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The map label for this gene is hypA

Identifier: 30064080

GI number: 30064080

Start: 2813595

End: 2813957

Strand: Direct

Name: hypA

Synonym: S2935

Alternate gene names: 30064080

Gene position: 2813595-2813957 (Clockwise)

Preceding gene: 30064070

Following gene: 30064081

Centisome position: 61.17

GC content: 52.89

Gene sequence:

>363_bases
ATGGGAGGCGATATGCACGAAATAACCCTCTGCCAACGGGCACTGGAATTGATCGAACAGCAGGCCGCAAAACACGGCGC
AAAACGCGTAACTGGGGTCTGGCTCAAAATTGGCGCATTTTCTTGTGTCGAAACCAGCTCTCTTGCCTTTTGTTTTGATC
TGGTTTGCCGCGGCAGCGTGGCGGAAGGTTGTAAACTGCACCTCGAAGAACAAGAGGCCGAATGCTGGTGTGAAACATGC
CAACAGTATGTGACGCTACTGACCCAGCGCGTCCGCCGCTGTCCACAGTGTCATGGTGACATGCTACAGATTGTGGCAGA
CGACGGTTTACAGATTCGGCGGATAGAAATAGACCAGGAGTGA

Upstream 100 bases:

>100_bases
TTCGTCGCCGTGTCGACGTGTCATTTCGACATCATCGACATTATTCACCGCAGGGATAATCAACACTGGCGCAATTATTG
CTTGTAGCTGGCAATAGTTA

Downstream 100 bases:

>100_bases
GCGATGTGTACAACATGCGGTTGCGGTGAAGGCAACCTGTATATCGAGGGTGATGAACATAACCCTCATTCCGCGTTTCG
TAGCGCGCCATTTGCCCCGG

Product: hydrogenase nickel incorporation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MGGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETC
QQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE

Sequences:

>Translated_120_residues
MGGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETC
QQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
>Mature_119_residues
GGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQ
QYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE

Specific function: Not required for the formation of hydrogenases 1 and 2. Plays probably a regulatory role [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789081, Length=116, Percent_Identity=100, Blast_Score=234, Evalue=9e-64,
Organism=Escherichia coli, GI1789365, Length=114, Percent_Identity=48.2456140350877, Blast_Score=117, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 13529; Mature: 13398

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
10.8 %Cys+Met (Translated Protein)
8.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
AEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
GGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
AEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]