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The map label for this gene is ybbF

Identifier: 30062008

GI number: 30062008

Start: 471543

End: 472265

Strand: Reverse

Name: ybbF

Synonym: S0463

Alternate gene names: 30062008

Gene position: 472265-471543 (Counterclockwise)

Preceding gene: 30062009

Following gene: 30062007

Centisome position: 10.27

GC content: 53.94

Gene sequence:

>723_bases
GTGGCGACACTCTTTATTGCAGATCTTCATCTCTGCGTGGAAGAACCGGCGATCACCGCCGGTTTTCTGCGTTTTTTAGC
GGGGGAAGCCCGCAAGGCCGACGCGCTGTATATTCTTGGCGATCTGTTTGAAGCATGGATTGGCGACGACGATCCCAACC
CACTCCATCGCCAGATGGCGGCAGCGATCAAAGCGGTGTCCGATTCCGGCGTTCCCTGTTATTTCATTCATGGCAACCGT
GATTTTCTGCTCGGCAAACGCTTTGCCCGTGAAAGCGGCATGACATTATTGCCGGAAGAAAAGGTGCTCGAACTTTATGG
TCGCCGGGTGTTGATTATGCATGGCGACACGCTGTGCACCGATGACGCGGGTTATCAGGCTTTTCGCGCCAAAGTCCACA
AACCCTGGCTGCAAATGCTATTCCTCGCCCTGCCGTTGTTTGTGCGCAAACGCATTGCCGCGCGAATGCGCGCGAACAGC
AAAGAAGCCAACAGCAGTAAATCGCTGGCGATCATGGACGTTAACCAAAACGCTGTGGTCAGTGCGATGGAAAAACATCA
GGTGCAATGGCTAATCCACGGGCATACCCATCGCCCGGCGGTGCATGAACTTATCGCCAACCAGCAACCTGCTTTTCGCG
TGGTACTGGGTGCCTGGCATACGGAAGGTTCGATGGTGAAAGTCACGGCTGATGACGTTGAGCTGATTCATTTTCCGTTT
TAA

Upstream 100 bases:

>100_bases
TAGACAAAATCAAAGGTGTTGCAACCGGTCGTAACGGTATGCACCAGGACGTGCCAAAAGAAGACGTTATCATTGAAAGC
GTGACCGTTAGCGAGTAATC

Downstream 100 bases:

>100_bases
AAAACCCACAACTTTGCTGATTTCACAGCCACGCAACCGTTTTCCTTGCTCTCTTTCCGTGCTATTCTCTGTGCCCTCTA
AAGCCGAGAGTTGTGCACCA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNR
DFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANS
KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Sequences:

>Translated_240_residues
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNR
DFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANS
KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>Mature_239_residues
ATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRD
FLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSK
EANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family

Homologues:

Organism=Escherichia coli, GI1786735, Length=240, Percent_Identity=99.1666666666667, Blast_Score=493, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPXH_ECO24 (A7ZIT3)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461712.1
- ProteinModelPortal:   A7ZIT3
- SMR:   A7ZIT3
- STRING:   A7ZIT3
- EnsemblBacteria:   EBESCT00000021905
- GeneID:   5589752
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0563
- eggNOG:   COG2908
- GeneTree:   EBGT00050000010081
- HOGENOM:   HBG288883
- OMA:   CHGDTLC
- ProtClustDB:   PRK05340
- BioCyc:   ECOL331111:ECE24377A_0563-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00575
- InterPro:   IPR004843
- InterPro:   IPR010138
- TIGRFAMs:   TIGR01854

Pfam domain/function: PF00149 Metallophos

EC number: 3.6.1.-

Molecular weight: Translated: 26925; Mature: 26793

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMA
CCEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHH
AAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCT
HHHHHHCCCCCEEEEEECCCCEEHHHHHHHHCCCEECCHHHHHHHHCCEEEEEECCEEEC
DDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHH
SAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
HHHHHHCEEEEEECCCCCHHHHHHHCCCCCCEEEEEEEEECCCCEEEEECCCEEEEEECC
>Mature Secondary Structure 
ATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMA
CEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHH
AAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCT
HHHHHHCCCCCEEEEEECCCCEEHHHHHHHHCCCEECCHHHHHHHHCCEEEEEECCEEEC
DDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHH
SAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
HHHHHHCEEEEEECCCCCHHHHHHHCCCCCCEEEEEEEEECCCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA