length=451, Percent_Identity=24.6119733924612, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789207, Length=208, Percent_Identity=31.7307692307692, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790463, Length=427, Percent_Identity=23.4192037470726, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789312, Length=434, Percent_Identity=23.2718894009217, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=22.7160493827161, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082231, Length=412, Percent_Identity=23.3009708737864, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI193209824, Length=388, Percent_Identity=26.0309278350515, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565976, Length=154, Percent_Identity=29.8701298701299, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564080, Length=407, Percent_Identity=24.8157248157248, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560496, Length=395, Percent_Identity=23.7974683544304, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565978, Length=327, Percent_Identity=25.0764525993884, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17556354, Length=409, Percent_Identity=27.1393643031785, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71988651, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32564663, Length=460, Percent_Identity=23.2608695652174, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554160, Length=403, Percent_Identity=25.0620347394541, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=183, Percent_Identity=32.2404371584699, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324469, Length=514, Percent_Identity=21.2062256809339, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24649618, Length=338, Percent_Identity=25.7396449704142, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19922616, Length=394, Percent_Identity=25.3807106598985, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649622, Length=387, Percent_Identity=24.031007751938, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24668456, Length=409, Percent_Identity=25.1833740831296, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668440, Length=406, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640198, Length=434, Percent_Identity=22.8110599078341, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640196, Length=434, Percent_Identity=22.8110599078341, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640200, Length=434, Percent_Identity=22.8110599078341, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649616, Length=356, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161078338, Length=399, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647365, Length=404, Percent_Identity=25.990099009901, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922874, Length=408, Percent_Identity=24.7549019607843, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077756, Length=435, Percent_Identity=23.448275862069, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50837; Mature: 50706

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIATLTFGAHLTDGYVLG
CCCCEEECCCCCCCEECCCCCCCEECCCCCEECCCCCCHHEEEEEEEEECCCCCCCHHHH
VIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGY
HHHHHHHHCCHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHH
VLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLCQGRFAEAHAIVH
HHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHH
RYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQT
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIATLTFGAHLTDGYVLG
CCCEEECCCCCCCEECCCCCCCEECCCCCEECCCCCCHHEEEEEEEEECCCCCCCHHHH
VIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGY
HHHHHHHHCCHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHH
VLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLCQGRFAEAHAIVH
HHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHH
RYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQT
HHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]