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The map label for this gene is ytfL [H]

Identifier: 29144706

GI number: 29144706

Start: 4605664

End: 4607007

Strand: Reverse

Name: ytfL [H]

Synonym: t4461

Alternate gene names: 29144706

Gene position: 4607007-4605664 (Counterclockwise)

Preceding gene: 29144707

Following gene: 29144705

Centisome position: 96.14

GC content: 50.07

Gene sequence:

>1344_bases
ATGTTAAACAGTATATTCATTATATTCTGCCTGATCGCTGTAAGTGCGTTCTTCTCCATCTCCGAGATCTCGCTTGCCGC
ATCACGTAAGATTAAACTTAAGTTATTAGCTGATGAAGGCAGTATCAACGCACAACGCGTATTGAAAATGCAGGAAAATC
CCGGCATGTTTTTCACCGTTGTGCAAATTGGCCTGAACGCCGTCGCTATTCTTGGCGGTATCGTCGGCGATGCGGCATTT
TCGCCCGCCTTTTCCGCCCTTTTCTCGCACTATATGTCGCCAGAACTCTCCGAGCAGTTGAGCTTTATTCTCTCTTTCTC
GCTGGTGACGGGGCTGTTTATCCTGTTCGCGGATTTAACCCCGAAACGCATCGGTATGATTGCGCCAGAAGCTGTGGCTT
TGCGTATCATCAACCCGATGCGCTTCTGCCTGTTCGTTTTTCGCCCGCTGGTGTGGCTGTTTAACGGCATGGCAAACAAC
ATCTTCCGCCTGTTCAAAATTCCAATGGTGCGGAAAGACGACATTACTTCTGATGATATTTACGCGGTGGTGGAAGCCGG
CGCGCTGGCGGGCGTCTTGCGCAAGCAAGAGCACGAACTGATTGAAAATGTGTTTGAACTTGAATCCCGCACCGTACCGT
CTTCTATGACGTCGCGCGAAAGTATCATCTGGTTTGATCTACACGAAGACGAACAAAGCCTGAAGAAAAAGGTAGCCGAA
CATCCGCACTCAAAATTTTTGGTGTGTAATGAAGATATCGACCACATCATCGGCTATGTAGATTCCAAAGATCTGCTGAA
CCGCGTGCTGGCGAACCAAAGTATGGCGCTGAATAGCGGCGTGCAAATTCGCAATACCTTGATTGTGCCGGATACGCTGA
CCCTTTCTGAGGCGCTGGAAAGTTTCAAAACGGCGGGCGAAGATTTCGCGGTCATTATGAATGAATACGCGCTGGTCGTC
GGTATCATTACGCTGAACGATGTGATGACCACGCTAATGGGTGACCTGGTCGGCCAGGGACTGGAAGAGCAAATTGTGGC
GCGCGATGAAAATTCCTGGCTGGTTGACGGCGGCACGCCGATTGACGACGTCATGCGCGTGCTGGATATCGATGAGTTTC
CGCAATCCGGCAACTATGAAACCATTGGCGGCTTTATGATGTTTATGCTGCGCAAGATCCCAAAACGTACTGATTCGGTG
AAGTTTTCCGGCTACAAATTTGAAGTGGTGGATATCGACAACTACCGTATCGATCAGTTGCTGGTGACGCGTCTCGACAA
TAAAAGCAACGTACCGGCGCCGAAACTGCCCGATGCGCAAGGTAAAGAAGACAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GAACTTATCGGCTCACTGCTACGAGCCGGTTTTCATTAAACGTTACCACACGGATTTATAAACTTCCCTTCCGAGGATCT
GGCGTTTCGCCGGATAAGAT

Downstream 100 bases:

>100_bases
AATCCGTTTGCCAGAAACATCAACGGCTCCTGATTCAGGAGCCGTTTTTTTGTTGTCTATGGAAAACCCCCAGCTAGGCT
GGGGGTTCCGGAAAGCTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA

Sequences:

>Translated_447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA
>Mature_447_residues
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESIIWFDLHEDEQSLKKKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=25, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI1790664, Length=447, Percent_Identity=91.7225950782998, Blast_Score=845, Evalue=0.0,
Organism=Escherichia coli, GI145693175, Length=421, Percent_Identity=22.8028503562945, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=32.9218106995885, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=27.0833333333333, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786879, Length=262, Percent_Identity=24.4274809160305, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49768; Mature: 49768

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHEECCCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANNIFRLFKIPMVRKDDITSDDI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESIIWFDLHEDEQSLKKKVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNSGVQIRNTLIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHHCCCHHHCCCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCCCC
IDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFSGYKFEVVDIDNYRIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHH
LVTRLDNKSNVPAPKLPDAQGKEDSAA
HHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINAQRVLKMQENPGMFFTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHEECCCCCEEEEH
VQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSFILSFSLVTGLFILFADLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANNIFRLFKIPMVRKDDITSDDI
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
YAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTSRESIIWFDLHEDEQSLKKKVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMALNSGVQIRNTLIVPDTLTLSEALE
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHHCCCHHHCCCCEEEEEEECCCCHHHHHHHH
SFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLVDGGTP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEECCCCC
IDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFSGYKFEVVDIDNYRIDQL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCHHHHH
LVTRLDNKSNVPAPKLPDAQGKEDSAA
HHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]