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The map label for this gene is pepC [H]

Identifier: 29346571

GI number: 29346571

Start: 1447289

End: 1448689

Strand: Reverse

Name: pepC [H]

Synonym: BT_1161

Alternate gene names: 29346571

Gene position: 1448689-1447289 (Counterclockwise)

Preceding gene: 29346578

Following gene: 29346570

Centisome position: 23.14

GC content: 49.54

Gene sequence:

>1401_bases
ATGAATAAACGAATTTTATCAGTTTTTGTTTGCTGTGCCCTTTACTATTCTGCACAGGCACAGGACGCGAAAGGCGGCAT
CAGCACTGACATGATGCAGCAAATCAAACAGAGTTATCAGGGCACTTCTACCGACAAGGCTATCCGGAACGCCATCAGCA
ACAACGACATCCGTAAGCTTGCCCTGAACCAGGACAACATGAAGGGGATGGATACACATTTTTCTGTCAAAGTGAACTCC
AAGGGGATCACCGACCAGAAATCGTCCGGACGCTGCTGGCTCTTCACCGGCCTGAACGTAATGCGTGCCAAAGCCATCGA
TAAATACCATCTGGGTTCTTTCGAATTCTCGCAAACCTATCCTTTCTTTTTCGACCAACTGGAAAAGGCCAACCTTTTCC
TTCAAGGCGTCATCGACACCAGCGACAAGCCTATGAACGATAAAATGGTGGAATGGCTGTTCCGCAATCCGTTGAGCGAC
GGCGGTACATTCACCGGAGTAGCGGACATCGTAAGCAAATACGGCCTCGTCCCCAAAGACGTGATGCCCGAAACGAACAG
CAGCGAAAACACCGCCCGCATGGCGAATCTGATCGCTCTGAAACTTCGCGAACAGGGGTTACAACTCCGTGACATGGCTT
CGAAAAAAGCTAAACCTGCCGCTATAGAGAACGCTAAAGTGGAAATGTTGAGCACCATTTACCGTATGCTTGTCCTGAAC
TTGGGCGTACCTCCTACAGAATTTACCTGGACGCAATATAATGTCAAAGGCGAGCCTGTAGAAACCGCCACCTACACCCC
GCTTTCTTTTCTGAAGAAATACGGTGACGAAAAGCTGATTGACAACTACGTCATGCTCATGAACGACCCCAGTCGCGAAT
ACTACAAATGTTATGAAATAGACTACGACCGCCACCGCTACGACGGCAAGAACTGGACATACGTCAACCTCCCGATCGAG
GACATCAAGGAGATGGCCATCGCCTCTCTGAAAGACAGCACCATGATGTATTACTCCTGCGACGTCGGCAAGTTCCTGAA
CTCTGACCGTGGTCTGCTCGACGTCAAAAACTATGATTACGACTCATTGATGGGCACCACCTTCAGCATGGACAAGAAGC
AGCGTATCCAAAGCTTTGCCAGCAGCTCCAGTCACGCCATGACCCTCATGGCAGTCGATCTGGACAAAAACGGAAAACCG
ACCAAATGGATGGTTGAAAATAGTTGGGGTGCCGGAGCCGGTTATCAAGGTCACCTCATCATGACAGATGAATGGTTCAA
CGAATATACCTTCCGTCTCGTTGTGGAAACGAAATACGTGACCCCGAAAGCACTCGAAGTCTTGAAACAAAAACCGATCC
GCCTGCCGGCATGGGATCCAATGTTTGCCGGCGAAGAATAA

Upstream 100 bases:

>100_bases
AAAAAAGAATCGTATTTTTGCCAATTAATAATATGTAAAACGAAATTGCCAACGGATTACTATTAGCATACAGGCAAAGT
TAATTTATAAACGATCTATA

Downstream 100 bases:

>100_bases
CCAACCGACAAACACGCTGCATAGACTTGTACGCTGCAAGGTCTTCCGGCCTACTTTATTAAAGAACGTGTGCGAACACA
AAAGGAATTACGGATATTTT

Product: putative aminopeptidase C

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MNKRILSVFVCCALYYSAQAQDAKGGISTDMMQQIKQSYQGTSTDKAIRNAISNNDIRKLALNQDNMKGMDTHFSVKVNS
KGITDQKSSGRCWLFTGLNVMRAKAIDKYHLGSFEFSQTYPFFFDQLEKANLFLQGVIDTSDKPMNDKMVEWLFRNPLSD
GGTFTGVADIVSKYGLVPKDVMPETNSSENTARMANLIALKLREQGLQLRDMASKKAKPAAIENAKVEMLSTIYRMLVLN
LGVPPTEFTWTQYNVKGEPVETATYTPLSFLKKYGDEKLIDNYVMLMNDPSREYYKCYEIDYDRHRYDGKNWTYVNLPIE
DIKEMAIASLKDSTMMYYSCDVGKFLNSDRGLLDVKNYDYDSLMGTTFSMDKKQRIQSFASSSSHAMTLMAVDLDKNGKP
TKWMVENSWGAGAGYQGHLIMTDEWFNEYTFRLVVETKYVTPKALEVLKQKPIRLPAWDPMFAGEE

Sequences:

>Translated_466_residues
MNKRILSVFVCCALYYSAQAQDAKGGISTDMMQQIKQSYQGTSTDKAIRNAISNNDIRKLALNQDNMKGMDTHFSVKVNS
KGITDQKSSGRCWLFTGLNVMRAKAIDKYHLGSFEFSQTYPFFFDQLEKANLFLQGVIDTSDKPMNDKMVEWLFRNPLSD
GGTFTGVADIVSKYGLVPKDVMPETNSSENTARMANLIALKLREQGLQLRDMASKKAKPAAIENAKVEMLSTIYRMLVLN
LGVPPTEFTWTQYNVKGEPVETATYTPLSFLKKYGDEKLIDNYVMLMNDPSREYYKCYEIDYDRHRYDGKNWTYVNLPIE
DIKEMAIASLKDSTMMYYSCDVGKFLNSDRGLLDVKNYDYDSLMGTTFSMDKKQRIQSFASSSSHAMTLMAVDLDKNGKP
TKWMVENSWGAGAGYQGHLIMTDEWFNEYTFRLVVETKYVTPKALEVLKQKPIRLPAWDPMFAGEE
>Mature_466_residues
MNKRILSVFVCCALYYSAQAQDAKGGISTDMMQQIKQSYQGTSTDKAIRNAISNNDIRKLALNQDNMKGMDTHFSVKVNS
KGITDQKSSGRCWLFTGLNVMRAKAIDKYHLGSFEFSQTYPFFFDQLEKANLFLQGVIDTSDKPMNDKMVEWLFRNPLSD
GGTFTGVADIVSKYGLVPKDVMPETNSSENTARMANLIALKLREQGLQLRDMASKKAKPAAIENAKVEMLSTIYRMLVLN
LGVPPTEFTWTQYNVKGEPVETATYTPLSFLKKYGDEKLIDNYVMLMNDPSREYYKCYEIDYDRHRYDGKNWTYVNLPIE
DIKEMAIASLKDSTMMYYSCDVGKFLNSDRGLLDVKNYDYDSLMGTTFSMDKKQRIQSFASSSSHAMTLMAVDLDKNGKP
TKWMVENSWGAGAGYQGHLIMTDEWFNEYTFRLVVETKYVTPKALEVLKQKPIRLPAWDPMFAGEE

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=454, Percent_Identity=36.1233480176211, Blast_Score=309, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6324090, Length=442, Percent_Identity=32.3529411764706, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI161077632, Length=446, Percent_Identity=32.5112107623318, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24640588, Length=446, Percent_Identity=32.5112107623318, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI161077630, Length=362, Percent_Identity=33.9779005524862, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI20130175, Length=464, Percent_Identity=25.4310344827586, Blast_Score=148, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 53136; Mature: 53136

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRILSVFVCCALYYSAQAQDAKGGISTDMMQQIKQSYQGTSTDKAIRNAISNNDIRKL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEE
ALNQDNMKGMDTHFSVKVNSKGITDQKSSGRCWLFTGLNVMRAKAIDKYHLGSFEFSQTY
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHCCCEECCCEECCCCC
PFFFDQLEKANLFLQGVIDTSDKPMNDKMVEWLFRNPLSDGGTFTGVADIVSKYGLVPKD
CHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
VMPETNSSENTARMANLIALKLREQGLQLRDMASKKAKPAAIENAKVEMLSTIYRMLVLN
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHH
LGVPPTEFTWTQYNVKGEPVETATYTPLSFLKKYGDEKLIDNYVMLMNDPSREYYKCYEI
CCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCEEEEEECCCHHHEEEEEC
DYDRHRYDGKNWTYVNLPIEDIKEMAIASLKDSTMMYYSCDVGKFLNSDRGLLDVKNYDY
CCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCEEEECCCCH
DSLMGTTFSMDKKQRIQSFASSSSHAMTLMAVDLDKNGKPTKWMVENSWGAGAGYQGHLI
HHHCCCEECCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCEEE
MTDEWFNEYTFRLVVETKYVTPKALEVLKQKPIRLPAWDPMFAGEE
EECCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKRILSVFVCCALYYSAQAQDAKGGISTDMMQQIKQSYQGTSTDKAIRNAISNNDIRKL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEE
ALNQDNMKGMDTHFSVKVNSKGITDQKSSGRCWLFTGLNVMRAKAIDKYHLGSFEFSQTY
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHCCCEECCCEECCCCC
PFFFDQLEKANLFLQGVIDTSDKPMNDKMVEWLFRNPLSDGGTFTGVADIVSKYGLVPKD
CHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHH
VMPETNSSENTARMANLIALKLREQGLQLRDMASKKAKPAAIENAKVEMLSTIYRMLVLN
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHH
LGVPPTEFTWTQYNVKGEPVETATYTPLSFLKKYGDEKLIDNYVMLMNDPSREYYKCYEI
CCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHCCEEEEEECCCHHHEEEEEC
DYDRHRYDGKNWTYVNLPIEDIKEMAIASLKDSTMMYYSCDVGKFLNSDRGLLDVKNYDY
CCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCCCEEEECCCCH
DSLMGTTFSMDKKQRIQSFASSSSHAMTLMAVDLDKNGKPTKWMVENSWGAGAGYQGHLI
HHHCCCEECCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCCEEE
MTDEWFNEYTFRLVVETKYVTPKALEVLKQKPIRLPAWDPMFAGEE
EECCCCCCEEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7851736 [H]