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The map label for this gene is mppA [H]

Identifier: 30062850

GI number: 30062850

Start: 1392226

End: 1393860

Strand: Direct

Name: mppA [H]

Synonym: S1424

Alternate gene names: 30062850

Gene position: 1392226-1393860 (Clockwise)

Preceding gene: 30062847

Following gene: 30062852

Centisome position: 30.27

GC content: 47.77

Gene sequence:

>1635_bases
ATGTCGGTTAGAGGGAAACTTATGAAGCACTCTGTTTCAGTTACGTGTTGTGCGCTGTTGGTCAGCAGCATTTCTCTTTC
GTATGCTGCAGAAGTTCCGAGCGGCACAGTACTGGCAGAGAAGCAGGAGCTGGTGCGCCACATTAAAGATGAGCCTGCGT
CGCTGGATCCCGCTAAAGCCGTGGGCCTGCCAGAGATTCAGGTCATTCGCGATCTGTTTGAAGGTCTGGTGAATCAGAAC
GAAAAAGGGGAGATTGTCCCCGGCGTCGCGACTCAATGGAAAAGTAATGACAACCGTATCTGGACTTTTACCCTGCGCGA
TAACGCAAAATGGGCGGATGGCACACCGGTAACGGCGCAAGATTTTGTCTACAGCTGGCAACGTCTGGTGGACCCAAAAA
CATTGTCGCCATTTGCATGGTTTGCCGCGCTGGCGGGAATCAACAACGCACAGGCGATTATTGATGGTAAAGCTACGCCT
GATCAGCTTGGCGTCACCGCAGTTGATGCCCATACTTTGAAAATTCAGCTTGATAAACCGTTGCCGTGGTTTGTGAATTT
AACCGCTAACTTTGCCTTCTTCCCGGTGCAAAAAGCCAACGTAGAAAGCGGTAAAGAGTGGACGAAACCCGGAAATCTGA
TCGGCAATGGCGCTTATGTTCTTAAAGAGCGCGTAGTCAATGAAAAACTGGTCGTGGTACCGAATACCCATTATTGGGAT
AACGCCAAAACGGTGCTGCAAAAAGTGACCTTCCTGCCAATTAATCAGGAATCCGCAGCCACTAAGCGTTACCTCGCGGG
GGATATTGATATCACCGAATCCTTCCCGAAAAATATGTATCAGAAGCTGTTGAAGGATATTCCGGGGCAGGTTTATACGC
CACCGCAGCTCGGGACCTATTATTATGCCTTTAACACGCAAAAAGGGCCGACGGCAGATCAGCGCGTTCGCCTGGCATTA
AGTATGACGATAGATCGCCGCCTGATGACCGAAAAAGTGTTGGGGACGGGCGAAAAGCCAGCGTGGCATTTTATACCAGA
TGTTACCGCCGGATTTACGCCGGAACCTTCGCCGTTTGAACAAATGAGTCAGGAAGAACTGAATGCGCAGGCAAAAACTT
TGTTGAGCGCAGCTGGTTATGGTCCGCAAAAACCGCTGAAGCTGACGCTTTTGTATAACACTTCAGAAAACCATCAAAAA
ATTGCGATTGCTGTAGCATCGATGTGGAAAAAGAACCTTGGCGTAGATGTTAAATTGCAAAATCAGGAATGGAAAACCTA
TATCGATAGCCGTAACACCGGCAATTTTGATGTTATCCGCGCCTCATGGGTGGGGGATTATAATGAACCCTCCACTTTCC
TGACATTATTAACGTCAATGCATTCAGGAAATATTTCACGCTTTAACAATCCGGCATACGACAAAGTTCTGGCCCAGGCA
TCGACGGAAAATACCGTTAAAGCGCGTAATGCCGATTACAACGCGGCAGAAAAAATCCTCATGGAGCAAGCACCGATTGC
ACCAATTTATCAATATACCAATGGACGATTAATCAAACCGTGGCTGAAAGGTTATCCCATTAATAACCCTGAAGATGTAG
CGTACAGTCGGACTATGTATATTGTGAAGCATTGA

Upstream 100 bases:

>100_bases
ATATTGATACTTAAAACATTTGATGCTTCCTTTGTCACTTTTTTGATGGAAGTTGTTTGCATTTCTTTAAGGCGAAACAA
ATAATTACGCATCAATTTTA

Downstream 100 bases:

>100_bases
TGTGATGGGAACTGGCGTTACCCTTGTGGATAACGCCAGTGATGTCTGATTTAGCGCCCCTGTTCCGGCGGTGTAATGTT
ATCCATATACAGCGTCTGGC

Product: putative transport periplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSVRGKLMKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQN
EKGEIVPGVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATP
DQLGVTAVDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWD
NAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLAL
SMTIDRRLMTEKVLGTGEKPAWHFIPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQK
IAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSMHSGNISRFNNPAYDKVLAQA
STENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH

Sequences:

>Translated_544_residues
MSVRGKLMKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQN
EKGEIVPGVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATP
DQLGVTAVDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWD
NAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLAL
SMTIDRRLMTEKVLGTGEKPAWHFIPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQK
IAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSMHSGNISRFNNPAYDKVLAQA
STENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH
>Mature_543_residues
SVRGKLMKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNE
KGEIVPGVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPD
QLGVTAVDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDN
AKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALS
MTIDRRLMTEKVLGTGEKPAWHFIPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKI
AIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSMHSGNISRFNNPAYDKVLAQAS
TENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=99.6275605214153, Blast_Score=1106, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=48.0225988700565, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=42.1550094517958, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1787762, Length=538, Percent_Identity=28.4386617100372, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789887, Length=476, Percent_Identity=25.6302521008403, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1789966, Length=466, Percent_Identity=22.1030042918455, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787052, Length=508, Percent_Identity=22.0472440944882, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60715; Mature: 60584

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRGKLMKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKA
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHH
VGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCCCCCCCHH
DFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTAVDAHTLKIQLDKP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHCCEEEEEEEEEEEEECCC
LPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWD
CCEEEEEEECEEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCC
NAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTY
CHHHHHHHHHEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEE
YYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPAWHFIPDVTAGFTPEPSPFE
EEEEECCCCCCHHHHEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHH
QMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQ
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEC
NQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSMHSGNISRFNNPAYDKVLAQA
CCHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
STENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMY
CCCCCEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEE
IVKH
EEEC
>Mature Secondary Structure 
SVRGKLMKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKA
CCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEHHHHHHHHHHCCCCCCCCHHHH
VGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEEECCCCCCCCCCCCHH
DFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTAVDAHTLKIQLDKP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHCCEEEEEEEEEEEEECCC
LPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWD
CCEEEEEEECEEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHCCCEEEEECCCCCCC
NAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTY
CHHHHHHHHHEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEE
YYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPAWHFIPDVTAGFTPEPSPFE
EEEEECCCCCCHHHHEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCHHH
QMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVASMWKKNLGVDVKLQ
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEEC
NQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSMHSGNISRFNNPAYDKVLAQA
CCHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHC
STENTVKARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMY
CCCCCEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECHHHCCCCCCCCCCCEEEEEEE
IVKH
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]