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The map label for this gene is mrr [H]

Identifier: 29144811

GI number: 29144811

Start: 4731759

End: 4732673

Strand: Direct

Name: mrr [H]

Synonym: t4577

Alternate gene names: 29144811

Gene position: 4731759-4732673 (Clockwise)

Preceding gene: 29144805

Following gene: 29144812

Centisome position: 98.74

GC content: 52.79

Gene sequence:

>915_bases
ATGGCTGTTCCAACATATGACAAATTTATTGAACCAGTGTTGCGTTTTCTGGCCACTCGACCCGAGGGCGCTTTGGTCAG
AGAAGTGCGTGAAGCTGCAGCCGAAATGCTTGGGTTAAATGAGCAGCAGCGTGCAGAGGTGATTACCAGTGGACAACTGA
CGTACCAGAACCGCACCGGTTGGGCGCACGATCGTCTCAAACGCGCCGGGTTATCGCAGAGCCTATCCCGGGGAAAATGG
TGTTTAACACCAGCGGGAATGAGCTGGGTTGCCTCGCATCCGCAGCCGATGACCGAGCAGGAAGTGAGTCATTTTGCTTG
TGATTTTAACGGCGTAAAGCTCAGTAAGCCGGCAGATGCGGTGGCGTTAGATCCACAGCCAGAATCGATTGAGGATGATG
AGCTTGCCAGAAGCAGCCCGGACGATCGCCTGGAGCAAGCGCTCAATGAGATTCGTGAATCTGTTGCCGAAGAATTGCTG
GAGAACCTGCTTCAGGTTTCGCCGGCGCGTTTTGAAGTGATTGTGTTAGATGTGTTGCACCGCCTGGGATATGGCGGTCA
TCGCGGTGATTTGCAGCGCGTCGGGGGAACCGGCGATGGCGGCATTGACGGTATTATCTCTCTCGATAAGCTCGGGCTGG
AAAAAGTCTACGTTCAGGCCAAACGCTGGAAAGGCACCGTCGGGAGCGCTGAAGTCAGGGGCTTTTATGGTGCATTGCCT
GAGCAAAAAGTGAAACGTGGCGTCTTTATTACCACCTCAGGCTTTACGGCGCATGCCAGAGACTATGCTAACAAAGTTGA
AGGTCTGGTGCTGGTGGATGGCGACAGGCTGGTGCATCTGATGATTGATAATGATATTGGCGTATCCTCACGTTTACTCA
AGTTGCCAAAGCTCGATATGGATTACTTTGAGTAG

Upstream 100 bases:

>100_bases
ACGAACAATCAGAGAGTAACTGCTTCTTTCCTAATGTTTTCCTGAAGAGTATCGTTCTCCGGCGGGGTATCTAATCTATA
TCAATAGCAGGGATGGATTT

Downstream 100 bases:

>100_bases
TGGTAACGCTGGAACCTGATTACGGGTAATTGAGATGGACCACGTTGTGGGCACCTGTGTTTCCTCTCGCCCAGAAATCA
CGTGACTTTCTATGGCTGCG

Product: mrr restriction system protein

Products: NA

Alternate protein names: EcoKMrr [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQRAEVITSGQLTYQNRTGWAHDRLKRAGLSQSLSRGKW
CLTPAGMSWVASHPQPMTEQEVSHFACDFNGVKLSKPADAVALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELL
ENLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAKRWKGTVGSAEVRGFYGALP
EQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLMIDNDIGVSSRLLKLPKLDMDYFE

Sequences:

>Translated_304_residues
MAVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQRAEVITSGQLTYQNRTGWAHDRLKRAGLSQSLSRGKW
CLTPAGMSWVASHPQPMTEQEVSHFACDFNGVKLSKPADAVALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELL
ENLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAKRWKGTVGSAEVRGFYGALP
EQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLMIDNDIGVSSRLLKLPKLDMDYFE
>Mature_303_residues
AVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQRAEVITSGQLTYQNRTGWAHDRLKRAGLSQSLSRGKWC
LTPAGMSWVASHPQPMTEQEVSHFACDFNGVKLSKPADAVALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELLE
NLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAKRWKGTVGSAEVRGFYGALPE
QKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLMIDNDIGVSSRLLKLPKLDMDYFE

Specific function: Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA [H]

COG id: COG1715

COG function: function code V; Restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790811, Length=304, Percent_Identity=77.3026315789474, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011856
- InterPro:   IPR011335
- InterPro:   IPR007560 [H]

Pfam domain/function: PF04471 Mrr_cat [H]

EC number: NA

Molecular weight: Translated: 33595; Mature: 33463

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQRAEVITSGQLTYQNRTG
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCC
WAHDRLKRAGLSQSLSRGKWCLTPAGMSWVASHPQPMTEQEVSHFACDFNGVKLSKPADA
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEECCCCCC
VALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELLENLLQVSPARFEVIVLDVLH
EEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAKRWKGTVGSAEVRGFYGALP
HHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
EQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLMIDNDIGVSSRLLKLPKLDM
HHHHHCCEEEEECCCCHHHHHHHHHHCEEEEECCCEEEEEEEECCCCHHHHHHHCCCCCC
DYFE
CCCC
>Mature Secondary Structure 
AVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQRAEVITSGQLTYQNRTG
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCC
WAHDRLKRAGLSQSLSRGKWCLTPAGMSWVASHPQPMTEQEVSHFACDFNGVKLSKPADA
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCHHHHHHHHCCCCCEEECCCCCC
VALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELLENLLQVSPARFEVIVLDVLH
EEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYVQAKRWKGTVGSAEVRGFYGALP
HHCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCC
EQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDRLVHLMIDNDIGVSSRLLKLPKLDM
HHHHHCCEEEEECCCCHHHHHHHHHHCEEEEECCCEEEEEEEECCCCHHHHHHHCCCCCC
DYFE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650347; 7610040; 9278503 [H]