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The map label for this gene is dipZ [H]

Identifier: 29144623

GI number: 29144623

Start: 4526778

End: 4528481

Strand: Reverse

Name: dipZ [H]

Synonym: t4374

Alternate gene names: 29144623

Gene position: 4528481-4526778 (Counterclockwise)

Preceding gene: 29144624

Following gene: 29144622

Centisome position: 94.5

GC content: 56.28

Gene sequence:

>1704_bases
ATGGCTCAACGCATCTTTACGCTGATCCTGCTGCTGTGCAGCACATCCGCCTTCGCCGGATTATTCGACGCGCCGGGTCG
CTCGCAGTTCGTCCCTGCCGACCGGGCGTTTGTTTTTGATTTTCAGCAAAATCAACACGATCTTACCCTCTCCTGGCAGG
TAAAAGAGGGTTACTACCTTTACCGTAAACAAATCAGTATCACGCCGACGAAAGCGGATATCGCCGCAGTCCAACTCCCG
GCAGGCGTCTGGCATGAAGATGAATTCTACGGAAAAAGCGAAATCTACCGTAAGCGGCTAAACGTTCCGGTAACGGTTAA
CCAGGCGGCGGCTGGCGCGACATTAACGATAACGTACCAGGGGTGCGCCGATGCGGGATTCTGTTATCCGCCGGAAACGA
AAACGGTGCCGCTAAGTGAAGTCGCCGCGGCAATAGACGCCACGCCGACGCCTGCTGTCACCCAGACGGGTGAGACGTCA
AAACCCGCCGCCCAGCTACCTTTTTCTGCGCTCTGGGCGCTACTGATCGGCATAGGCATCGCCTTTACGCCCTGCGTTTT
ACCTATGTATCCGCTGATTTCCGGTATTGTCCTGGGGGGAAGGCAACGTTTGTCGACGGGGCGCGCACTGCTGCTGGCCT
TTATCTATGTACAAGGGATGGCGCTGACCTATACCGCACTGGGTCTGGTCGTCGCCGCGGCGGGATTACAGTTTCAGGCG
GCGCTGCAGCACCCTTATGTGTTAATCGGCCTTGCCATCGTGTTCACCCTGCTTGCGTTGTCGATGTTTGGCCTGTTCAC
ACTACAGCTCCCCTCCTCACTGCAAACCCGGCTGACATTAATGAGTAATCGTCAGCAAGGCGGCTCGCCCGGCGGTGTTT
TTGTTATGGGGGCGATTGCAGGATTAATTTGCTCGCCCTGTACCACAGCGCCATTAAGCGCGATCCTGCTTTATATCGCT
CAGAGCGGCAACATGTGGCTGGGCGGCGGTACGCTGTATTTGTATGCATTAGGTATGGGTCTGCCGCTAATGCTGGTCAC
CGTGTTTGGCAACCGTCTGCTACCGAAAAGCGGCCCGTGGATGGCGCATGTTAAAACCGCTTTTGGTTTCGTGATCCTCG
CGTTACCGGTCTTTTTACTGGAGCGGATTATTGGCGAGGCTTGGGGTTTACGTCTGTGGTCGCTGCTGGGCGTCGCTTTC
TTTGGTTGGGCCTTTATCACCAGCCTTCAGGCCAGACGAGCGTGGATGCGTATCGTACAGATTATCCTGCTGGCGGCAGC
GCTCATTAGCGTGCGGCCTCTACAAGATTGGGCATTCGGATCGCCATCCGCGCAAGCTCCAGCGCACCTCAATTTCACGG
CTATTTCTACCGTGGATGAACTCAATCAGGCGCTGGCGCAGGCCAAAGGCAAACCCGTTATGCTGGATTTCTACGCCGAC
TGGTGCGTGGCCTGTAAAGAGTTTGAAAAGTATACCTTCAGCGATCCGAGGGTCCAGCAGGTGCTCGGCGACACGGTGCT
CTTGCAGGCTAACGTCACCGCTAACAATGCGCAGGACGTCGCGCTGTTAAAGCATCTGCAAGTTCTCGGGCTGCCCACCA
TTCTGTTCTTTGATGCCCAAGGCCAGGAACAGCCGCAAGCGCGAGTCACCGGCTTTATGGACGCCGCCACCTTTAGCGCG
CATTTGCACGATCGCCAACCATGA

Upstream 100 bases:

>100_bases
ATCAGCAAGCGCTTATCGACTGCCTGAAGTCTCATCACCCGTATCAAACGCCTGAACTTCTGGTTTTACCTGTTACTCAC
GGAGATACTGATTACCTCTC

Downstream 100 bases:

>100_bases
GCGACACTTGCAAAAGCAAAGACGGAGGAGAATACCGTGCAACGTGAAGATATTCTGGGAGAAGCCCTGAAATTACTGGA
GACGCAAGGGATAGCCGATA

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLP
AGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTITYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETS
KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIA
QSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAF
FGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
WCVACKEFEKYTFSDPRVQQVLGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFDAQGQEQPQARVTGFMDAATFSA
HLHDRQP

Sequences:

>Translated_567_residues
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLP
AGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTITYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETS
KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIA
QSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAF
FGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
WCVACKEFEKYTFSDPRVQQVLGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFDAQGQEQPQARVTGFMDAATFSA
HLHDRQP
>Mature_566_residues
AQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLPA
GVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTITYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETSK
PAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQAA
LQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQ
SGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFF
GWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYADW
CVACKEFEKYTFSDPRVQQVLGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFDAQGQEQPQARVTGFMDAATFSAH
LHDRQP

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=568, Percent_Identity=87.5, Blast_Score=1009, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 61356; Mature: 61225

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYL
CHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEE
YRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTITYQ
EEEEEEECCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHCCCCEEECCCCCCEEEEEEEC
GCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETSKPAAQLPFSALWALLIGIGI
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
AFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPW
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEHHHHCCHHHHHHHHHCCCCCCCCCCC
MAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFFGWAFITSLQARRAWMRIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
HHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEHHH
WCVACKEFEKYTFSDPRVQQVLGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFDAQ
HHHHHHHHHHCCCCCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECC
GQEQPQARVTGFMDAATFSAHLHDRQP
CCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQNQHDLTLSWQVKEGYYL
HHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEE
YRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNVPVTVNQAAAGATLTITYQ
EEEEEEECCCCCCCEEEEECCCCCCCHHHCCHHHHHHHHCCCCEEECCCCCCEEEEEEEC
GCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETSKPAAQLPFSALWALLIGIGI
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHH
AFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQGMALTYTALGLVVAAAGLQFQA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIA
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
GLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLVTVFGNRLLPKSGPW
HHHCCCCCCHHHHHHHHHHHCCCCEEECCCHHEEHHHHCCHHHHHHHHHCCCCCCCCCCC
MAHVKTAFGFVILALPVFLLERIIGEAWGLRLWSLLGVAFFGWAFITSLQARRAWMRIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILLAAALISVRPLQDWAFGSPSAQAPAHLNFTAISTVDELNQALAQAKGKPVMLDFYAD
HHHHHHHHHHCCCCHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEEEHHH
WCVACKEFEKYTFSDPRVQQVLGDTVLLQANVTANNAQDVALLKHLQVLGLPTILFFDAQ
HHHHHHHHHHCCCCCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECC
GQEQPQARVTGFMDAATFSAHLHDRQP
CCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA