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The map label for this gene is nuoA

Identifier: 29349475

GI number: 29349475

Start: 5300876

End: 5301226

Strand: Reverse

Name: nuoA

Synonym: BT_4067

Alternate gene names: 29349475

Gene position: 5301226-5300876 (Counterclockwise)

Preceding gene: 29349476

Following gene: 29349474

Centisome position: 84.68

GC content: 42.45

Gene sequence:

>351_bases
ATGAATTTTACATTTTTAGTTGTTGTTTTACTGACAGCGCTCGCTTTTGTCGGTGTAGTAATAGCCCTTTCACGAGCTAT
TTCACCACGTTCGTACAATGTACAAAAGTTTGAAGCTTATGAATGTGGTATACCAACGCGTGGTAAATCATGGATGCAGT
TCCGTGTAGGTTACTACCTGTTTGCCATCCTGTTCCTGATGTTCGACGTGGAAACAGCTTTTCTGTTCCCTTGGGCAGTA
GTTATGCATGACATGGGACCTCAGGGGCTCGTTAGTATTCTCTTCTTCTTTATTATTTTGGTTCTGGGCCTTGCTTATGC
CTGGAGGAAAGGAGCTTTGGAATGGAAATAA

Upstream 100 bases:

>100_bases
TTATCTTATTCGTCAATTCATTACAGTTGGTTTCATCCGGGTGTGGAGAAACTAATTGTTTATTTCTATATAATATTCAA
TCTAAACAGCTATTGAAATT

Downstream 100 bases:

>100_bases
CCAAAAAACCGAAAATAAAATCAATTCCGTATGATGAGTTCATCGACAATGAATCATTGGAAAAGTTGGTCAAGGAACTT
AATACCGGAGGAGCGAACGT

Product: NADH dehydrogenase I subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIPTRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAV
VMHDMGPQGLVSILFFFIILVLGLAYAWRKGALEWK

Sequences:

>Translated_116_residues
MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIPTRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAV
VMHDMGPQGLVSILFFFIILVLGLAYAWRKGALEWK
>Mature_116_residues
MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIPTRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAV
VMHDMGPQGLVSILFFFIILVLGLAYAWRKGALEWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=112, Percent_Identity=36.6071428571429, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_BACTN (Q8A0F4)

Other databases:

- EMBL:   AE015928
- RefSeq:   NP_812978.1
- GeneID:   1073431
- GenomeReviews:   AE015928_GR
- KEGG:   bth:BT_4067
- NMPDR:   fig|226186.1.peg.4065
- HOGENOM:   HBG605540
- OMA:   GERELTY
- PhylomeDB:   Q8A0F4
- ProtClustDB:   CLSK823774
- BioCyc:   BTHE226186:BT_4067-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13286; Mature: 13286

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13a69428)-; HASH(0x1399832c)-; HASH(0x13eb730c)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIPTRGKSWMQFRVGYYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHH
FAILFLMFDVETAFLFPWAVVMHDMGPQGLVSILFFFIILVLGLAYAWRKGALEWK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIPTRGKSWMQFRVGYYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHH
FAILFLMFDVETAFLFPWAVVMHDMGPQGLVSILFFFIILVLGLAYAWRKGALEWK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12663928