Click here to switch to the map view.

The map label for this gene is trxA [H]

Identifier: 29346087

GI number: 29346087

Start: 838793

End: 839152

Strand: Reverse

Name: trxA [H]

Synonym: BT_0677

Alternate gene names: 29346087

Gene position: 839152-838793 (Counterclockwise)

Preceding gene: 29346091

Following gene: 29346083

Centisome position: 13.4

GC content: 36.39

Gene sequence:

>360_bases
ATGAAAATTATAGATTTAACCAAAGAAAGCTTTGTTGAGAAAGTTGCTGATTATCAATCTTATCCGGATAATTGGGAATA
TAAAGGGAATAAACCTTGTTTAGTCGATTTTCATGCTCCATGGTGTGGTTATTGCAAGGCATTATCACCCATATTGGACC
AATTAGCAGAAGAATATAAAGGGAGACTGGACATTTATAAAGTAGACGTCGATCAGGAAGAGGAACTGGAAAGTGCATTC
AAGATTCGGACAATTCCCAACCTTTTGCTTTGCCCGGTGAATGGCAAACCGATAATGAAACTCGGTACAATGAATAAGGT
TCAATTGAAAGAGTTTATAGAAACGACTCTATTTTCATGA

Upstream 100 bases:

>100_bases
AATTGTAAACACAACAGGAAGAATGGCTATCCCTCTTTCTCTACCATACCCCTATCTTTGCAAAGTAGAAATAAATAATG
AATCATTAAAAACAGGAAAT

Downstream 100 bases:

>100_bases
TAAAATAGAATATAGAGTACTCACATTACTACTTTTCTTACTGAAAAAGTCCGAATCCCAATTGCTTTTTGCAATTTAAA
GGTTCGGACTTTCTATTTTC

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKIIDLTKESFVEKVADYQSYPDNWEYKGNKPCLVDFHAPWCGYCKALSPILDQLAEEYKGRLDIYKVDVDQEEELESAF
KIRTIPNLLLCPVNGKPIMKLGTMNKVQLKEFIETTLFS

Sequences:

>Translated_119_residues
MKIIDLTKESFVEKVADYQSYPDNWEYKGNKPCLVDFHAPWCGYCKALSPILDQLAEEYKGRLDIYKVDVDQEEELESAF
KIRTIPNLLLCPVNGKPIMKLGTMNKVQLKEFIETTLFS
>Mature_119_residues
MKIIDLTKESFVEKVADYQSYPDNWEYKGNKPCLVDFHAPWCGYCKALSPILDQLAEEYKGRLDIYKVDVDQEEELESAF
KIRTIPNLLLCPVNGKPIMKLGTMNKVQLKEFIETTLFS

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=116, Percent_Identity=40.5172413793103, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1788936, Length=91, Percent_Identity=35.1648351648352, Blast_Score=66, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=84, Percent_Identity=35.7142857142857, Blast_Score=61, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24664269, Length=101, Percent_Identity=33.6633663366337, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28573567, Length=73, Percent_Identity=36.986301369863, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 13783; Mature: 13783

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDLTKESFVEKVADYQSYPDNWEYKGNKPCLVDFHAPWCGYCKALSPILDQLAEEYK
CCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
GRLDIYKVDVDQEEELESAFKIRTIPNLLLCPVNGKPIMKLGTMNKVQLKEFIETTLFS
CCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIDLTKESFVEKVADYQSYPDNWEYKGNKPCLVDFHAPWCGYCKALSPILDQLAEEYK
CCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
GRLDIYKVDVDQEEELESAFKIRTIPNLLLCPVNGKPIMKLGTMNKVQLKEFIETTLFS
CCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]