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The map label for this gene is lpxA [H]

Identifier: 29349613

GI number: 29349613

Start: 5541476

End: 5542243

Strand: Reverse

Name: lpxA [H]

Synonym: BT_4205

Alternate gene names: 29349613

Gene position: 5542243-5541476 (Counterclockwise)

Preceding gene: 29349614

Following gene: 29349612

Centisome position: 88.53

GC content: 41.93

Gene sequence:

>768_bases
ATGGTAAGTCCTCTAGCGTATATTCATCCCGAAGCTAAAATCGGAGAAAATGTAGAAATTGCGCCTTTTGTATTTATTGA
TAAAAACGTAGTTATTGGCGATAACAACAAGATTATGGCTAATGTGAACATCCTGTATGGTTCACGCATTGGTAATGGAA
ATACGATCTTTCCGGGTGCTGTTATCGGAGCAGTTCCACAGGACCTCAAGTTTCGTGGAGAAGAATCAACTGCTGAGATC
GGAGACAATAATCTGATTCGTGAGAATGTTACAGTCAACCGTGGTACGGCAGCTAAAGGGCGTACCATTGTAGGAAGCAA
CAACTTATTAATGGAAGGGGTGCATGTAGCACACGATGCACTGATCGGTAACGGATGTATTATCGGCAACTCCACCAAGA
TGGCAGGTGAAATCGTTATTGACGACAATGCTATTATCAGTGCCAATGTATTAATGCATCAGTTCTGCCATGTAGGCAGC
CATGTAATGATTCAGGGCGGATGCCGCTTCAGTAAAGATATCCCTCCTTATATCATTGCAGGACGTGAGCCCATAGCTTT
CAGCGGTATCAACATTATCGGCCTTCGTCGCCGTGGTTTTGCCAATGAAGTAATCGAAAGTATTCATAACGCTTACCGTA
TCATTTACCAAAGCGGTCTGAATACAACAGATGCATTGAAGAAAATTGAAGATGAAGTTGAGAAGAGTCCGGAGATTGAC
TACATCATCAATTTCATCCGTAATTCAGAACGTGGTATTATTAAATAA

Upstream 100 bases:

>100_bases
GGCATCTCCACAATGAAAGGTTATGCATTCGTTGGCGAAAAAGTCGTTTGCGAAGCAGAATTCATGGCACAAATAGTAAA
AAATAAATAAAACCAAAAAC

Downstream 100 bases:

>100_bases
ACAGTTCAAAATAGTCATATTATGATATACAGATTTACTATCATATCTGATGAAGTTGACGATTTTGTCAGAGAAATACA
AATTGATCCGGAAGCTACAT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MVSPLAYIHPEAKIGENVEIAPFVFIDKNVVIGDNNKIMANVNILYGSRIGNGNTIFPGAVIGAVPQDLKFRGEESTAEI
GDNNLIRENVTVNRGTAAKGRTIVGSNNLLMEGVHVAHDALIGNGCIIGNSTKMAGEIVIDDNAIISANVLMHQFCHVGS
HVMIQGGCRFSKDIPPYIIAGREPIAFSGINIIGLRRRGFANEVIESIHNAYRIIYQSGLNTTDALKKIEDEVEKSPEID
YIINFIRNSERGIIK

Sequences:

>Translated_255_residues
MVSPLAYIHPEAKIGENVEIAPFVFIDKNVVIGDNNKIMANVNILYGSRIGNGNTIFPGAVIGAVPQDLKFRGEESTAEI
GDNNLIRENVTVNRGTAAKGRTIVGSNNLLMEGVHVAHDALIGNGCIIGNSTKMAGEIVIDDNAIISANVLMHQFCHVGS
HVMIQGGCRFSKDIPPYIIAGREPIAFSGINIIGLRRRGFANEVIESIHNAYRIIYQSGLNTTDALKKIEDEVEKSPEID
YIINFIRNSERGIIK
>Mature_255_residues
MVSPLAYIHPEAKIGENVEIAPFVFIDKNVVIGDNNKIMANVNILYGSRIGNGNTIFPGAVIGAVPQDLKFRGEESTAEI
GDNNLIRENVTVNRGTAAKGRTIVGSNNLLMEGVHVAHDALIGNGCIIGNSTKMAGEIVIDDNAIISANVLMHQFCHVGS
HVMIQGGCRFSKDIPPYIIAGREPIAFSGINIIGLRRRGFANEVIESIHNAYRIIYQSGLNTTDALKKIEDEVEKSPEID
YIINFIRNSERGIIK

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=262, Percent_Identity=41.9847328244275, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27721; Mature: 27721

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSPLAYIHPEAKIGENVEIAPFVFIDKNVVIGDNNKIMANVNILYGSRIGNGNTIFPGA
CCCCCEEECCCCCCCCCCEEEEEEEEECEEEECCCCEEEEEEEEEEECEECCCCEECCCH
VIGAVPQDLKFRGEESTAEIGDNNLIRENVTVNRGTAAKGRTIVGSNNLLMEGVHVAHDA
HHHCCCCCCEECCCCCCHHCCCCCEEECCEEEECCCCCCCCEEECCCCEEECCHHHHHHH
LIGNGCIIGNSTKMAGEIVIDDNAIISANVLMHQFCHVGSHVMIQGGCRFSKDIPPYIIA
EECCCEEECCCCCEEEEEEECCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEE
GREPIAFSGINIIGLRRRGFANEVIESIHNAYRIIYQSGLNTTDALKKIEDEVEKSPEID
CCCCEEECCEEEEEEECCCCHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCCHH
YIINFIRNSERGIIK
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MVSPLAYIHPEAKIGENVEIAPFVFIDKNVVIGDNNKIMANVNILYGSRIGNGNTIFPGA
CCCCCEEECCCCCCCCCCEEEEEEEEECEEEECCCCEEEEEEEEEEECEECCCCEECCCH
VIGAVPQDLKFRGEESTAEIGDNNLIRENVTVNRGTAAKGRTIVGSNNLLMEGVHVAHDA
HHHCCCCCCEECCCCCCHHCCCCCEEECCEEEECCCCCCCCEEECCCCEEECCHHHHHHH
LIGNGCIIGNSTKMAGEIVIDDNAIISANVLMHQFCHVGSHVMIQGGCRFSKDIPPYIIA
EECCCEEECCCCCEEEEEEECCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEE
GREPIAFSGINIIGLRRRGFANEVIESIHNAYRIIYQSGLNTTDALKKIEDEVEKSPEID
CCCCEEECCEEEEEEECCCCHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCCHH
YIINFIRNSERGIIK
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA