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The map label for this gene is yoaE

Identifier: 30062930

GI number: 30062930

Start: 1485639

End: 1487189

Strand: Direct

Name: yoaE

Synonym: S1527

Alternate gene names: 30062930

Gene position: 1485639-1487189 (Clockwise)

Preceding gene: 30062922

Following gene: 30062935

Centisome position: 32.3

GC content: 53.9

Gene sequence:

>1551_bases
ATGGAATTCTTAATGGACCCCTCAATTTGGGCGGGGCTACTCACGCTTGTTGTTCTCGAAATTGTGCTGGGTATCGATAA
CCTGGTCTTCATCGCCATTCTTGCTGACAAACTGCCGCCAAAACAACGCGATAAAGCGCGTTTGCTGGGGTTATCACTGG
CGCTGATTATGCGTCTGGGGCTGCTGTCGCTGATTTCATGGATGGTCACGCTGACCAAACCGCTATTTACCGTCATGGAT
TTCTCCTTCTCCGGACGCGATCTGATTATGTTGTTCGGGGGGATATTCTTGCTGTTCAAAGCAACAACCGAACTGCATGA
ACGGCTGGAAAACCGCGATCATGATTCCGGCCACGGTAAAGGCTACGCCAGTTTCTGGGTGGTCGTCACACAGATTGTCA
TCCTTGACGCCGTCTTCTCGTTGGATGCGGTAATTACTGCAGTAGGGATGGTTAACCATCTGCCGGTGATGATGGCGGCG
GTAGTGATTGCGATGGCGGTTATGTTGCTGGCATCGAAACCGCTGACGCGATTCGTTAACCAGCACCCCACGGTGGTGGT
GCTCTGTCTGAGCTTCCTGTTAATGATTGGTCTGAGTCTGGTGGCAGAAGGTTTCGGTTTCCACATTCCGAAAGGTTACC
TGTATGCCGCGATTGGCTTCTCGATCATTATCGAAGTGTTTAACCAGATTGCGCGTCGCAACTTTATTCGTCACCAGTCG
ACTTTGCCGCTGCGAGCGCGTACTGCCGATGCCATCCTGCGTTTGATGGGCGGGAAACGTCAGGCCAATGTTCAGCACGA
TGCCGATAACCCGATGCCGATCCCGGAAGGTGCATTTGCCGAAGAAGAACGGTACATGATTAACGGCGTACTGACGCTGG
CGTCGCGTTCTCTGCGCGGGATCATGACGCCGCGCGGTGAAATAAGCTGGGTTGACGCTAATCTCGGGGTCGATGAAATC
CGCGAGCAACTGCTCTCTTCACCGCACAGTCTGTTCCCGGTATGTCGCGGTGAACTGGATGAAATCATCGGTATCGTACG
TGCTAAAGAACTGCTGGTGGCGCTGGAAGAGGGCGTTGATGTGGCGGCGATTGCTTCGGCGTCTCCGGCGATTATCGTCC
CGGAAACCCTCGATCCGATCAACCTGCTGGGCGTGCTGCGTCGCGCTCGCGGGAGCTTTGTTATCGTGACCAACGAGTTT
GGTGTGGTACAAGGCTTGGTCACGCCGCTGGATGTGCTGGAAGCCATTGCGGGTGAATTCCCGGACGCTGACGAAACGCC
GGAAATCATTACCGATGGTAACGGCTGGCTGGTAAAAGGCGGTACAGATTTGCATGCCTTGCAGCAGGCGCTTGATGTTG
AGCACCTTGCCGATGACGATGATATCGCGACGGTCGCGGGCCTCGTGATCTCGGCAAATGGTCACATTCCCCGTGTGGGC
GATGTGATTGATGTAGGGCCACTGCATATCACCATCTTTGAAGCCAATGATTATCGTGTTGATCTGGTTCGCATTGTTAA
AGAGCAACCGGCGCACGATGAAGATGAGTAA

Upstream 100 bases:

>100_bases
GCCTTTCTGGCACTCTATGCCGCACCTTTCGTTTGCATTTTGTCGTTACGCCTGCATTATTTCTGGCGTCGAATAGCTAT
TCCTTAAGCAGGAGCTTGTC

Downstream 100 bases:

>100_bases
GCGTTAACGTAACGACATAATGGGCGTGATATGTCCATTATGCCGGGCGGGCGGCGGTTGGCTGCCCGCCAGCCATTTGG
GAAAATCACGTAGCGGCATC

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMD
FSFSGRDLIMLFGGIFLLFKATTELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQANVQHDADNPMPIPEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEI
REQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRARGSFVIVTNEF
GVVQGLVTPLDVLEAIAGEFPDADETPEIITDGNGWLVKGGTDLHALQQALDVEHLADDDDIATVAGLVISANGHIPRVG
DVIDVGPLHITIFEANDYRVDLVRIVKEQPAHDEDE

Sequences:

>Translated_516_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMD
FSFSGRDLIMLFGGIFLLFKATTELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQANVQHDADNPMPIPEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEI
REQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRARGSFVIVTNEF
GVVQGLVTPLDVLEAIAGEFPDADETPEIITDGNGWLVKGGTDLHALQQALDVEHLADDDDIATVAGLVISANGHIPRVG
DVIDVGPLHITIFEANDYRVDLVRIVKEQPAHDEDE
>Mature_516_residues
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMD
FSFSGRDLIMLFGGIFLLFKATTELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQANVQHDADNPMPIPEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEI
REQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRARGSFVIVTNEF
GVVQGLVTPLDVLEAIAGEFPDADETPEIITDGNGWLVKGGTDLHALQQALDVEHLADDDDIATVAGLVISANGHIPRVG
DVIDVGPLHITIFEANDYRVDLVRIVKEQPAHDEDE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=253, Percent_Identity=24.1106719367589, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788119, Length=518, Percent_Identity=99.2277992277992, Blast_Score=997, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=519, Percent_Identity=50.0963391136802, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1789197, Length=232, Percent_Identity=48.7068965517241, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1790664, Length=240, Percent_Identity=27.0833333333333, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786879, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693175, Length=235, Percent_Identity=29.3617021276596, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 56334; Mature: 56334

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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CEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]