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The map label for this gene is hisK [H]

Identifier: 29349665

GI number: 29349665

Start: 5607645

End: 5608436

Strand: Reverse

Name: hisK [H]

Synonym: BT_4257

Alternate gene names: 29349665

Gene position: 5608436-5607645 (Counterclockwise)

Preceding gene: 29349666

Following gene: 29349662

Centisome position: 89.59

GC content: 45.83

Gene sequence:

>792_bases
ATGAGGACGAATTATCACACCCACACCACCCGCTGCCTCCATGCGACAGGGAGTGACGAAGAATTTGTTTTAAGCGCCAT
CAAAGGCGGCTATCAGGAACTTGGTTTCTCTGACCACACACCATGGGAATACCATACCGATTATGTATCCGACATCCGGA
TGACTCCCGAAGAACTGCCGGAGTATGTAGAAAGCCTCCGCTCGCTACAAAAGAAATATAAAGATCAAATCAGCATTAAA
ATCGGCTTGGAATGTGAATATTTTCCGGAGTATATTCCCTGGCTGAAAGGAGTTATCAAGGAGTATCAACTGGATTACAT
CATCTTCGGCAACCACCATTTCCATACAGATGAGAAGTTTCCTTATTTCGGGCGAAATACCCATACGGTAGATATGCTTG
AACTTTATGAAGAGAGTGCGATTGAAGGGATGGAAAGCGGCTTGTTTGCCTATCTGGCACATCCCGACCTGTTCATGCGT
TCATATCCTGAATTCGACCGTCATTGTAAACTTGTCAGCAGACACATCTGCCGGACAGCAGCCCGCTTGAACCTGCCCCT
GGAATATAATATAGGTTACGAAGACTACAACGATGAACATGGAATAACAACCATTCCCCACCCTGCTTTTTGGGAAATAG
CAGCACACGAAGGCTGCACCGCCATTATCGGAGTGGATGCCCACAACAACCAATATCTTGAAACTCCGTTCTACTATGAC
CGGGCAAATGAGACTCTCCAAAAGCTGGGGATGAAAGTGACAGACAGAATTCCTTTCCTCAACGAAAAATAA

Upstream 100 bases:

>100_bases
CCCGCAGCTTATAAAGCAGGCATCTGCTTCCCATTTCAAATAGTAGAAGAAGTTCCGGCAGAAGCATTCGACATCTGCAT
GGACATAATTATAACAAGTA

Downstream 100 bases:

>100_bases
TGTTTGTGATAACCGTAGCCCCTACTCTCTGATTCAGAGTACGCACCAGAAGTTCCCGTCCCATCATCAGTTCCTGACGA
AGGGCGGCGGAAGTGAGATG

Product: putative histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRTNYHTHTTRCLHATGSDEEFVLSAIKGGYQELGFSDHTPWEYHTDYVSDIRMTPEELPEYVESLRSLQKKYKDQISIK
IGLECEYFPEYIPWLKGVIKEYQLDYIIFGNHHFHTDEKFPYFGRNTHTVDMLELYEESAIEGMESGLFAYLAHPDLFMR
SYPEFDRHCKLVSRHICRTAARLNLPLEYNIGYEDYNDEHGITTIPHPAFWEIAAHEGCTAIIGVDAHNNQYLETPFYYD
RANETLQKLGMKVTDRIPFLNEK

Sequences:

>Translated_263_residues
MRTNYHTHTTRCLHATGSDEEFVLSAIKGGYQELGFSDHTPWEYHTDYVSDIRMTPEELPEYVESLRSLQKKYKDQISIK
IGLECEYFPEYIPWLKGVIKEYQLDYIIFGNHHFHTDEKFPYFGRNTHTVDMLELYEESAIEGMESGLFAYLAHPDLFMR
SYPEFDRHCKLVSRHICRTAARLNLPLEYNIGYEDYNDEHGITTIPHPAFWEIAAHEGCTAIIGVDAHNNQYLETPFYYD
RANETLQKLGMKVTDRIPFLNEK
>Mature_263_residues
MRTNYHTHTTRCLHATGSDEEFVLSAIKGGYQELGFSDHTPWEYHTDYVSDIRMTPEELPEYVESLRSLQKKYKDQISIK
IGLECEYFPEYIPWLKGVIKEYQLDYIIFGNHHFHTDEKFPYFGRNTHTVDMLELYEESAIEGMESGLFAYLAHPDLFMR
SYPEFDRHCKLVSRHICRTAARLNLPLEYNIGYEDYNDEHGITTIPHPAFWEIAAHEGCTAIIGVDAHNNQYLETPFYYD
RANETLQKLGMKVTDRIPFLNEK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30925; Mature: 30925

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNYHTHTTRCLHATGSDEEFVLSAIKGGYQELGFSDHTPWEYHTDYVSDIRMTPEELP
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHCCCCHHHHH
EYVESLRSLQKKYKDQISIKIGLECEYFPEYIPWLKGVIKEYQLDYIIFGNHHFHTDEKF
HHHHHHHHHHHHHHHCEEEEEECEEHHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCC
PYFGRNTHTVDMLELYEESAIEGMESGLFAYLAHPDLFMRSYPEFDRHCKLVSRHICRTA
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHH
ARLNLPLEYNIGYEDYNDEHGITTIPHPAFWEIAAHEGCTAIIGVDAHNNQYLETPFYYD
HHHCCCEEEECCCCCCCCCCCCEECCCCCCEEEECCCCCEEEEEEECCCCCEECCCCCHH
RANETLQKLGMKVTDRIPFLNEK
HHHHHHHHCCCHHHHCCCCCCCC
>Mature Secondary Structure
MRTNYHTHTTRCLHATGSDEEFVLSAIKGGYQELGFSDHTPWEYHTDYVSDIRMTPEELP
CCCCCCCCCEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHCCCCHHHHH
EYVESLRSLQKKYKDQISIKIGLECEYFPEYIPWLKGVIKEYQLDYIIFGNHHFHTDEKF
HHHHHHHHHHHHHHHCEEEEEECEEHHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCC
PYFGRNTHTVDMLELYEESAIEGMESGLFAYLAHPDLFMRSYPEFDRHCKLVSRHICRTA
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHHHH
ARLNLPLEYNIGYEDYNDEHGITTIPHPAFWEIAAHEGCTAIIGVDAHNNQYLETPFYYD
HHHCCCEEEECCCCCCCCCCCCEECCCCCCEEEECCCCCEEEEEEECCCCCEECCCCCHH
RANETLQKLGMKVTDRIPFLNEK
HHHHHHHHCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]