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The map label for this gene is emrR

Identifier: 30064050

GI number: 30064050

Start: 2779303

End: 2779833

Strand: Direct

Name: emrR

Synonym: S2898

Alternate gene names: 30064050

Gene position: 2779303-2779833 (Clockwise)

Preceding gene: 30064049

Following gene: 30064051

Centisome position: 60.43

GC content: 48.96

Gene sequence:

>531_bases
ATGGATAGTTCGTTTACGCCCATTGAACAAATGCTAAAATTTCGCGCCAGCCGCCACGAAGATTTTCCTTATCAGGAGAT
CCTTCTGACTCGTCTTTGCATGCACATGCAAAGCAAGCTGCTGGAGAACCGCAATAAAATGCTGAAGGCTCAGGGGATTA
ACGAGACGTTGTTTATGGCGTTGATTACGCTGGAGTCTCAGGAAAACCACAGTATTCAGCCTTCTGAATTAAGTTGTGCT
CTTGGATCATCCCGTACCAACGCGACGCGTATTGCCGATGAACTGGAAAAACGCGGTTGGATCGAACGTCGTAAAAGCGA
TAACGATCGCCGCTGCCTGCATCTGCAATTAACGGAAAAAGGTCACGAGTTTTTGCGCGAGGTTTTACCACCGCAGCATA
ACTGCCTGCATCAACTCTGGTCCGCGCTCAGCACAACAGAAAAAGATCAGCTCGAGCAAATCACCCGCAAATTGCTCTCC
CGTCTCGACCAGATGGAACAAGACGGTGTGGTTCTCGAAGCGATGAGCTAA

Upstream 100 bases:

>100_bases
GATTATATAACCCACAAGAATCATTTTTCTAAAACAATACATTTACTTTATTTGTCACTGTCGTTACTATATCGGCTGAA
ATTAATGAGGTCATACCCAA

Downstream 100 bases:

>100_bases
CGCGTCATCTCGCTCAAAAATCCAGATTTATAAAAGAAAAAATGACCGGCCAGCATCGCAACATGCTGGCCTTTTTGGCA
AGCAGGTCGGCTCAGCCGAT

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRKSDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
RLDQMEQDGVVLEAMS

Sequences:

>Translated_176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRKSDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
RLDQMEQDGVVLEAMS
>Mature_176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRKSDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
RLDQMEQDGVVLEAMS

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=176, Percent_Identity=99.4318181818182, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 20563; Mature: 20563

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRKSDNDRRCLHLQLTEK
HHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
GHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLSRLDQMEQDGVVLEAMS
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRKSDNDRRCLHLQLTEK
HHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHH
GHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLSRLDQMEQDGVVLEAMS
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]