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The map label for this gene is bioC

Identifier: 30062262

GI number: 30062262

Start: 750506

End: 751261

Strand: Direct

Name: bioC

Synonym: S0768

Alternate gene names: 30062262

Gene position: 750506-751261 (Clockwise)

Preceding gene: 30062261

Following gene: 30062263

Centisome position: 16.32

GC content: 56.22

Gene sequence:

>756_bases
ATGGCAACGGTTAATAAACAAGCCATTGCAGCGGCATTTGGTCGGGCAGCCGCACACTATGAGCAACATGCAGATCTACA
GCGCCAGAGTGCTGACGCCTTACTGGCAATGCTTCCACAGCGTAAATACACCCACGTACTGGACGCGGGTTGTGGACCTG
GCTGGATGAGCCGCCACTGGCGGGAACGTCACGCGCAGGTGACGGCGTTAGATCTCTCGCCGCCAATGCTTGCGCAAGCC
CGCCATAAAGATGCCGCAGATCATTATCTGGCAGGAGATATCGAATCCCTGCCGTTAGCGACTGCGACGTTCGATCTTGC
ATGGAGCAATCTCGCGGTGCAGTGGTGCGGTAATTTATCCACGGCACTCCGCGAGCTGTATCGGGTGGTGCGCCCCGGAG
GCGTGGTCGCGTTTACCACGCTGGTGCAGGGATCGTTACCCGAACTGCATCAGGCGCGGCAGGCGGTGGACGAGCGTCCG
CATGCTAATCGCTTTTTACCGCCAGATGAAATCGAAGAGTCGCTGAACGGCGTGCGTTATCAACATCATATTCAGCTCAT
CACACTATGGTTTGATGATGCGCTCAGTGCCATGCGTTCGCTGAAAGGCATCGGTGCTACGCATCTTCATGAAGGGCGCG
ACCCGCGAATATTAACGCGTTCGCAGTTGCAGCGATTGCAACTGGCCTGGCCGCAACAACAGGGGCGATATCCTCTGACG
TATCATCTTTTTTTGGGAGTGATTGCTCGTGAGTAA

Upstream 100 bases:

>100_bases
ATTCGCCCGCCAACCGTACCCGCTGGTACTGCGCGACTGCGCTTAACGCTAACCGCTGCGCATGAAATGCAGGATATCGA
CCGTCTGCTGGAGGTGCTGC

Downstream 100 bases:

>100_bases
ACGTTATTTTGTCACCGGAACGGATACCGAAGTGGGGAAAACCGTCGCCAGTTGTGCACTTTTACAAGCCGCGAAGGCAG
TAGGTTATCGGACGGCAGGT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLAQA
RHKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQARQAVDERP
HANRFLPPDEIEESLNGVRYQHHIQLITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLT
YHLFLGVIARE

Sequences:

>Translated_251_residues
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLAQA
RHKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQARQAVDERP
HANRFLPPDEIEESLNGVRYQHHIQLITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLT
YHLFLGVIARE
>Mature_250_residues
ATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLAQAR
HKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQARQAVDERPH
ANRFLPPDEIEESLNGVRYQHHIQLITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTY
HLFLGVIARE

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=97.2111553784861, Blast_Score=473, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28192; Mature: 28061

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHH
RERHAQVTALDLSPPMLAQARHKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLS
HHHCCEEEEEECCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
TALRELYRVVRPGGVVAFTTLVQGSLPELHQARQAVDERPHANRFLPPDEIEESLNGVRY
HHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEE
QHHIQLITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLT
EHHEEEEEEHHHHHHHHHHHHHCCCCHHHCCCCCCCEECHHHHHHHHHCCCHHCCCCCCH
YHLFLGVIARE
HHHHHHHHHCC
>Mature Secondary Structure 
ATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHH
RERHAQVTALDLSPPMLAQARHKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLS
HHHCCEEEEEECCCCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
TALRELYRVVRPGGVVAFTTLVQGSLPELHQARQAVDERPHANRFLPPDEIEESLNGVRY
HHHHHHHHHHCCCCCEEHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCEE
QHHIQLITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLT
EHHEEEEEEHHHHHHHHHHHHHCCCCHHHCCCCCCCEECHHHHHHHHHCCCHHCCCCCCH
YHLFLGVIARE
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]