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The map label for this gene is gatR

Identifier: 30063529

GI number: 30063529

Start: 2158719

End: 2159498

Strand: Reverse

Name: gatR

Synonym: S2275

Alternate gene names: 30063529

Gene position: 2159498-2158719 (Counterclockwise)

Preceding gene: 30063530

Following gene: 30063527

Centisome position: 46.95

GC content: 46.54

Gene sequence:

>780_bases
ATGACGATGAATTCATTCGAGCGAAGGAATAAGATCATCCAATTAGTGAATGAACAGGGAACCGTGCTTGTTCAGGATCT
GGCGGGAGTATTTGCTGCCTCGGAAGCGACAATCCGTGCCGATTTGCGCTTTCTCGAACAAAAAGGCGTGGTTACGCGCT
TTCATGGCGGTGCGGCGAAAATAATGTCCGGTAATAGTGAAACCGAGACCCAGGAAGTCGGGTTTAAAGAGCGATTTCAG
CTCGCCAGCGCGCCAAAAAACAGAATAGCGCAGGCGGCAGTCAAAATGATCCATGAAGGGATGACCGTTATTCTCGACAG
CGGAAGTACCACAATGCTTATCGCCGAAGGATTAATGACCGCTAAAAATATCACGGTGATTACCAACAGTCTCCCGGCAG
CGTTTGCCCTTTCCGAAAATAAAGACATTACTCTGGTCGTCTGTGGTGGCACGGTCCGCCATAAAACGCGCTCGATGCAT
GGTTCCATTGCCGAGCGTTCATTGCAGGATATTAATGCCGATTTAATGTTTGTCGGTGCTGATGGTATTGATGCGGTTAA
TGGTATTACGACCTTTAATGAAGGTTATTCGATTAGCGAGGCGATGGTCACCGCCGCAAATAAAGTGATTGCCGTTCTCG
ATTCATCGAAATTTAATCGTCGCGGTTTTAATCAGGTACTGCCAATCGAAAAAATTGACATTATTGTTACCGATGATGCT
GTGTCAGAGGTGGATAAATTGGCATTGCAGAAGACACGGGTAAAATTAATTACGGTGTAG

Upstream 100 bases:

>100_bases
AAACCGCGGGCCAGCGTGATGCTGGCCCGGTATTGTGCAAAACAGATCATTCACCAATGGTCCCCCTTCGTTTACACTAG
CCACAATTGAATATGGGTAA

Downstream 100 bases:

>100_bases
TATTGTTCTGTATGCCGGATAAGGTGTTTACACCGCATCCGGCATTACGGATTCTCCCTGGTTCAAGAGAGAATAGTTTG
ATTAACGCAATAATGGACAA

Product: galactitol utilization operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISEAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIVTDDA
VSEVDKLALQKTRVKLITV

Sequences:

>Translated_259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISEAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIVTDDA
VSEVDKLALQKTRVKLITV
>Mature_258_residues
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQL
ASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHG
SIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISEAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIVTDDAV
SEVDKLALQKTRVKLITV

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=37.4015748031496, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=38.671875, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=30.859375, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=32.0675105485232, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=29.1139240506329, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787540, Length=259, Percent_Identity=29.3436293436293, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=25.296442687747, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=261, Percent_Identity=24.904214559387, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28018; Mature: 27886

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISEAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIVTDDA
CCCCHHCCEEECCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHH
VSEVDKLALQKTRVKLITV
HHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure 
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISEAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIVTDDA
CCCCHHCCEEECCCCCCHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECHH
VSEVDKLALQKTRVKLITV
HHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]