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The map label for this gene is udk

Identifier: 30063515

GI number: 30063515

Start: 2130707

End: 2131348

Strand: Reverse

Name: udk

Synonym: S2254

Alternate gene names: 30063515

Gene position: 2131348-2130707 (Counterclockwise)

Preceding gene: 30063516

Following gene: 30063514

Centisome position: 46.34

GC content: 48.75

Gene sequence:

>642_bases
ATGACTGATCAGTCTCATCAGTGCGTCATTATCGGTATCGCTGGCGCATCGGCTTCCGGCAAGAGTCTTATTGCCAGTAC
CCTTTATCGTGAATTACGTGAGCAAGTCGGTGATGAACACATCGGCGTAATTCCCGAAGACTGCTATTACAAAGATCAAA
GCCATCTGTCGATGGAAGAACGCGTTAAGACCAACTACGACCATCCCAGCGCGATGGATCACAGCCTGTTGCTTGAGCAT
TTACAAGCGTTGAAACGCGGCTCGGCAATTGACCTGCCGGTTTACAGCTATGTTGAACATACGCGTATGAAAGAAACGGT
GACGGTTGAGCCGAAGAAGGTCATCATTCTCGAAGGCATTTTGTTGCTGACGGATGCGCGTTTGCGTGACGAACTTAACT
TCTCCATTTTCGTTGATACCCCGCTGGATATCTGCCTGATGCGCCGCATCAAGCGTGACGTTAACGAGCGTGGGCGTTCA
ATGGATTCCGTGATGGCGCAATATCAAAAAACCGTGCGCCCGATGTTCCTGCAATTCATTGAGCCTTCTAAACAATATGC
GGACATTATCGTGCCGCGCGGCGGGAAAAACCGCATCGCGATCGATATATTGAAAGCGAAAATAAGTCAGTTCTTTGAAT
AA

Upstream 100 bases:

>100_bases
CTATTCGACTGGTATCAGACGGATGAAATCCCTATAATTGCCGCGTTTGGCGCTTCGTCGCCCCCTTCCTAACATCCAGG
TTAATCAGGTCGCTAAATAT

Downstream 100 bases:

>100_bases
GCTTGATAAATTGTGTACCGTTCAGTGATAAGTTGGTATGCCCTTGACGTAATTGGCGTTAAGGGAGTGATGTGCGAAAG
GAGAAAATGCCATGCGTCTG

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEH
LQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Sequences:

>Translated_213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEH
LQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>Mature_212_residues
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHL
QALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSM
DSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=203, Percent_Identity=37.4384236453202, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI57863312, Length=203, Percent_Identity=39.4088669950739, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI301129207, Length=203, Percent_Identity=39.4088669950739, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=35.5450236966825, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI209863022, Length=159, Percent_Identity=32.7044025157233, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=100, Blast_Score=440, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=37.6811594202899, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=37.6811594202899, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=35.1851851851852, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=150, Percent_Identity=34.6666666666667, Blast_Score=112, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573516, Length=203, Percent_Identity=39.4088669950739, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573514, Length=203, Percent_Identity=39.4088669950739, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28573512, Length=203, Percent_Identity=39.4088669950739, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45550449, Length=203, Percent_Identity=39.4088669950739, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI221458995, Length=219, Percent_Identity=35.1598173515982, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24649624, Length=218, Percent_Identity=34.8623853211009, Blast_Score=147, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_ECO57 (P0A8F6)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- RefSeq:   NP_288574.2
- RefSeq:   NP_310900.2
- ProteinModelPortal:   P0A8F6
- SMR:   P0A8F6
- EnsemblBacteria:   EBESCT00000024765
- EnsemblBacteria:   EBESCT00000058653
- GeneID:   916575
- GeneID:   956798
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3234
- KEGG:   ecs:ECs2873
- GeneTree:   EBGT00050000009857
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- BioCyc:   ECOL83334:ECS2873-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24354; Mature: 24222

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEE
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHCCHHH
RVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEHHH
LLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEE
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHCCHHH
RVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGI
HHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCEEEEEHHH
LLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796